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1.发明授权公开(公告)号：US06804552B2
公开(公告)日：2004-10-12
申请号：US10004025
申请日：2001-10-31
IPC分类号： A61N100
CPC分类号： A61N1/37 , A61N1/368 , A61N1/3718 , A61N1/3912 , A61N1/3956
摘要： An improved switching system for use with an implantable medical device (IMD) is described. The system utilizes Micro-Electrical-Mechanical system (MEMs) switches in place of one or more switches formerly implemented using transistor networks. Any type of switching circuit used within an IMD may be implemented using this technology. For example, MEMs switches may be utilized in a circuit for selectably delivering electrical stimulation to a patient, and/or in a circuit for providing surge protection. The fabrication of the MEMs switches may be performed using one or more separate tubs or wells on a silicon substrate to isolate switching circuitry from other IMD circuitry.
摘要翻译： 描述了一种用于可植入医疗装置（IMD）的改进的切换系统。 该系统采用微机电系统（MEM）开关代替先前使用晶体管网络实现的一个或多个开关。 可以使用该技术来实现在IMD内使用的任何类型的开关电路。 例如，可以在电路中使用MEM开关，以可选择地向患者输送电刺激，和/或在用于提供浪涌保护的电路中。 可以使用硅衬底上的一个或多个单独的桶或阱来执行MEM开关的制造，以将开关电路与其他IMD电路隔离开来。
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公开(公告)号：US06438422B1
公开(公告)日：2002-08-20
申请号：US09467288
申请日：1999-12-20
IPC分类号： A61N1362
CPC分类号： G06F1/324 , A61N1/025 , A61N1/3605 , A61N1/362 , A61N1/378 , G06F1/3203 , G06F1/3296 , H03K19/0019 , Y02D10/126 , Y02D10/172
摘要： A system for minimizing power dissipation within an implantable medical device through use of adiabatic logic is disclosed. The system includes a first and a second sub-circuit of the implantable medical device. An electrical connection interconnects the first and the second sub-circuits, the electrical connection including a capacitive element. Circuitry, which charges the capacitive element of the electrical connection to generate a ramp logic signal, is connected to the capacitive element. The ramp logic signal includes a frequency of less than 500 kilohertz, thereby creating a low frequency, low power system which reduces energy dissipation to the surrounding environment.
摘要翻译： 公开了一种通过使用绝热逻辑来最小化可植入医疗装置内的功率耗散的系统。 该系统包括可植入医疗装置的第一和第二子电路。 电连接将第一和第二子电路互连，电连接包括电容元件。 将电连接的电容元件充电以产生斜坡逻辑信号的电路连接到电容元件。 斜坡逻辑信号包括小于500千赫的频率，从而产生低频，低功率系统，从而减少对周围环境的能量耗散。
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3.发明授权Interrogation of an implantable medical device using broadcast audible sound communication 失效使用广播声音通信的可植入医疗设备的询问公开(公告)号：US06370433B1
公开(公告)日：2002-04-09
申请号：US09491205
申请日：2000-01-25
IPC分类号： A61N136
CPC分类号： A61N1/3727 , A61N1/37217 , A61N1/37223
摘要： Methods and apparatus for communication of implantable medical device (IMD) information, including interrogation of programmed parameter values, operating modes and conditions of operation, confirmation of programmed changes thereof, interrogation of data stored in the IMD, and patient warnings or other messages by RF transmission of audible sounds generated by the IMD are disclosed. The IMD includes an RF transmitter that broadcasts or transmits audible sounds including voiced statements or musical tones stored in analog memory correlated to a programming or interrogation operating algorithm or to a warning trigger event. The broadcast radio signal is received, and the audible sounds are demodulated and reproduced by a radio receiver as voiced statements or musical is tones that convey human understandable messages comprising IMD information generated during programming and interrogation sessions and warnings or status messages to the patient at other times.
摘要翻译： 用于通信植入式医疗装置（IMD）信息的方法和装置，包括询问编程的参数值，操作模式和操作条件，确定其编程的变化，询问存储在IMD中的数据，以及通过RF的患者警告或其他消息 公开了由IMD产生的可听见的声音的传输。 IMD包括RF发射器，其广播或发送与编程或询问操作算法相关的模拟存储器中存储的有声语音或音调的声音或发音，或警告触发事件。 广播无线电信号被接收，并且可听见的声音被无线电接收机解调和再现，因为语音或音乐是将编程和询问会话期间生成的包含IMD信息的人可理解的消息和警告或状态消息传递给患者的音调 次
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4.发明授权Broadcast audible sound communication of programming change in an implantable medical device 失效广播可植入式医疗设备中的编程改变的声音通信公开(公告)号：US06216038B1
公开(公告)日：2001-04-10
申请号：US09491395
申请日：2000-01-25
IPC分类号： A61N136
CPC分类号： A61N1/3727 , A61N1/37217 , A61N1/37223 , A61N1/37258 , Y10S128/903
摘要： Methods and apparatus for communication of implantable medical device (IMD) information, including interrogation of programmed parameter values, operating modes and conditions of operation, confirmation of programmed changes thereof, interrogation of data stored in the IMD, and patient warnings or other messages by RF transmission of audible sounds generated by the IMD are disclosed. The IMD includes an RF transmitter that broadcasts or transmits audible sounds including voiced statements or musical tones stored in analog memory correlated to a programming or interrogation operating algorithm or to a warning trigger event. The broadcast radio signal is received, and the audible sounds are demodulated and reproduced by a radio receiver as voiced statements or musical tones that convey human understandable messages comprising IMD information generated during programming and interrogation sessions and warnings or status messages to the patient at other.
摘要翻译： 用于通信植入式医疗装置（IMD）信息的方法和装置，包括询问编程的参数值，操作模式和操作条件，确定其编程的变化，询问存储在IMD中的数据，以及通过RF的患者警告或其他消息 公开了由IMD产生的可听见的声音的传输。 IMD包括RF发射器，其广播或发送与编程或询问操作算法相关的模拟存储器中存储的有声语音或音调的声音或发音，或警告触发事件。 广播无线电信号被接收，并且声音由无线电接收机解调和再现，作为语音或乐音，其将可编程和询问会话期间生成的包含IMD信息的人可理解的消息和警告或状态消息传达给患者。
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公开(公告)号：US6082367A
公开(公告)日：2000-07-04
申请号：US69559
申请日：1998-04-29
CPC分类号： A61N1/37258
摘要： Methods and apparatus for communication of implantable medical device (IMD) information, including confirmation of programming and programmed parameter values, operating modes and programmed changes thereof and data stored in the IMD, by emission of audible sounds by the IMD are disclosed. The IMD includes an audio transducer that emits audible sounds including voiced statements or musical tones stored in analog memory correlated to a programming or interrogation operating algorithm or to a warning trigger event. The audible sounds can comprise the sole uplink transmission or may augment the contemporaneous uplink RF transmission of stored data, and/or programmed operating modes and parameters and/or device operations and states in an interrogation or during programming. To conserve energy, the audible sounds accompanying interrogation and programming of the IMD are at a low volume that preferably cannot be heard without use of an external audio amplifier or stethoscope. Voiced statements warning of battery energy depletion or imminent delivery of a therapy are emitted at a higher volume that is sufficient to be heard by the patient, so that the patient can take appropriate action. The volume of audible sounds confirming programmed changes made by a patient using a limited function programmer or magnet is also increased so that the patient can hear them.
摘要翻译： 公开了通过IMD发出可听见的声音来传送植入式医疗装置（IMD）信息的方法和装置，包括编程和编程参数值的确认，操作模式及编程改变以及存储在IMD中的数据。 IMD包括音频换能器，其发射可听声音，包括存储在与编程或询问操作算法相关的模拟存储器中的语音或音调，或者到警告触发事件。 可听见的声音可以包括唯一的上行链路传输，或者可以在询问中或在编程期间增加存储数据的同时期上行链路RF传输和/或编程的操作模式和参数和/或设备操作和状态。 为了节省能量，伴随着IMD的询问和编程的可听见的声音处于较低的音量，最好在不使用外部音频放大器或听诊器的情况下听不到声音。 电池能量消耗或治疗即将发送的声明声明以足以由患者听到的较高音量发出，以便患者能够采取适当的动作。 使用有限功能的编程器或磁铁确认病人进行的编程改变的可听见声音的音量也增加，以便患者可以听到它们的声音。
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6.发明授权Feedthrough assembly for implantable medical devices and methods for providing same 有权用于可植入医疗器械的馈通组件及其提供方法
公开(公告)号：US6052623A
公开(公告)日：2000-04-18
申请号：US201059
申请日：1998-11-30
IPC分类号： A61N1/375
CPC分类号： A61N1/3754
摘要： A feedthrough assembly for an implantable medical device includes one or more electrically conductive pins extending through apertures in a case of the medical device with the electrically conductive pins being insulated from the case. The feedthrough assembly further includes a printed circuit board having a diode protection circuit mounted thereon. The printed circuit board forms at least a part of electrically conductive paths for connection of the electrically conductive pins to a medical device circuit assembly mounted within the case. The printed circuit board further provides for electrical connection of the diode protection circuit mounted thereon between the electrically conductive pins and the case.
摘要翻译： 用于可植入医疗装置的馈通组件包括在医疗装置的壳体中延伸穿过孔的一个或多个导电销，其中导电销与壳体绝缘。 馈通组件还包括其上安装有二极管保护电路的印刷电路板。 印刷电路板形成用于将导电针连接到安装在壳体内的医疗装置电路组件的导电路径的至少一部分。 印刷电路板还提供安装在其上的二极管保护电路在导电引脚和外壳之间的电连接。
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7.发明授权Audible sound confirmation of programming change in an implantable medical device 有权植入式医疗设备中编程改变的声音确认
公开(公告)号：US6044301A
公开(公告)日：2000-03-28
申请号：US282593
申请日：1999-03-31
CPC分类号： A61N1/37258
摘要： Methods and apparatus for confirming programming of implantable medical device (IMD) operating parameter values and operating modes by emission of audible sounds by the IMD are disclosed. The IMD includes an audio transducer that emits audible sounds including voiced statements or musical tones stored in analog memory correlated to a programming or interrogation operating algorithm or to a warning trigger event. The audible sounds can comprise the sole uplink transmission or may augment the contemporaneous uplink RF transmission of stored data, and/or programmed operating modes and parameters and/or device operations and states in an interrogation or during programming. To conserve energy, the audible sounds accompanying interrogation and programming of the IMD are at a low volume that preferably cannot be heard without use of an external audio amplifier or stethoscope. Voiced statements warning of battery energy depletion or imminent delivery of a therapy are emitted at a higher volume that is sufficient to be heard by the patient, so that the patient can take appropriate action. The volume of audible sounds confirming programmed changes made by a patient using a limited function programmer or magnet is also increased so that the patient can hear them.
摘要翻译： 公开了通过IMD发出可听见的声音来确认可植入医疗装置（IMD）操作参数值和操作模式的编程的方法和装置。 IMD包括音频换能器，其发射可听声音，包括存储在与编程或询问操作算法相关的模拟存储器中的语音或音调，或者到警告触发事件。 可听见的声音可以包括唯一的上行链路传输，或者可以在询问中或在编程期间增加存储数据的同时期上行链路RF传输和/或编程的操作模式和参数和/或设备操作和状态。 为了节省能量，伴随着IMD的询问和编程的可听见的声音处于较低的音量，最好在不使用外部音频放大器或听诊器的情况下听不到声音。 电池能量消耗或治疗即将发送的声明声明以足以由患者听到的较高音量发出，以便患者能够采取适当的动作。 使用有限功能的编程器或磁铁确认病人进行的编程改变的可听见声音的音量也增加，以便患者可以听到它们的声音。
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公开(公告)号：US5324310A
公开(公告)日：1994-06-28
申请号：US907369
申请日：1992-07-01
CPC分类号： A61N1/3706 , A61N1/365 , A61N1/3716
摘要： A pacemaker having two bipolar leads, one atrial, one ventricular, each with TIP and RING electrodes, configured as for conventional bipolar pacing/sensing in both chambers. Switching circuitry in the pacemaker is operable to select from among various possible sensing configurations, including one configuration in which sensing is performed between the ring electrodes of the respective pacing/sensing leads. Pacing is preferably performed in a conventional unipolar configuration in each chamber, from the respective tip electrodes. The "ring-to-ring" EGM signal is applied to filtering and EGM amplifier circuitry, and then provided to a telemetry system for transmission to an external receiver. The ring-to-ring EGM signal possesses the high resolution properties of conventional intracardiac signals, and is relatively unaffected by the after-potentials and tissue polarization effects that arise when the same lead is used for pacing and sensing. Additionally, the ring-to-ring EGM signal is a composite of atrial and ventricular electrical signals, and thus has an appearance similar to that of surface ECGS. In the disclosed embodiment, separate atrial and ventricular EGM amplifiers are provided, with the atrial EGM amplifier receiving a conventional atrial unipolar sensing signal and the ventricular EGM amplifier receiving a conventional ventricular unipolar sensing signal. The outputs from the respective atrial and ventricular EGM amplifiers are algebraically multiplied, and the multiplied signal is applied to a threshold detector. Capture is verified when the multiplied signal experiences a positive voltage spike that exceeds a predetermined threshold in the threshold detector.
摘要翻译： 具有两个双极性引线的心脏起搏器，一个心房，一个心室，每个具有TIP和RING电极，配置为在两个腔室中用于常规双极起搏/感测。 起搏器中的切换电路可操作以从各种可能的感测配置中进行选择，包括在相应的起搏/感测引线的环形电极之间进行感测的一种配置。 优选地，在每个室中，从相应的末端电极以常规单极配置进行起搏。 “环到环”EGM信号被应用于滤波和EGM放大器电路，然后提供给遥测系统以传输到外部接收机。 环到环的EGM信号具有常规心内信号的高分辨率特性，并且相对不受当相同引线用于起搏和感测时产生的后电位和组织极化效应的影响。 另外，环到环EGM信号是心房和心室电信号的复合物，因此具有与表面ECGS相似的外观。 在所公开的实施例中，提供单独的心房和心室EGM放大器，其中心房EGM放大器接收常规心房单极性感测信号，并且心室EGM放大器接收常规心室单极性感测信号。 来自相应的心房和心室EGM放大器的输出被代数乘以，并且相乘的信号被施加到阈值检测器。 当倍增的信号在阈值检测器中经历超过预定阈值的正电压尖峰时，验证捕获。
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公开(公告)号：US07209790B2
公开(公告)日：2007-04-24
申请号：US10722891
申请日：2003-11-26
IPC分类号： A61N1/08
CPC分类号： A61N1/37252 , H04B1/385 , H04B1/401 , Y10S128/903
摘要： The invention is directed to a programmer for communication with different medical devices that utilize different telemetry communication techniques. The programmer receives telemetry signals from a given medical device, and selects an appropriate communication mode, which can be pre-programmed into the programmer as one of a plurality of possible communication modes. The programmer can configure itself for communication with a given medical device based on the telemetry signal it receives. Specifically the programmer is implemented as a software based, power efficient receiver/transmitter based upon an inexpensive, simple motor-controller DSP.
摘要翻译： 本发明涉及一种用于与使用不同遥测通信技术的不同医疗设备进行通信的编程器。 编程器从给定的医疗设备接收遥测信号，并且选择适当的通信模式，其可以作为多种可能的通信模式之一被预先编程到编程器中。 编程人员可以根据其接收的遥测信号，将其自身配置为与给定医疗设备进行通信。 具体地说，程序员被实现为基于基于软件的功率效率接收器/发射机，其基于廉价的简单的电动机控制器DSP。
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10.发明授权Implantable medical device using audible sound communication to provide warnings 有权可植入医疗器械采用声音通讯提供警告
公开(公告)号：US6067473A
公开(公告)日：2000-05-23
申请号：US282594
申请日：1999-03-31
CPC分类号： A61N1/37258
摘要： Methods and apparatus for interrogation of implantable medical device (IMD) information, including programmed parameter values, operating modes and programmed changes thereof and data stored in the IMD, by emission of audible sounds by the IMD are disclosed. The IMD includes an audio transducer that emits audible sounds including voiced statements or musical tones stored in analog memory correlated to a programming or interrogation operating algorithm or to a warning trigger event. The audible sounds can comprise the sole uplink transmission or may augment the contemporaneous uplink RF transmission of stored data, and/or programmed operating modes and parameters and/or device operations and states in an interrogation or during programming. To conserve energy, the audible sounds accompanying interrogation and programming of the IMD are at a low volume that preferably cannot be heard without use of an external audio amplifier or stethoscope. Voiced statements warning of battery energy depletion or imminent delivery of a therapy are emitted at a higher volume that is sufficient to be heard by the patient, so that the patient can take appropriate action. The volume of audible sounds confirming programmed changes made by a patient using a limited function programmer or magnet is also increased so that the patient can hear them.
摘要翻译： 公开了通过IMD发出可听见的声音来询问可植入医疗装置（IMD）信息的方法和装置，其中包括编程参数值，操作模式及其编程改变以及存储在IMD中的数据。 IMD包括音频换能器，其发射可听声音，包括存储在与编程或询问操作算法相关的模拟存储器中的语音或音调，或者到警告触发事件。 可听见的声音可以包括唯一的上行链路传输，或者可以在询问中或在编程期间增加存储数据的同时期上行链路RF传输和/或编程的操作模式和参数和/或设备操作和状态。 为了节省能量，伴随着IMD的询问和编程的可听见的声音处于较低的音量，最好在不使用外部音频放大器或听诊器的情况下听不到声音。 电池能量消耗或治疗即将发送的声明声明以足以由患者听到的较高音量发出，以便患者能够采取适当的动作。 使用有限功能的编程器或磁铁确认病人进行的编程改变的可听见声音的音量也增加，以便患者可以听到它们的声音。
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