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公开(公告)号：US20090195688A1
公开(公告)日：2009-08-06
申请号：US12422363
申请日：2009-04-13
IPC分类号： H04N5/225
CPC分类号： G02B21/244 , G02B21/002 , G02B21/245 , G02B21/365
摘要： In an imaging device having an objective and a stage for holding a sample to be imaged, a method for autofocusing is presented. The method includes determining a measured focus value corresponding to at least a first of a plurality of logical image segments. Further, the method includes imaging the first logical image segment using the measured focus value. The method also includes determining a predicted focus value for a second of the plurality of logical image segments using the measured focus value and a stored focus variation parameter. In addition, the method includes imaging the second logical image segment using the predicted focus value.
摘要翻译： 在具有用于保持要成像的样品的目标和阶段的成像装置中，提出了一种用于自动聚焦的方法。 该方法包括确定对应于多个逻辑图像片段中的至少第一个的测量焦点值。 此外，该方法包括使用测量的聚焦值对第一逻辑图像片段进行成像。 该方法还包括使用测量的聚焦值和存储的聚焦变化参数来确定多个逻辑图像片段中的第二个的预测聚焦值。 此外，该方法包括使用预测的聚焦值来成像第二逻辑图像片段。
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公开(公告)号：US08878923B2
公开(公告)日：2014-11-04
申请号：US12422363
申请日：2009-04-13
IPC分类号： H04N5/225
CPC分类号： G02B21/244 , G02B21/002 , G02B21/245 , G02B21/365
摘要： In an imaging device having an objective and a stage for holding a sample to be imaged, a method for autofocusing is presented. The method includes determining a measured focus value corresponding to at least a first of a plurality of logical image segments. Further, the method includes imaging the first logical image segment using the measured focus value. The method also includes determining a predicted focus value for a second of the plurality of logical image segments using the measured focus value and a stored focus variation parameter. In addition, the method includes imaging the second logical image segment using the predicted focus value.
摘要翻译： 在具有用于保持要成像的样品的目标和阶段的成像装置中，提出了一种用于自动聚焦的方法。 该方法包括确定对应于多个逻辑图像片段中的至少第一个的测量焦点值。 此外，该方法包括使用测量的聚焦值对第一逻辑图像片段进行成像。 该方法还包括使用测量的聚焦值和存储的聚焦变化参数来确定多个逻辑图像片段中的第二个的预测聚焦值。 此外，该方法包括使用预测的聚焦值来成像第二逻辑图像片段。
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公开(公告)号：US20080266440A1
公开(公告)日：2008-10-30
申请号：US11843754
申请日：2007-08-23
申请人： Siavash Yazdanfar , Robert John Filkins , Elizabeth Lokenberg Dixon , Walter Vincent Dixon , Krenar Tasimi , Kevin Bernard Kenny
发明人： Siavash Yazdanfar , Robert John Filkins , Elizabeth Lokenberg Dixon , Walter Vincent Dixon , Krenar Tasimi , Kevin Bernard Kenny
CPC分类号： G02B21/244 , G02B21/365
摘要： A method of autofocusing includes capturing first, second and third images of a sample, at respective first, second and third sample distances and respective first, second and third lateral positions determined with respect to an objective; determining a quantitative characteristic for the first, second and third images; determining a primary sample distance based upon at least the quantitative characteristics for the first, second, and third images; and capturing a primary image of the sample at the primary sample distance and at a primary lateral position that is offset from the first, second and third lateral positions.
摘要翻译： 自动对焦的方法包括：以相对于目标确定的各自的第一，第二和第三采样距离以及相应的第一，第二和第三横向位置捕获样本的第一，第二和第三图像; 确定第一，第二和第三图像的定量特性; 至少基于第一，第二和第三图像的定量特性来确定主样本距离; 以及在所述主要采样距离处和在偏离所述第一，第二和第三横向位置的主横向位置处捕获所述样本的主要图像。
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公开(公告)号：US08179432B2
公开(公告)日：2012-05-15
申请号：US11843754
申请日：2007-08-23
申请人： Siavash Yazdanfar , Robert John Filkins , Elizabeth Lockenberg Dixon , Walter Vincent Dixon, legal representative , Krenar Tasimi , Kevin Bernard Kenny
发明人： Siavash Yazdanfar , Robert John Filkins , Elizabeth Lockenberg Dixon , Krenar Tasimi , Kevin Bernard Kenny
CPC分类号： G02B21/244 , G02B21/365
摘要： A method of autofocusing includes capturing first, second and third images of a sample, at respective first, second and third sample distances and respective first, second and third lateral positions determined with respect to an objective; determining a quantitative characteristic for the first, second and third images; determining a primary sample distance based upon at least the quantitative characteristics for the first, second, and third images; and capturing a primary image of the sample at the primary sample distance and at a primary lateral position that is offset from the first, second and third lateral positions.
摘要翻译： 自动对焦的方法包括：以相对于目标确定的各自的第一，第二和第三采样距离以及相应的第一，第二和第三横向位置捕获样本的第一，第二和第三图像; 确定第一，第二和第三图像的定量特性; 至少基于第一，第二和第三图像的定量特性来确定主样本距离; 以及在所述主要采样距离处和在偏离所述第一，第二和第三横向位置的主横向位置处捕获所述样本的主要图像。
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5.发明申请METHODS AND SYSTEMS OF OPTICAL IMAGING FOR TARGET DETECTION IN A SCATTERING MEDIUM 有权光学成像技术在散射介质中的目标检测方法与系统公开(公告)号：US20120128264A1
公开(公告)日：2012-05-24
申请号：US12952359
申请日：2010-11-23
CPC分类号： A61B5/0059 , A61B5/0064
摘要： A method for enhancing contrast in fluorescence imaging is provided. The method comprises providing a patterned illumination source for illuminating one or more regions corresponding to a scan step, scanning at least a portion of a surface of a subject using a plurality of scan steps, acquiring image frames corresponding to two or more scan steps, deducting a background fluorescence from the image frames corresponding to the two or more scan steps to form one or more processed image frames, and reconstructing an image using one or more of the processed image frames.
摘要翻译： 提供了一种增强荧光成像对比度的方法。 该方法包括提供用于照亮与扫描步骤相对应的一个或多个区域的图案化照明源，使用多个扫描步骤扫描对象的表面的至少一部分，获取对应于两个或更多个扫描步骤的图像帧，扣除 来自对应于两个或更多个扫描步骤的图像帧的背景荧光，以形成一个或多个经处理的图像帧，以及使用一个或多个处理后的图像帧重建图像。
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公开(公告)号：US20110043916A1
公开(公告)日：2011-02-24
申请号：US12543785
申请日：2009-08-19
CPC分类号： G02B23/243
摘要： A wide angle hybrid refractive-diffractive endoscope objective is provided. The objective comprises a negative meniscus lens having a first surface and a second surface; a stop adjacent to the negative meniscus lens; a positive lens adjacent to the negative lens and having a first surface and a second surface; and a hybrid refractive-diffractive element adjacent to the positive lens and having a first surface and a second surface, wherein one of the first surface, or the second surface comprises a diffractive surface, wherein the objective has an effective focal length in a range from about 0.8 mm to about 1.6 mm.
摘要翻译： 提供广角混合折射衍射内窥镜目的。 该目的包括具有第一表面和第二表面的负凹凸透镜; 靠近负弯月透镜的止动件; 与透镜相邻并具有第一表面和第二表面的正透镜; 以及与所述正透镜相邻并且具有第一表面和第二表面的混合折射衍射元件，其中所述第一表面或所述第二表面中的一个包括衍射表面，其中所述物镜具有在以下范围内的有效焦距： 约0.8mm至约1.6mm。
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公开(公告)号：US07824034B2
公开(公告)日：2010-11-02
申请号：US11857581
申请日：2007-09-19
CPC分类号： A61B3/1216 , A61B3/14
摘要： An iris imaging system is provided. The iris imaging system includes at least one light source configured to illuminate an iris at a spectrum of light. The iris imaging system also includes at least one image capturing device including at least one of an indium-gallium-arsenide, lead sulphide, and lead selenide based detector and configured to capture an image of the iris via light reflected from the iris at the spectrum. The device is further configured to provide a signal representing one or more features of the iris in response to the light reflected from the iris.
摘要翻译： 提供虹膜成像系统。 虹膜成像系统包括至少一个被配置为以光谱照射虹膜的光源。 虹膜成像系统还包括至少一个图像捕获装置，其包括砷化铟镓，硫化铅和基于硒化铅的检测器中的至少一种，并被配置为通过光谱从光谱反射的光线捕获虹膜的图像 。 该装置还被配置为响应于从虹膜反射的光来提供表示虹膜的一个或多个特征的信号。
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8.发明授权Endoscope objective lens with large entrance pupil diameter and high numerical aperture 有权具有大入口光瞳直径和高数值孔径的内窥镜物镜公开(公告)号：US07821720B2
公开(公告)日：2010-10-26
申请号：US12125512
申请日：2008-05-22
申请人： Xinghua Wang , Siavash Yazdanfar
发明人： Xinghua Wang , Siavash Yazdanfar
CPC分类号： G02B23/243
摘要： An endoscope objective lens for collecting combined bright field (white light) and fluorescence images includes a negative lens group, a stop, and a positive lens group. The lens has a combination of large entrance pupil diameter (≧0.4 mm) for efficiently collecting weak fluorescence light, large ratio between the entrance pupil diameter and the maximum outside diameter (Dentrance/Dmax larger than 0.2), large field of view (FFOV≧120°) and favorably corrected spherical, lateral chromatic and Petzval field curvature for both visible and near infrared wavelengths.
摘要翻译： 用于收集组合亮场（白光）和荧光图像的内窥镜物镜包括负透镜组，光阑和正透镜组。 透镜具有大的入射光瞳直径（≥0.4mm）的组合，用于有效地收集弱荧光，入射光瞳直径和最大外径之间的大比（Dentrance / Dmax大于0.2），大视场（FFOV≥ 120°），并且对于可见光和近红外波长都有良好校正的球面，横向色度和Petzval场曲率。
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公开(公告)号：US20100110572A1
公开(公告)日：2010-05-06
申请号：US12263673
申请日：2008-11-03
IPC分类号： G02B5/22
CPC分类号： G02B5/189 , G02B5/20 , G02B5/201 , G02B7/006 , G02B26/008 , G02B26/0875
摘要： Provided herein are devices, systems, and methods for multimodal optical imaging. The devices include a filter assembly that is capable of rotary action during real time image acquisition. The systems include such filter assemblies, which are detachable or integrated in the systems. The methods include techniques for capturing image targets using multiple light sources such as white light and fluorescent light.
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公开(公告)号：US20090244521A1
公开(公告)日：2009-10-01
申请号：US12059819
申请日：2008-03-31
IPC分类号： G01N21/00
CPC分类号： G01N21/6456 , G01N2021/6471 , G01N2021/6484 , G01N2021/6493
摘要： A technique is provided for multi-mode optical imaging. The technique includes directing a visible light and an excitation light towards a specimen. The excitation light is configured to induce luminescence in the specimen. The technique also includes detecting visible light scattered or reflected from the specimen and luminescent light emitted via luminescence simultaneously via a single detector.
摘要翻译： 提供了一种多模光学成像技术。 该技术包括将可见光和激发光引向样本。 激发光被配置为在样品中诱导发光。 该技术还包括通过单个检测器同时检测从样品散射或反射的可见光和通过发光发射的发光。
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