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    Devices and Methods for Perfusing an Organ
    2.
    发明申请
    Devices and Methods for Perfusing an Organ 审中-公开
    用于灌注器官的装置和方法

    公开(公告)号：US20090018526A1

    公开(公告)日：2009-01-15

    申请号：US11996416

    申请日：2006-08-25

    申请人： John Melmouth Power ,  Mark L. Mathis ,  David Martin Kaye ,  Adam Lucas Bilney

    发明人： John Melmouth Power ,  Mark L. Mathis ,  David Martin Kaye ,  Adam Lucas Bilney

    IPC分类号： A61M25/01 ,  A61F2/84

    CPC分类号： A61M25/01 ,  A61F2/82 ,  A61M25/09 ,  A61M25/10 ,  A61M29/02 ,  A61M2025/09183 ,  A61M2025/1052

    摘要： The present invention provides devices and methods for use in the perfusion of organs and anatomical regions. In one aspect the present method provides a percutaneously deliverable device for supporting a vessel in a human or animal subject including means for supporting the vessel during delivery of a fluid thereto or collection of a fluid therefrom. In another aspect the invention provides a method for delivery or collection of a fluid to or from an organ or anatomical region in a human or animal subject, the method including the step of supporting a vessel associated with the organ or anatomical region. The devices and methods may be used to deliver, remove or recirculate a therapeutic agent to an organ or anatomical region.

    摘要翻译： 本发明提供了用于器官和解剖区域灌注中的装置和方法。 在一个方面，本方法提供了一种用于在人或动物对象中支撑血管的经皮递送装置，包括用于在输送流体或从其收集流体的过程中支撑血管的装置。 在另一方面，本发明提供了一种用于将流体递送或收集于人或动物受试者中的器官或解剖区域的方法，所述方法包括支撑与器官或解剖区域相关联的血管的步骤。 所述装置和方法可用于递送，移除或再循环治疗剂至器官或解剖区域。

    Device and Method for Modifying the Shape of a Body Organ
    4.
    发明申请
    Device and Method for Modifying the Shape of a Body Organ 审中-公开
    修饰身体器官形状的装置和方法

    公开(公告)号：US20120197389A1

    公开(公告)日：2012-08-02

    申请号：US13443709

    申请日：2012-04-10

    申请人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter ,  Cruz Beeson ,  Leonard Kowalsky

    发明人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter ,  Cruz Beeson ,  Leonard Kowalsky

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2451 ,  A61F2250/001 ,  A61F2250/0059

    摘要： An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.

    摘要翻译： 血管内支持装置包括支撑件或再生线，近端锚和远端锚。 支撑线接合血管壁以改变邻近其中放置血管内支架的血管的组织的形状。 锚和支撑线被设计成使得放置支撑件的容器保持打开，并且如果需要可以被其他装置访问。 该装置为在血管内流动的血液提供最小的金属表面积，以限制血栓形成。 锚固件可以锁定到位以将支撑件固定在容器内。

    Device and method for modifying the shape of a body organ
    5.
    发明授权
    Device and method for modifying the shape of a body organ 有权
    用于改变身体器官形状的装置和方法

    公开(公告)号：US08172898B2

    公开(公告)日：2012-05-08

    申请号：US12719758

    申请日：2010-03-08

    申请人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter ,  Cruz Beeson ,  Leonard Kowalsky

    发明人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter ,  Cruz Beeson ,  Leonard Kowalsky

    IPC分类号： A61F2/24 ,  A61F2/06

    CPC分类号： A61F2/2451 ,  A61F2250/001 ,  A61F2250/0059

    摘要： An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.

    摘要翻译： 血管内支持装置包括支撑件或再生线，近端锚和远端锚。 支撑线接合血管壁以改变邻近其中放置血管内支架的血管的组织的形状。 锚和支撑线被设计成使得放置支撑件的容器保持打开，并且如果需要可以被其他装置访问。 该装置为在血管内流动的血液提供最小的金属表面积，以限制血栓形成。 锚固件可以锁定到位以将支撑件固定在容器内。

    Device and Method for Modifying the Shape of a Body Organ
    6.
    发明申请
    Device and Method for Modifying the Shape of a Body Organ 有权
    修饰身体器官形状的装置和方法

    公开(公告)号：US20100168847A1

    公开(公告)日：2010-07-01

    申请号：US12719758

    申请日：2010-03-08

    申请人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter ,  Cruz Beeson ,  Leonard Kowalsky

    发明人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter ,  Cruz Beeson ,  Leonard Kowalsky

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2451 ,  A61F2250/001 ,  A61F2250/0059

    摘要： An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.

    摘要翻译： 血管内支持装置包括支撑件或再生线，近端锚和远端锚。 支撑线接合血管壁以改变邻近其中放置血管内支架的血管的组织的形状。 锚和支撑线被设计成使得放置支撑件的容器保持打开，并且如果需要可以被其他装置访问。 该装置为在血管内流动的血液提供最小的金属表面积，以限制血栓形成。 锚固件可以锁定到位以将支撑件固定在容器内。

    Device and method for modifying the shape of a body organ
    7.
    发明授权
    Device and method for modifying the shape of a body organ 有权
    用于改变身体器官形状的装置和方法

    公开(公告)号：US07674287B2

    公开(公告)日：2010-03-09

    申请号：US11467105

    申请日：2006-08-24

    申请人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter ,  Cruz Beeson ,  Leonard Kowalsky

    发明人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter ,  Cruz Beeson ,  Leonard Kowalsky

    IPC分类号： A61F2/24 ,  A61F2/06

    CPC分类号： A61F2/2451 ,  A61F2250/001 ,  A61F2250/0059

    摘要： An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.

    摘要翻译： 血管内支持装置包括支撑件或再生线，近端锚和远端锚。 支撑线接合血管壁以改变邻近其中放置血管内支架的血管的组织的形状。 锚和支撑线被设计成使得放置支撑件的容器保持打开，并且如果需要可以被其他装置访问。 该装置为在血管内流动的血液提供最小的金属表面积，以限制血栓形成。 锚固件可以锁定到位以将支撑件固定在容器内。

    Anchor and pull mitral valve device and method
    8.
    发明授权
    Anchor and pull mitral valve device and method 有权
    锚和拉二尖瓣装置及方法

    公开(公告)号：US06908478B2

    公开(公告)日：2005-06-21

    申请号：US10011867

    申请日：2001-12-05

    申请人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter

    发明人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter

    IPC分类号： A61F2/24 ,  A61F2/06

    CPC分类号： A61F2/2451 ,  A61F2/2466

    摘要： A device, system, and method effects mitral valve annulus geometry of a heart. The device includes a first anchor configured to be positioned within and fixed to the coronary sinus of the heart adjacent the mitral valve annulus within the heart. A cable is fixed to the first anchor and extends proximately therefrom and slidingly through a second anchor which is positioned and fixed in the heart proximal to the first anchor. A lock locks the cable to the second anchor when tension is applied to the cable for effecting the mitral valve annulus geometry.

    摘要翻译： 一种装置，系统和方法影响心脏的二尖瓣环形几何。 该装置包括构造成定位在心脏内邻近二尖瓣环的心脏的冠状窦内并固定到其的冠状窦的第一锚。 电缆固定到第一锚固件并且从其向近侧延伸并且滑动地穿过定位并固定在靠近第一锚固件的心脏中的第二锚固件。 当拉索施加到电缆以实现二尖瓣环形几何时，锁将电缆锁定到第二锚定器。