公开(公告)号：US20080027407A1

公开(公告)日：2008-01-31

申请号：US11597349

申请日：2006-11-20

申请人： David Miller ,  Todd Alamin ,  Peter Campbell

发明人： David Miller ,  Todd Alamin ,  Peter Campbell

IPC分类号： A61M31/00

CPC分类号： A61B17/3478 ,  A61B17/3421 ,  A61B17/3472 ,  A61B2017/00261 ,  A61B2017/00469 ,  A61B2017/3488

摘要： Methods, devices and systems facilitate diagnosis, and in some cases treatment, of back pain originating in intervertebral discs. Methods generally involve introducing one or more substances into one or more discs using a catheter device. In one embodiment, a patient assumes a position that causes back pain, and a substance such as an anesthetic or analgesic is introduced into the disc to determine whether the substance relieves the pain. Injections into multiple discs may optionally be performed, to help pinpoint a disc as a source of the patient's pain. In some embodiments, the catheter device is left in place, and possibly coupled with another implantable device, to provide treatment of one or more discs. A catheter device includes at least one anchoring member for maintaining a distal portion of the catheter within a disc.

摘要翻译： 方法，装置和系统便于在椎间盘中产生的背部疼痛的诊断以及在某些情况下治疗。 方法通常包括使用导管装置将一种或多种物质引入一个或多个盘中。 在一个实施方案中，患者承担引起背部疼痛的位置，并且将诸如麻醉剂或镇痛剂的物质引入椎间盘以确定该物质是否释放疼痛。 可以可选地执行到多个盘中的注射，以帮助确定光盘作为患者疼痛的来源。 在一些实施例中，导管装置留在原位，并且可能与另一种可植入装置联接，以提供对一个或多个盘的治疗。 导管装置包括用于将导管的远侧部分保持在盘内的至少一个锚固构件。

公开(公告)号：US20080009828A1

公开(公告)日：2008-01-10

申请号：US11616212

申请日：2006-12-26

申请人： David Miller ,  Todd Alamin ,  Peter Campbell

发明人： David Miller ,  Todd Alamin ,  Peter Campbell

IPC分类号： A61M31/00 ,  A61F2/44

CPC分类号： A61B17/3478 ,  A61B17/3421 ,  A61B17/3472 ,  A61B2017/00261 ,  A61B2017/00469 ,  A61B2017/3488

摘要： Methods, devices and systems facilitate diagnosis, and in some cases treatment, of back pain originating in intervertebral discs. Methods generally involve introducing one or more substances into one or more discs using a catheter device. In one embodiment, a patient assumes a position that causes back pain, and a substance such as an anesthetic or analgesic is introduced into the disc to determine whether the substance relieves the pain. Injections into multiple discs may optionally be performed, to help pinpoint a disc as a source of the patient's pain. In some embodiments, the catheter device is left in place, and possibly coupled with another implantable device, to provide treatment of one or more discs. A catheter device includes at least one anchoring member for maintaining a distal portion of the catheter within a disc.

摘要翻译： 方法，装置和系统便于在椎间盘中产生的背部疼痛的诊断以及在某些情况下治疗。 方法通常包括使用导管装置将一种或多种物质引入一个或多个盘中。 在一个实施方案中，患者承担引起背部疼痛的位置，并且将诸如麻醉剂或镇痛剂的物质引入椎间盘以确定该物质是否释放疼痛。 可以可选地执行到多个盘中的注射，以帮助确定光盘作为患者疼痛的来源。 在一些实施例中，导管装置留在原位，并且可能与另一种可植入装置联接，以提供对一个或多个盘的治疗。 导管装置包括用于将导管的远侧部分保持在盘内的至少一个锚固构件。

公开(公告)号：US20080021435A1

公开(公告)日：2008-01-24

申请号：US11616215

申请日：2006-12-26

申请人： David Miller ,  Todd Alamin ,  Peter Campbell

发明人： David Miller ,  Todd Alamin ,  Peter Campbell

IPC分类号： A61M31/00 ,  A61F7/00

CPC分类号： A61B17/3478 ,  A61B17/3421 ,  A61B17/3472 ,  A61B2017/00261 ,  A61B2017/00469 ,  A61B2017/3488

摘要： Methods, devices and systems facilitate diagnosis, and in some cases treatment, of back pain originating in intervertebral discs. Methods generally involve introducing one or more substances into one or more discs using a catheter device. In one embodiment, a patient assumes a position that causes back pain, and a substance such as an anesthetic or analgesic is introduced into the disc to determine whether the substance relieves the pain. Injections into multiple discs may optionally be performed, to help pinpoint a disc as a source of the patient's pain. In some embodiments, the catheter device is left in place, and possibly coupled with another implantable device, to provide treatment of one or more discs. A catheter device includes at least one anchoring member for maintaining a distal portion of the catheter within a disc.

公开(公告)号：US20080009826A1

公开(公告)日：2008-01-10

申请号：US11616219

申请日：2006-12-26

申请人： David Miller ,  Todd Alamin ,  Peter Campbell

发明人： David Miller ,  Todd Alamin ,  Peter Campbell

IPC分类号： A61M25/00 ,  A61F2/44

CPC分类号： A61B17/3478 ,  A61B17/3421 ,  A61B17/3472 ,  A61B2017/00261 ,  A61B2017/00469 ,  A61B2017/3488

摘要： Methods, devices and systems facilitate diagnosis, and in some cases treatment, of back pain originating in intervertebral discs. Methods generally involve introducing one or more substances into one or more discs using a catheter device. In one embodiment, a patient assumes a position that causes back pain, and a substance such as an anesthetic or analgesic is introduced into the disc to determine whether the substance relieves the pain. Injections into multiple discs may optionally be performed, to help pinpoint a disc as a source of the patient's pain. In some embodiments, the catheter device is left in place, and possibly coupled with another implantable device, to provide treatment of one or more discs. A catheter device includes at least one anchoring member for maintaining a distal portion of the catheter within a disc.

公开(公告)号：US20050234425A1

公开(公告)日：2005-10-20

申请号：US10825961

申请日：2004-04-16

申请人： David Miller ,  Todd Alamin ,  Peter Campbell

发明人： David Miller ,  Todd Alamin ,  Peter Campbell

IPC分类号： A61B17/00 ,  A61B17/34 ,  A61M31/00

CPC分类号： A61B17/3478 ,  A61B17/3421 ,  A61B17/3472 ,  A61B2017/00261 ,  A61B2017/00469 ,  A61B2017/3488

摘要： Methods, devices and systems facilitate diagnosis, and in some cases treatment, of back pain originationg in intervertebral discs. Methods generally involve introducing one or more substances into one or more discs using a catheter device. In one embodiments, a patient assumes a position that causes back pain, and a substance such as an anesthetic or analgesic is introduced into the disc to determine whether the substance relieves the pain. Injections into multiple discs may optionally be performed, to help pinpoint a disc as a sources of the patient's pain. In some embodiments, the catheter device is left in place, and possibly coupled with another implantable device, to provide treatment of one or more discs. A catheter device includes at least one anchoring member for maintaining a distal portion of the catheter within a disc.

摘要翻译： 方法，装置和系统便于在椎间盘中诊断背部疼痛，并在某些情况下治疗。 方法通常包括使用导管装置将一种或多种物质引入一个或多个盘中。 在一个实施方案中，患者承担引起背部疼痛的位置，并且将诸如麻醉剂或止痛剂的物质引入椎间盘中以确定该物质是否释放疼痛。 可以可选地执行到多个盘中的注射，以帮助确定光盘作为患者疼痛的来源。 在一些实施例中，导管装置留在原位，并且可能与另一种可植入装置联接，以提供对一个或多个盘的治疗。 导管装置包括用于将导管的远侧部分保持在盘内的至少一个锚固构件。

公开(公告)号：US20220143082A1

公开(公告)日：2022-05-12

申请号：US17580419

申请日：2022-01-20

申请人： Todd Alamin ,  Avram Allan Edidin ,  Hugues Malandain ,  Healey Montague-Alamin

发明人： Todd Alamin ,  Avram Allan Edidin ,  Hugues Malandain ,  Healey Montague-Alamin

IPC分类号： A61K35/13 ,  C12M1/00 ,  C12N5/09

摘要： Tumor tissue, including soft and/or bony tissue, are harvested from a subject and morcellated. The morcellated tissue is placed in a cartridge which is placed in a containment chamber of a tumor tissue processing device. Cancer cells in the morcellated tumor tissue are destroyed without destroying tumor antigens therein. These cells are destroyed cryogenically by exposing the cartridge to a cooling fluid such as liquid nitrogen, optionally with a warming cycle, and optionally with more than one freezing/thawing cycle. The treated tissue and/or cells are then extracted from the cartridge and reintroduced to the subject after they have reached a threshold condition. The treated tissue and/or cells can be reintroduced via a containment sleeve or a reimplantation bag.

公开(公告)号：US09295499B2

公开(公告)日：2016-03-29

申请号：US13889581

申请日：2013-05-08

申请人： Todd Alamin ,  Ian Bennett ,  Colin Cahill ,  Louis Fielding ,  Manish Kothari ,  Jeffrey Schwardt

发明人： Todd Alamin ,  Ian Bennett ,  Colin Cahill ,  Louis Fielding ,  Manish Kothari ,  Jeffrey Schwardt

IPC分类号： A61B17/70 ,  A61B17/84

CPC分类号： A61B17/7065 ,  A61B17/7055 ,  A61B17/7062 ,  A61B17/842

摘要： A spinal implant for limiting flexion of the spine includes a tether structure for encircling adjacent spinal processes. Usually, a pair of compliance members will be provided as part of the tether structure for elastically limiting flexion while permitting an extension. A cross-member is provided between the compliance member or other portions of the tether structure to stabilize the tether structure and prevent misalignment after implantation.

公开(公告)号：US20120209328A1

公开(公告)日：2012-08-16

申请号：US13455917

申请日：2012-04-25

申请人： Todd Alamin ,  Ian Bennett ,  Louis Fielding ,  Colin Cahill ,  Manish Kothari

发明人： Todd Alamin ,  Ian Bennett ,  Louis Fielding ,  Colin Cahill ,  Manish Kothari

IPC分类号： A61B17/70 ,  A61B17/88

CPC分类号： A61B17/7062 ,  A61B17/7055 ,  A61B17/842

摘要： Spinous process constraint structures include a first attachment element for placement over a first spinous process and a second attachment element for placement over a second spinous process. The attachment elements are joined by a single connector which may optionally include a compliance member for providing controlled elasticity between the spinous processes.

摘要翻译： 旋转过程约束结构包括用于放置在第一棘突上的第一附接元件和用于放置在第二棘突上的第二附接元件。 附接元件通过单个连接器连接，该连接器可以可选地包括用于在棘突之间提供受控弹性的柔顺构件。

公开(公告)号：US20120123482A1

公开(公告)日：2012-05-17

申请号：US13340483

申请日：2011-12-29

申请人： Louis Fielding ,  Ian Bennett ,  Colin Cahill ,  Pat Arensdorf ,  Ralph Crisostomo ,  Todd Alamin

发明人： Louis Fielding ,  Ian Bennett ,  Colin Cahill ,  Pat Arensdorf ,  Ralph Crisostomo ,  Todd Alamin

IPC分类号： A61B17/88

CPC分类号： A61B17/7062

摘要： A spinal implant system for restricting flexion of a spine includes an elongate band proportioned to engage at least two spinous processes. During use, the band is positioned engaging the spinous processes at a spinal segment of interest, where it restricts flexion at the segment. The length and tension of the band may be adjustable following to implantation using percutaneous or transcutaneous means.

摘要翻译： 用于限制脊柱弯曲的脊柱植入系统包括成比例的细长带以接合至少两个棘突。 在使用期间，带被定位成与感兴趣的脊髓部分处的棘突接合，其中它限制了该部分的屈曲。 在使用经皮或经皮手段进行植入之后，带的长度和张力可以是可调节的。

公开(公告)号：US07905874B2

公开(公告)日：2011-03-15

申请号：US11616222

申请日：2006-12-26

申请人： David R. Miller ,  Todd Alamin ,  Peter F. Campbell

发明人： David R. Miller ,  Todd Alamin ,  Peter F. Campbell

IPC分类号： A61M31/00

CPC分类号： A61B17/3478 ,  A61B17/3421 ,  A61B17/3472 ,  A61B2017/00261 ,  A61B2017/00469 ,  A61B2017/3488

摘要： Methods, devices and systems facilitate diagnosis, and in some cases treatment, of back pain originating in intervertebral discs. Methods generally involve introducing one or more substances into one or more discs using a catheter device. In one embodiment, a patient assumes a position that causes back pain, and a substance such as an anesthetic or analgesic is introduced into the disc to determine whether the substance relieves the pain. Injections into multiple discs may optionally be performed, to help pinpoint a disc as a source of the patient's pain. In some embodiments, the catheter device is left in place, and possibly coupled with another implantable device, to provide treatment of one or more discs. A catheter device includes at least one anchoring member for maintaining a distal portion of the catheter within a disc.

摘要翻译： 方法，装置和系统便于在椎间盘中产生的背部疼痛的诊断以及在某些情况下治疗。 方法通常包括使用导管装置将一种或多种物质引入一个或多个盘中。 在一个实施方案中，患者承担引起背部疼痛的位置，并且将诸如麻醉剂或镇痛剂的物质引入椎间盘以确定该物质是否释放疼痛。 可以可选地执行到多个盘中的注射，以帮助确定光盘作为患者疼痛的来源。 在一些实施例中，导管装置留在原位，并且可能与另一种可植入装置联接，以提供对一个或多个盘的治疗。 导管装置包括用于将导管的远侧部分保持在盘内的至少一个锚固构件。