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公开(公告)号：US20120088659A1
公开(公告)日：2012-04-12
申请号：US13376191
申请日：2010-06-04
摘要： Compositions for the controlled delivery of active ingredients, for example, drugs, cosmetic materials, and agricultural materials. The compositions include a multiplicity of particles, each of the particles comprising (1) a microstructure comprising a semicrystalline polymer which has a peak melting temperature, Tp, of at least 20° C., and (2) the active ingredient. The microstructure comprises (i) crystalline domains of the semicrystalline polymer, the crystalline domains being separate from each other, and (ii) amorphous domains of the semicrystalline polymer, the amorphous domains providing a multiplicity of tortuous paths between the crystalline domains. At least part of the active ingredient is present in the amorphous domains. One of many valuable uses for the compositions is to provide a coating on a seed, for example a coating containing one or more of an insecticide, a fungicide, a nutrient, a biotic, a growth regulator and an herbicide.
摘要翻译： 用于控制递送活性成分的组合物，例如药物，化妆品材料和农业材料。 组合物包括多个颗粒，每个颗粒包含（1）包含半结晶聚合物的微结构，其具有至少20℃的峰值熔融温度Tp，和（2）活性成分。 微结构包括（i）半结晶聚合物的结晶域，结晶域彼此分离，和（ii）半结晶聚合物的无定形区域，非晶畴在晶畴之间提供多个曲折的路径。 至少部分活性成分存在于无定形区域中。 组合物的许多有价值的用途之一是在种子上提供涂层，例如包含杀虫剂，杀真菌剂，营养物，生物，生长调节剂和除草剂中的一种或多种的涂层。
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公开(公告)号：US20120082709A1
公开(公告)日：2012-04-05
申请号：US13377566
申请日：2010-06-11
IPC分类号： A61K47/36 , A61K8/02 , A01N25/10 , A61K8/65 , A61K47/42 , A61K47/40 , A61K8/73 , A61K47/08 , A61K9/14
摘要： Compositions for delivering release materials, for example drugs, agricultural materials, other bioactive materials, cosmetic materials, organic or inorganic compounds which take part in or catalyse a chemical reaction, a fragrance-emitting material for a vaporizer, or a lubricating material. The release material is associated with a crystalline carrier. The carrier may be a crystalline polymer containing a plurality of crystalline groups or a crystalline monomer which contains a single crystalline group, the crystalline group preferably comprising a straight chain polymethylene radical containing at least 16 carbon atoms. Some of the carriers are obtained by modifying hyaluronic acid, collagen, gelatin, a polysaccharide, a carbohydrate or cyclodextran. The release material may contain a similar crystalline group, for example may be an active compound which has been modified to introduce a crystalline group.
摘要翻译： 用于输送释放材料的组合物，例如药物，农业材料，其他生物活性材料，化妆品材料，参与或催化化学反应的有机或无机化合物，用于蒸发器的发泡材料或润滑材料。 释放材料与结晶载体结合。 载体可以是含有多个结晶基团的结晶聚合物或含有单一结晶基团的结晶单体，该结晶基团优选包含含有至少16个碳原子的直链多亚甲基基团。 一些载体通过修饰透明质酸，胶原，明胶，多糖，碳水化合物或环糊精得到。 释放材料可以含有相似的结晶基团，例如可以是经修饰以引入结晶基团的活性化合物。
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