Stable NAD/NADH derivatives
    1.
    发明授权
    Stable NAD/NADH derivatives 有权
    稳定的NAD / NADH衍生物

    公开(公告)号:US08809013B2

    公开(公告)日:2014-08-19

    申请号:US12020244

    申请日:2008-01-25

    IPC分类号: C12Q1/32

    CPC分类号: C12Q1/32

    摘要: The present invention provides for stable nicotinamide adenine dinucleotide (NAD/NADH) and nicotinamide adenine dinucleotide phosphate (NADP/NADPH) derivatives of formula (I), enzyme complexes of these derivatives and their use in biochemical detection methods and reagent kits.

    摘要翻译: 本发明提供式(I)的稳定的烟酰胺腺嘌呤二核苷酸(NAD / NADH)和烟酰胺腺嘌呤二核苷酸磷酸(NADP / NADPH)衍生物,这些衍生物的酶复合物及其在生物化学检测方法和试剂盒中的用途。

    Fluorescence spectropscopy in absorbing media
    7.
    发明授权
    Fluorescence spectropscopy in absorbing media 有权
    吸收介质中的荧光分光光度法

    公开(公告)号:US08338118B2

    公开(公告)日:2012-12-25

    申请号:US12368286

    申请日:2009-02-09

    IPC分类号: C12Q1/54

    摘要: The invention relates to processes and devices for detecting an analyte in a sample by fluorescence measurement of a fluorophore, wherein the detection medium which contains a fluorophore or a precursor of the fluorophore is admixed with an absorber whose absorbance spectrum superimposes the fluorescence excitation range of the fluorophore. The system consisting of the fluorophore and the absorber, which is produced in the detection medium, has an altered effective fluorescence excitation range with an altered fluorescence excitation maximum. Illumination with fluorescence excitation light can take place within the range of this altered excitation maximum. The measured signal obtained from determining fluorescence emission exhibits only low dependence on the wavelength of the excitation light.

    摘要翻译: 本发明涉及通过荧光团的荧光测定来检测样品中分析物的方法和装置,其中将含有荧光团或荧光团前体的检测介质与吸收光谱与吸收光谱的荧光激发范围相加 荧光团。 由荧光团和在检测介质中产生的吸收体组成的系统具有改变的有效荧光激发范围,具有改变的荧光激发最大值。 荧光激发光的照明可以在这种改变的激发最大值的范围内进行。 从确定荧光发射获得的测量信号仅显示对激发光的波长的低依赖性。

    Fluorescence spectroscopy in absorbing media
    9.
    发明授权
    Fluorescence spectroscopy in absorbing media 有权
    吸收介质中的荧光光谱

    公开(公告)号:US08501113B2

    公开(公告)日:2013-08-06

    申请号:US12942356

    申请日:2010-11-09

    IPC分类号: G01N33/533

    摘要: The invention relates to processes and devices for detecting an analyte in a sample by fluorescence measurement of a fluorophore, wherein the detection medium which contains a fluorophore or a precursor of the fluorophore is admixed with an absorber whose absorbance spectrum superimposes the fluorescence excitation range of the fluorophore. The system consisting of the fluorophore and the absorber, which is produced in the detection medium, has an altered effective fluorescence excitation range with an altered fluorescence excitation maximum. Illumination with fluorescence excitation light can take place within the range of this altered excitation maximum. The measured signal obtained from determining fluorescence emission exhibits only low dependence on the wavelength of the excitation light.

    摘要翻译: 本发明涉及通过荧光团的荧光测定来检测样品中分析物的方法和装置,其中将含有荧光团或荧光团前体的检测介质与吸收光谱与吸收光谱的荧光激发范围相加 荧光团。 由荧光团和在检测介质中产生的吸收体组成的系统具有改变的有效荧光激发范围,具有改变的荧光激发最大值。 荧光激发光的照明可以在这种改变的激发最大值的范围内进行。 从确定荧光发射获得的测量信号仅显示对激发光的波长的低依赖性。