-
公开(公告)号：US20080200467A1
公开(公告)日：2008-08-21
申请号：US11934698
申请日：2007-11-02
申请人： Dinesh Patel , Richard D. Gless , Heather K. Webb Hsu , Sampath Kumar Anandan , Bhaskar R. Aavula
发明人： Dinesh Patel , Richard D. Gless , Heather K. Webb Hsu , Sampath Kumar Anandan , Bhaskar R. Aavula
IPC分类号： A61K31/5375 , C07C237/00 , A61K31/164 , C07D233/54 , A61P9/00 , A61P3/10 , A61P11/00 , A61K31/4164 , A61K31/445 , C07D295/00
CPC分类号： C07C235/34 , C07C235/26 , C07C235/36 , C07C235/80 , C07C2601/14 , C07C2603/74 , C07D211/58 , C07D211/96 , C07D233/54 , C07D233/58 , C07D295/092 , C07D295/125 , C07D295/13 , C07D295/192 , C07D295/26
摘要： Disclosed are alpha keto amide and alpha hydroxy amide compounds and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and compositions. The compounds, compositions, and methods are useful for treating a variety of sEH mediated diseases, including hypertensive, cardiovascular, inflammatory, pulmonary, and diabetic-related diseases.
摘要翻译： 公开了抑制可溶性环氧化物水解酶（sEH）的α-酮酰胺和α羟基酰胺化合物和组合物，用于制备化合物和组合物的方法以及用这些化合物和组合物治疗患者的方法。 化合物，组合物和方法可用于治疗各种sEH介导的疾病，包括高血压，心血管，炎症，肺和糖尿病相关疾病。
-
公开(公告)号：US20080227780A1
公开(公告)日：2008-09-18
申请号：US11875658
申请日：2007-10-19
IPC分类号： A61K31/5377 , C07D211/98 , C07D413/12 , A61P9/12 , A61K31/4468
CPC分类号： C07D211/58 , C07D211/96 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/06 , C07D417/12
摘要： Disclosed are urea compounds, stereoisomer, or pharmaceutical acceptable salt thereof, and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and compositions. The compounds, compositions, and methods are useful for treating a variety of sEH mediated diseases, including hypertensive, cardiovascular, inflammatory, pulmonary, and diabetic-related diseases.
摘要翻译： 公开了尿素化合物，立体异构体或其药学上可接受的盐，以及抑制可溶性环氧化物水解酶（sEH）的组合物，制备化合物和组合物的方法以及用这些化合物和组合物治疗患者的方法。 化合物，组合物和方法可用于治疗各种sEH介导的疾病，包括高血压，心血管，炎症，肺和糖尿病相关疾病。
-
公开(公告)号：US20080221100A1
公开(公告)日：2008-09-11
申请号：US11875673
申请日：2007-10-19
IPC分类号： A61K31/4468 , C07D413/06 , C07D211/58 , A61K31/4545 , A61P9/00 , A61P11/00 , A61P3/10 , A61P29/00 , A61K31/454 , C07D401/06 , A61K31/5377
CPC分类号： C07D211/58 , C07D211/96 , C07D401/06 , C07D413/06
摘要： Disclosed are urea compounds, stereoisomer, or pharmaceutical acceptable salt thereof, and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and compositions. The compounds, compositions, and methods are useful for treating a variety of sEH mediated diseases, including hypertensive, cardiovascular, inflammatory, pulmonary, and diabetic-related diseases.
-
-
搜索结果
3 条记录 (耗时 0.036 秒)
