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公开(公告)号:US20080199906A1
公开(公告)日:2008-08-21
申请号:US11660461
申请日:2005-08-26
CPC分类号: C07K14/7155 , C12N15/1138
摘要: Described are codon optimized sgp130 encoding nucleic acid molecules as well as a method for the highly efficient recombinant production of sgp130 in mammalian cells or bacteria using a nucleic acid molecule of the invention.
摘要翻译: 描述了密码子优化的sgp130编码核酸分子以及使用本发明的核酸分子在哺乳动物细胞或细菌中高效重组产生sgp130的方法。
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公开(公告)号:US20070270334A1
公开(公告)日:2007-11-22
申请号:US10561874
申请日:2004-06-23
IPC分类号: A61K38/17 , A61P19/00 , A61P29/00 , A61P31/04 , A61P31/12 , A61P35/00 , A61P37/00 , C07H21/04 , C07K14/715 , C12N1/19 , C12N1/21 , C12N15/63 , C12N5/10 , C12P21/00
CPC分类号: C07K14/7155 , A61K38/00 , A61K47/60 , C07K2319/00
摘要: A polypeptide-dimer comprising two soluble gp130 molecules is described, wherein at least one of said soluble gp130 molecules is covalently linked to polyethylene glycol. Furthermore, a pharmaceutical composition containing said dimer and various medical uses are described.
摘要翻译: 描述了包含两种可溶性gp130分子的多肽 - 二聚体,其中至少一种所述可溶性gp130分子与聚乙二醇共价连接。 此外,描述了含有所述二聚体和各种医疗用途的药物组合物。
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