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公开(公告)号:US5849550A
公开(公告)日:1998-12-15
申请号:US497397
申请日:1995-06-30
CPC分类号: C12P17/162
摘要: A method for producing lysocellin in bead form comprises: (a) cultivating a lysocellin-producing microorganism in an aqueous nutrient-containing fermentation broth under lysocellin-producing conditions; (b) adding a base or inorganic phosphate to the fermentation broth within about the first 24 hours of the beginning of the fermentation in an amount sufficient to ensure that the lysocellin is produced in the form of a cation salt of lysocellin; (c) providing a lipid to the fermentation broth such that the lipid is present in the broth in a sufficient amount to form discrete beads with the lysocellin in the fermentation broth; and (d) separating the beads from the broth.
摘要翻译: 用于制备珠粒形式的溶血细胞素的方法包括:(a)在产生溶血细胞素的条件下,在含水营养的发酵液中培养产生溶血细胞纤维素的微生物; (b)在发酵开始的最初24小时之内,将发酵液中的碱或无机磷酸盐以足以确保溶血细胞素的阳离子盐形式产生的量的量加入到发酵液中; (c)向发酵液提供脂质,使得脂肪以足够的量存在于肉汤中,以在发酵液中与溶菌酶一起形成离散的珠粒; 和(d)从培养液中分离珠子。
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公开(公告)号:US06919464B1
公开(公告)日:2005-07-19
申请号:US10471795
申请日:2002-03-21
申请人: Gary D. Crouse , Donald R. Hahn , Paul R. Graupner , Jeffrey R. Gilbert , Paul Lewer , Jesse L. Balcer
发明人: Gary D. Crouse , Donald R. Hahn , Paul R. Graupner , Jeffrey R. Gilbert , Paul Lewer , Jesse L. Balcer
IPC分类号: A01N45/02 , A01N63/04 , C07H15/26 , C07H17/08 , C07D313/06 , A61K31/365
摘要: Macrolide compounds produced by synthetic modification of factors produced by NRRL 30141 have insecticidal and acaricidal activity and are useful intermediates for preparing additional insecticidal and acaricidal compounds
摘要翻译: 通过NRRL 30141产生的因子的合成修饰产生的大环内酯类化合物具有杀虫和杀螨活性,是制备额外杀虫和杀螨化合物的有用中间体
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公开(公告)号:US06800614B2
公开(公告)日:2004-10-05
申请号:US10217533
申请日:2002-08-13
申请人: Paul Lewer , Donald R. Hahn , Laura L. Karr , Paul R. Graupner , Jeffrey R. Gilbert , Thomas V. Worden , Raymond C. Yao , Dennis W. Norton
发明人: Paul Lewer , Donald R. Hahn , Laura L. Karr , Paul R. Graupner , Jeffrey R. Gilbert , Thomas V. Worden , Raymond C. Yao , Dennis W. Norton
IPC分类号: A01N4322
摘要: Macrolide compounds produced by culturing Saccharopolyspora species LW107129 (NRRL 30141) have insecticidal and acaricidal activity and are useful intermediates for preparing spinosyn analogs.
摘要翻译: 通过培养多孢子虫种类LW107129(NRRL 30141)产生的大环内酯类化合物具有杀虫和杀螨活性,是制备多杀菌素类似物的有用中间体。
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公开(公告)号:US06455504B1
公开(公告)日:2002-09-24
申请号:US09661065
申请日:2000-09-13
申请人: Paul Lewer , Donald R. Hahn , Laura L. Karr , Paul R. Graupner , Jeffrey R. Gilbert , Thomas V. Worden , Raymond C. Yao , Dennis W. Norton
发明人: Paul Lewer , Donald R. Hahn , Laura L. Karr , Paul R. Graupner , Jeffrey R. Gilbert , Thomas V. Worden , Raymond C. Yao , Dennis W. Norton
IPC分类号: A01N4322
摘要: Macrolide compounds produced by culturing Saccharopolyspora species LW107129 (NRRL 30141) have insecticidal and acaricidal activity and are useful intermediates for preparing spinosyn analogs.
摘要翻译: 通过培养多孢子虫种类LW107129(NRRL 30141)产生的大环内酯类化合物具有杀虫和杀螨活性,是制备多杀菌素类似物的有用中间体。
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