公开(公告)号：US08008454B2

公开(公告)日：2011-08-30

申请号：US10433508

申请日：2001-12-10

申请人： Dong-Eok Lee ,  Myung-Suk Oh ,  Ki-Wan Kim ,  Bo-Sup Chung ,  Byung-Jhip Ha ,  Ji-Sook Park

发明人： Dong-Eok Lee ,  Myung-Suk Oh ,  Ki-Wan Kim ,  Bo-Sup Chung ,  Byung-Jhip Ha ,  Ji-Sook Park

IPC分类号： C07K1/00 ,  C07H21/04

CPC分类号： C07K14/505 ,  C07K14/59 ,  C07K2319/00

摘要： The present invention relates to a fusion protein in which a carboxy terminal of human erythropoietin (EPO) is fused with a carboxy terminal peptide fragment of β subunit of human chorionic gonadotropin (HCG), to DNA encoding the fusion protein, and to a method for preparation of the fusion protein. The fusion protein has the enhanced in vivo activity of erythropoietin.

摘要翻译： 本发明涉及融合蛋白，其中人促红细胞生成素（EPO）的羧基末端与羧基末端肽片段“ 人绒毛膜促性腺激素（HCG）的亚单位，编码融合蛋白的DNA，以及融合蛋白的制备方法。 融合蛋白具有增强的红细胞生成素的体内活性。

公开(公告)号：US20090221037A1

公开(公告)日：2009-09-03

申请号：US10433508

申请日：2001-12-10

申请人： Dong-Eok Lee ,  Myung-Suk Oh ,  Ki-Wan Kim ,  Bo-Sup Chung ,  Byung-Jhip Ha ,  Ji-Sook Park

发明人： Dong-Eok Lee ,  Myung-Suk Oh ,  Ki-Wan Kim ,  Bo-Sup Chung ,  Byung-Jhip Ha ,  Ji-Sook Park

IPC分类号： C12P21/06 ,  C07K14/505 ,  C07H21/04

CPC分类号： C07K14/505 ,  C07K14/59 ,  C07K2319/00

摘要： The present invention relates to a fusion protein in which a carboxy terminal of human erythropoietin (EPO) is fused with a carboxy terminal peptide fragment of β subunit of human chorionic gonadotropin (HCG), to DNA encoding the fusion protein, and to a method for preparation of the fusion protein. The fusion protein has the enhanced in vivo activity of erythropoietin.

摘要翻译： 本发明涉及将人促红细胞生成素（EPO）的羧基末端与人绒毛膜促性腺激素（HCG）的β亚基的羧基末端肽片段与编码融合蛋白质的DNA融合的融合蛋白质， 融合蛋白的制备。 融合蛋白具有增强的红细胞生成素的体内活性。

公开(公告)号：US07098318B2

公开(公告)日：2006-08-29

申请号：US10230454

申请日：2002-08-29

申请人： Dong-Eok Lee ,  Myung-Suk Oh ,  Bo-Sup Chung ,  Ji-Sook Park ,  Ki-Wan Kim

发明人： Dong-Eok Lee ,  Myung-Suk Oh ,  Bo-Sup Chung ,  Ji-Sook Park ,  Ki-Wan Kim

IPC分类号： C07K14/59 ,  C07H21/00 ,  C12P21/06 ,  A61K38/24

CPC分类号： C07K14/524 ,  A61K38/00 ,  C07K14/505 ,  C07K2319/00

摘要： The present invention relates to a fusion protein having enhanced in vivo activity of erythropoietin wherein a carboxy terminal peptide fragment of thrombopoietin is fused with the carboxy terminal of human erythropoietin. This fusion protein has highly enhanced in vivo half-life due to increased carbohydrate content without loss of the inherent activity of erythropoietin, and does not cause any antigenicity when applied to the human body.

公开(公告)号：US20120229813A1

公开(公告)日：2012-09-13

申请号：US13501049

申请日：2010-10-14

申请人： Ki-Wan Kim ,  Man-Sik Jeon ,  Un-Sang Jung ,  Chang-Ho Lee

发明人： Ki-Wan Kim ,  Man-Sik Jeon ,  Un-Sang Jung ,  Chang-Ho Lee

IPC分类号： G01B9/02 ,  G01J3/51

CPC分类号： A61B5/6852 ,  A61B5/0066 ,  G01B9/02044 ,  G01B9/02091 ,  G01J3/0208 ,  G01J3/12 ,  G01J3/18

摘要： In a wavelength detector and an OCT including the same, the wavelength detector includes a wavelength filter by which at least one of the diffraction beams of a coherent input light is selected as a selection beam having a desired frequency by using a flat plate and at least a slit penetrating through the flat plate. The pixel having image data of an OCT image is mapped to the frequency of the selection beam by one to one, thereby improving uniformity of the resolution of the OCT image along a depth of the inspection object. The frequency of the selection beam is determined by an optical spectrum analyzer before initiating the OCT inspection to the object.

摘要翻译： 在波长检测器和包括其的OCT中，波长检测器包括波长滤波器，通过该波长滤波器，通过使用平板将至少一个相干输入光的衍射光束选择为具有期望频率的选择光束，并且至少 穿过平板的狭缝。 具有OCT图像的图像数据的像素被映射到选择光束的频率一对一，从而提高沿着检查对象的深度的OCT图像的分辨率的均匀性。 在对物体进行OCT检查之前，选择光束的频率由光谱分析仪确定。

公开(公告)号：US08259083B2

公开(公告)日：2012-09-04

申请号：US12503314

申请日：2009-07-15

申请人： Ki-Wan Kim

发明人： Ki-Wan Kim

IPC分类号： G09G5/00

CPC分类号： G06F1/1626 ,  G06F1/169 ,  G06F3/041 ,  G06F3/0488

摘要： The present invention relates to a mobile device having a backpanel touchpad, and more particularly, to a technique for enabling cursor movements and execution instructions on a frontpanel display screen to be inputted through a touchpad positioned at a backpanel of a mobile device. Accordingly, a touchpad is disposed on a back side of a mobile device, so that the mobile device can be controlled through a contact point at which a user's finger is naturally positioned when a user holds the mobile device with a user's hand. Further, a backpanel touchpad is operated, so that a display screen is not covered with the user's finger.

摘要翻译： 本发明涉及一种具有背板触摸板的移动设备，更具体地说，涉及通过位于移动设备的背板上的触摸板来输入前面板显示屏幕上的光标移动和执行指令的技术。 因此，触摸板设置在移动设备的背面，使得当用户用用户的手握住移动设备时，可以通过用户手指自然定位的接触点来控制移动设备。 此外，操作背板触摸板，使得显示屏幕不被用户的手指覆盖。