公开(公告)号：US20050159783A1

公开(公告)日：2005-07-21

申请号：US10760155

申请日：2004-01-16

申请人： Douglas Hettrick ,  David Euler ,  Eduardo Warman ,  Michael Ujhelyi ,  Rahul Mehra ,  Paul Ziegler ,  Shailesh Kumar Musley ,  Charles Distad ,  David Ritscher

发明人： Douglas Hettrick ,  David Euler ,  Eduardo Warman ,  Michael Ujhelyi ,  Rahul Mehra ,  Paul Ziegler ,  Shailesh Kumar Musley ,  Charles Distad ,  David Ritscher

IPC分类号： A61N1/362 ,  A61N1/365 ,  A61N1/37 ,  A61N1/39

CPC分类号： A61N1/3702 ,  A61N1/3621 ,  A61N1/365 ,  A61N1/36564 ,  A61N1/395 ,  A61N1/3962

摘要： Control of defibrillation therapy delivered by implantable medical devices (IMDS) using hemodynamic sensor feedback is disclosed. The hemodynamic sensor feedback allows for increased control over application of atrial defibrillation therapy. Specifically, the therapy is delivered when a fibrillation episode results in a discrete loss of hemodynamic function. Defibrillation therapy is thus withheld for hemodynamically benign arrhythmias.

摘要翻译： 公开了使用血液动力学传感器反馈控制由可植入医疗装置（IMDS）递送的除颤疗法。 血液动力学传感器反馈允许增加对心房除颤治疗的应用的控制。 具体来说，当纤维性颤动发作导致血液动力学功能的离散损失时，进行治疗。 因此，对于血液动力学良性心律失常，禁止使用除颤疗法。

公开(公告)号：US06876880B2

公开(公告)日：2005-04-05

申请号：US10034060

申请日：2001-12-20

申请人： Michael F. Hess ,  Rahul Mehra ,  Eduardo N. Warman ,  Nirav V. Sheth ,  Mark L. Brown ,  David Ritscher

发明人： Michael F. Hess ,  Rahul Mehra ,  Eduardo N. Warman ,  Nirav V. Sheth ,  Mark L. Brown ,  David Ritscher

IPC分类号： A61N1/365 ,  A61N1/362 ,  A61N1/39

CPC分类号： A61N1/3622 ,  A61N1/3624

摘要： The invention relates to the use of atrial pacing therapies to treat atrial tachycardia (AT). When an AT episode is detected, an implantable medical device applies an ATP therapy. If the AT episode persists, the ATP therapy may be automatically reapplied at a later time during the course of the same AT episode. In particular, previously used ATP therapies are reapplied when episodic conditions, such as cycle length or cycle regularity, change. Although a particular ATP therapy initially may be unsuccessful in terminating the AT, it may prove successful when the cycle length or regularity of the atrial rhythm changes. As the rhythm slows down, the AT may be more responsive to ATP therapies that were previously unsuccessful. As a result, potentially efficacious ATP therapies can be reapplied to terminate AT episodes, and reduce the number of episodes that require more aggressive termination by painful, atrial shocks.

摘要翻译： 本发明涉及心房起搏疗法用于治疗房性心动过速（AT）的用途。 当检测到AT发作时，可植入医疗装置应用ATP疗法。 如果AT发作持续存在，ATP疗法可能会在相同的AT发作过程中的较晚时间自动重新应用。 特别是，当诸如循环长度或循环规律性等情况时，先前使用的ATP疗法将被重新应用。 尽管特定的ATP疗法最初可能不能终止AT，但是当心房节律的周期长度或规律性发生变化时，可能会成功。 随着节奏减慢，AT可能对以前不成功的ATP疗法更有反应。 因此，可以重新应用潜在有效的ATP疗法来终止AT发作，并通过痛苦的心房休克减少需要更积极终止的发作次数。

公开(公告)号：US20060247548A1

公开(公告)日：2006-11-02

申请号：US11321541

申请日：2005-12-29

申请人： Shantanu Sarkar ,  David Ritscher

发明人： Shantanu Sarkar ,  David Ritscher

IPC分类号： A61B5/04

CPC分类号： A61B5/0464 ,  A61B5/046

摘要： A multi-layer method for detecting atrial arrhythmias using ventricular cycle length information that includes performing a base layer algorithm for detecting the onset and offset of an atrial tachyarrhythmia. The multi-layer method further includes one or more higher layer algorithms executed in response to a base layer detection to confirm or reject the base layer detection. The base layer is designed to operate with high sensitivity to atrial fibrillation and/or organized atrial tachycardia and the higher layer is designed to operate with high sensitivity and high specificity to atrial fibrillation and/or organized atrial tachycardia.

公开(公告)号：US20060247547A1

公开(公告)日：2006-11-02

申请号：US11321183

申请日：2005-12-29

申请人： Shantanu Sarkar ,  David Ritscher

发明人： Shantanu Sarkar ,  David Ritscher

IPC分类号： A61B5/04

CPC分类号： A61B5/0464

摘要： A method and apparatus for detecting atrial arrhythmias and discriminating atrial fibrillation (AF) and organized atrial tachycardia (OAT) that includes defining a threshold detection criteria for a cluster signature evidence metric corresponding to a Lorenz distribution of ventricular cycle lengths representative of AF or OAT. Using a signal containing VCL information, a number of consecutive ventricular cycle lengths are determined during a selected time interval for generating a one-dimensional or a two-dimensional histogram as a numerical representation of a Lorenz plot of VCLs. A number of cluster signature metrics are computed using the stored ventricular cycle length information, and a cluster signature evidence metric is computed from the cluster signature metrics. AF or OAT is detected if a comparative analysis of a corresponding cluster signature evidence metric meets a respective threshold detection criteria.