公开(公告)号：US11123465B2

公开(公告)日：2021-09-21

申请号：US16303687

申请日：2017-05-26

Applicant: DREXEL UNIVERSITY

Inventor： Yury Gogotsi ,  Vadym Mochalin ,  Nicholas Pescatore

IPC: A61M1/34 ,  B01J20/20 ,  B01J20/28 ,  B01J20/32

Abstract: The present disclosure is directed to methods of removing proteins, including cytokines, from blood and blood products, the methods comprising contacting the blood or blood product with a form of carbon having high graphitic contents and slit-shaped mesopores and macropores, the pore size dimensions chosen to be comparable to the size of the proteins, wherein the contacting results in the removal of high levels of the protein from the blood or blood product in minutes or hours.

公开(公告)号：US20210379263A1

公开(公告)日：2021-12-09

申请号：US17402856

申请日：2021-08-16

Applicant: Drexel University

Inventor： Yury Gogotsi ,  Vadym Mochalin ,  Nicholas Pescatore

IPC: A61M1/34 ,  B01J20/20 ,  B01J20/28 ,  B01J20/32

Abstract: The present disclosure is directed to methods of removing proteins, including cytokines, from blood and blood products, the methods comprising contacting the blood or blood product with a form of carbon having high graphitic contents and slit-shaped mesopores and macropores, the pore size dimensions chosen to be comparable to the size of the proteins, wherein the contacting results in the removal of high levels of the protein from the blood or blood product in minutes or hours.

公开(公告)号：US11918723B2

公开(公告)日：2024-03-05

申请号：US17402856

申请日：2021-08-16

Applicant: Drexel University

Inventor： Yury Gogotsi ,  Vadym Mochalin ,  Nicholas Pescatore

IPC: A61M1/34 ,  B01J20/20 ,  B01J20/28 ,  B01J20/32

CPC classification number: A61M1/3486 ,  B01J20/205 ,  B01J20/28083 ,  B01J20/28085 ,  B01J20/321 ,  A61M2202/0445 ,  A61M2202/07

Abstract: The present disclosure is directed to methods of removing proteins, including cytokines, from blood and blood products, the methods comprising contacting the blood or blood product with a form of carbon having high graphitic contents and slit-shaped mesopores and macropores, the pore size dimensions chosen to be comparable to the size of the proteins, wherein the contacting results in the removal of high levels of the protein from the blood or blood product in minutes or hours.