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公开(公告)号:US11071783B2
公开(公告)日:2021-07-27
申请号:US15559314
申请日:2016-03-21
发明人: Barton F. Haynes , Hua-Xin Liao , M. Anthony Moody , LaTonya Williams , Kevin J. Wiehe , Gilad Adi Ofek
摘要: The invention is directed to HIV-1 neutralizing antibodies and methods for their uses.
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公开(公告)号:US11161895B2
公开(公告)日:2021-11-02
申请号:US16337264
申请日:2017-10-03
申请人: Duke University
IPC分类号: C07K16/10 , A61K39/00 , A61K39/12 , A61K39/395 , C07K16/00 , A61K39/21 , C12N7/00 , G01N33/569
摘要: The invention is directed to methods to identify improbable mutations in the heavy or light chain variable domain of an antibody, methods to identify antigens which bind to antibodies comprising such improbable mutations, and methods of using such antigens to induce immune responses.
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