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公开(公告)号：US20180273532A1
公开(公告)日：2018-09-27
申请号：US15841767
申请日：2017-12-14
Applicant: EISAI R&D MANAGEMENT CO., LTD.
Inventor： Roch Boivin , Eric Carlson , Atsushi Endo , Hans Hansen , Lynn D. Hawkins , Sally Ishizaka , Matthew Mackey , Sridhar Narayan , Takashi Satoh , Shawn Schiller
IPC: C07D471/04 , A61K31/55 , C07D487/04 , A61K31/519
CPC classification number: C07D471/04 , A61K31/519 , A61K31/55 , C07D487/04 , Y02P20/582
Abstract: Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.
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公开(公告)号：US09850242B2
公开(公告)日：2017-12-26
申请号：US15233520
申请日：2016-08-10
Applicant: EISAI R&D MANAGEMENT CO., LTD.
Inventor： Roch Boivin , Eric Carlson , Atsushi Endo , Hans Hansen , Lynn D. Hawkins , Sally Ishizaka , Matthew Mackey , Sridhar Narayan , Takashi Satoh , Shawn Schiller
IPC: A01N43/90 , A61K31/519 , C07D471/04 , C07D487/04 , A61K31/55
CPC classification number: C07D471/04 , A61K31/519 , A61K31/55 , C07D487/04 , Y02P20/582
Abstract: Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.
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Patent Agency Ranking
公开(公告)号：US20160339032A1
公开(公告)日：2016-11-24
申请号：US15233520
申请日：2016-08-10
Applicant: EISAI R&D MANAGEMENT CO., LTD.
Inventor： Roch Boivin , Eric Carlson , Atsushi Endo , Hans Hansen , Lynn D. Hawkins , Sally Ishizaka , Matthew Mackey , Sridhar Narayan , Takashi Satoh , Shawn Schiller
IPC: A61K31/519 , A61K31/55
CPC classification number: C07D471/04 , A61K31/519 , A61K31/55 , C07D487/04 , Y02P20/582
Abstract: Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis
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公开(公告)号：US09446046B2
公开(公告)日：2016-09-20
申请号：US14806174
申请日：2015-07-22
Applicant: EISAI R&D MANAGEMENT CO., LTD.
Inventor： Roch Boivin , Eric Carlson , Atsushi Endo , Hans Hansen , Lynn D. Hawkins , Sally Ishizaka , Matthew Mackey , Sridhar Narayan , Takashi Satoh , Shawn Schiller
IPC: A01N43/90 , A61K31/519 , C07D471/04 , C07D487/04
CPC classification number: C07D471/04 , A61K31/519 , A61K31/55 , C07D487/04 , Y02P20/582
Abstract: Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.
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公开(公告)号：US11130758B2
公开(公告)日：2021-09-28
申请号：US16845594
申请日：2020-04-10
Applicant: Eisai R&D Management Co., Ltd.
Inventor： Roch Boivin , Eric Carlson , Atsushi Endo , Hans Hansen , Lynn D. Hawkins , Sally Ishizaka , Matthew Mackey , Sridhar Narayan , Takashi Satoh , Shawn Schiller
IPC: C07D487/04 , C07D471/04 , A61K31/519 , A61K31/55
Abstract: Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.
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公开(公告)号：US09663486B2
公开(公告)日：2017-05-30
申请号：US14908164
申请日：2014-10-14
Applicant: EISAI R&D MANAGEMENT CO., LTD.
Inventor： Roch Boivin , Hans Hansen , Sally Ishizaka , Matthew Mackey , Shawn Schiller , Chikako Ogawa , Sridhar Narayan , Peter Bertinato , Gregory Berger , Atsushi Endo , Robert T. Yu , Lynn Hawkins
IPC: C07D401/02 , C07D413/14 , C07D471/04 , C07D401/14 , C07D417/14 , C07D401/04
CPC classification number: C07D401/02 , C07D401/04 , C07D401/14 , C07D413/14 , C07D417/14 , C07D471/04
Abstract: Embodiments of the disclosure relate to selectively substituted quinoline compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.
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公开(公告)号：US20160030430A1
公开(公告)日：2016-02-04
申请号：US14806174
申请日：2015-07-22
Applicant: EISAI R&D MANAGEMENT CO., LTD.
Inventor： Roch Boivin , Eric Carlson , Atsushi Endo , Hans Hansen , Lynn D. Hawkins , Sally Ishizaka , Matthew Mackey , Sridhar Narayan , Takashi Satoh , Shawn Schiller
IPC: A61K31/519
CPC classification number: C07D471/04 , A61K31/519 , A61K31/55 , C07D487/04 , Y02P20/582
Abstract: Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis
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