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公开(公告)号：US20240100165A1
公开(公告)日：2024-03-28
申请号：US18548680
申请日：2022-02-24
CPC分类号： A61K47/32 , A61K9/0053 , A61K9/1075
摘要： A method of preparing a specific solid self-nanoemulsifying drug delivery system involves applying an obtained self-nanoemulsifying drug delivery system on a mixture. The mixture contains (ia) 60 to 90 parts by weight of at least one dimethylaminoethyl methacrylate-butyl methacrylate-methyl methacrylate copolymer; (iia) 10 to 40 parts by weight of at least one methacrylic acid-ethyl acrylate copolymer; and (iiia) optionally, at least one additive; where the sum of (a) and (iia) is 100 parts by weight. The solid self-nanoemulsifying drug delivery system obtained by the method of the present invention is useful as a medicament.
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公开(公告)号：US20230218525A1
公开(公告)日：2023-07-13
申请号：US17999920
申请日：2021-05-26
IPC分类号： A61K9/107 , A61K47/32 , A61K31/635 , A61K31/216 , A61K31/536
CPC分类号： A61K9/1075 , A61K47/32 , A61K31/635 , A61K31/216 , A61K31/536
摘要： A pharmaceutical composition contains at least one methacrylic copolymer having units derived from methacrylamide; at least one pharmaceutically active ingredient; at least one lipid component; and at least one surfactant. The pharmaceutical composition can be used as a medicament. A method can be used to prepare a solid self-nanoemulsifying drug delivery system using the different compounds of the pharmaceutical composition.
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公开(公告)号：US20230203223A1
公开(公告)日：2023-06-29
申请号：US17999916
申请日：2021-05-26
发明人： Thomas Endres , Christian Moers , Fabian-Pascal Schmied , Jan Hendrik Schattka , Kathrin Nollenberger
IPC分类号： C08F220/60 , A61K31/216 , A61K9/28 , A61K31/522 , A23L33/10
CPC分类号： C08F220/60 , A61K31/216 , A61K9/2846 , A61K31/522 , A23L33/10
摘要： A novel methacrylic copolymer contains units derived from at least one alkyl methacrylate and methacrylamide. The units derived from methacrylamide are present in at least 34 wt.-%, based on the total weight of the methacrylic copolymer. A method can be used for preparing these novel methacylic copolymers. Pharmaceutical compositions, nutraceutical compositions, coated pharmaceutical or nutraceutical dosage forms, as well as nano- or microparticles can contain the methacrylic copolymer. The methacrylic copolymer can be used as a coating, as a carrier, and as a matrix for an amorphous solid dispersion.
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公开(公告)号：US11958981B2
公开(公告)日：2024-04-16
申请号：US17260345
申请日：2019-07-09
IPC分类号： C09C1/30 , B01J2/30 , C04B26/06 , C04B26/32 , C04B40/02 , C04B111/27 , C04B111/28 , E04B1/74 , F16L59/02
CPC分类号： C09C1/309 , B01J2/30 , C04B26/06 , C04B26/32 , C04B40/0263 , F16L59/028 , C01P2004/50 , C01P2004/61 , C01P2004/80 , C01P2006/11 , C01P2006/12 , C01P2006/90 , C04B2111/27 , C04B2111/28 , C04B2201/20 , E04B2001/742 , C04B26/285 , C04B14/066 , C04B2103/0014 , C04B2103/0019 , C04B2103/0021 , C04B2103/56
摘要： Hydrophobized granular material comprising from 30 to 95% by weight of a pyrogenic mixed oxide based on silica and at least one oxide of metal M selected from of Al, Ti and Fe with the content of metal M oxide in the mixed oxide being from 01 to 10% by weight, and from 5 to 70% by weight of at least one IR-opacifier selected from the group consisting of silicon carbide, zirconium dioxide, ilmenites, iron titanates, zirconium silicates, manganese oxides, graphites, carbon blacks and mixtures thereof.
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公开(公告)号：US11565974B2
公开(公告)日：2023-01-31
申请号：US16478169
申请日：2018-01-18
IPC分类号： C04B35/14 , C04B35/626 , C04B35/64 , C04B41/00 , C04B41/45 , C04B41/49 , C04B41/84 , F16L59/02
摘要： The present invention relates to a granular thermal insulation material comprising hydrophobized silicon dioxide and at least one IR opacifier, having a tamped density of up to 250 g/l and a compressive strength according to DIN EN 826:2013 at 50% compression of 150 to 300 kPa or greater than 300 kPa, to processes for production thereof and to the use thereof for thermal insulation.
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