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公开(公告)号:US09499627B2
公开(公告)日:2016-11-22
申请号:US13388722
申请日:2010-08-03
IPC分类号: C07K14/52 , C07K14/525 , C07K16/28 , A61K38/19 , A61K39/395 , C07K14/705 , C07K14/715 , A61K38/17 , A61K39/00
CPC分类号: C07K16/2878 , A61K38/17 , A61K38/19 , A61K38/191 , A61K39/3955 , A61K2039/505 , C07K14/525 , C07K14/705 , C07K14/7151 , C07K16/28 , C07K16/2863 , C07K2317/75
摘要: Compositions specific for TNF-receptor superfamily member 25 (TNFRSF25, DR3) modulate the immune response by regulating T regulatory cells.
摘要翻译: 针对TNF受体超家族成员25(TNFRSF25,DR3)特异性的组合物通过调节T调节细胞调节免疫应答。
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公开(公告)号:US20120135011A1
公开(公告)日:2012-05-31
申请号:US13388722
申请日:2010-08-03
IPC分类号: A61K39/395 , C07K14/00 , C07K16/18 , C07H21/00 , A61P29/00 , A61P31/00 , A61P11/06 , A61P1/00 , A61P19/02 , A61P37/04 , A61P37/06 , A61P37/02 , A61P37/08 , A61P35/00 , A61P41/00 , A61K39/00
CPC分类号: C07K16/2878 , A61K38/17 , A61K38/19 , A61K38/191 , A61K39/3955 , A61K2039/505 , C07K14/525 , C07K14/705 , C07K14/7151 , C07K16/28 , C07K16/2863 , C07K2317/75
摘要: Compositions specific for TNF-receptor superfamily member 25 (TNFRSF25, DR3) modulate the immune response by regulating T regulatory cells.
摘要翻译: 针对TNF受体超家族成员25(TNFRSF25,DR3)特异性的组合物通过调节T调节细胞调节免疫应答。
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公开(公告)号:US20120029472A1
公开(公告)日:2012-02-02
申请号:US13140698
申请日:2009-12-21
申请人: Eckhard R. Podack , Natasa Strbo , Vadim Deyev , Taylor Schreiber
发明人: Eckhard R. Podack , Natasa Strbo , Vadim Deyev , Taylor Schreiber
CPC分类号: C07K16/2878 , A61K39/39 , A61K2039/505 , C07K2317/74
摘要: TNFR25 compositions enhance the immune response against antigens. Administration of TNFR25 agonists was found to enhance tumor rejection, responses against viral diseases and other infectious organisms.
摘要翻译: TNFR25组合物增强针对抗原的免疫应答。 发现TNFR25激动剂的施用可以增强肿瘤排斥反应,反应病毒性疾病和其他感染性生物。
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