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1.发明授权2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses 有权2-氧代-1-吡咯烷衍生物，其制备方法及其用途公开(公告)号：US08034958B2
公开(公告)日：2011-10-11
申请号：US12656808
申请日：2010-02-17
申请人： Edmond Differding , Benoît Kenda , Bénédicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
发明人： Edmond Differding , Benoît Kenda , Bénédicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
IPC分类号： C07D207/00
CPC分类号： C07D207/26 , A61K31/4015 , C07C237/12 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/12 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04
摘要： The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
摘要翻译： 本发明涉及式I的2-氧代-1-吡咯烷衍生物，其中取代基如说明书中所定义，以及它们作为药物的用途。 本发明的化合物特别适用于治疗诸如癫痫的神经障碍。
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2.发明授权2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses 有权2-氧代-1-吡咯烷衍生物，其制备方法及其用途公开(公告)号：US07358276B2
公开(公告)日：2008-04-15
申请号：US11043176
申请日：2005-01-27
申请人： Edmond Differding , Benoît Kenda , Bénédicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
发明人： Edmond Differding , Benoît Kenda , Bénédicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
IPC分类号： C07C205/00 , A61K31/21
CPC分类号： C07D207/26 , A61K31/4015 , C07C237/12 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/12 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04
摘要： The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
摘要翻译： 本发明涉及式I的2-氧代-1-吡咯烷衍生物，其中取代基如说明书中所定义，以及它们作为药物的用途。 本发明的化合物特别适用于治疗诸如癫痫的神经障碍。
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3.发明授权2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses 有权2-氧代-1-吡咯烷衍生物，其制备方法及其用途公开(公告)号：US06911461B2
公开(公告)日：2005-06-28
申请号：US10693917
申请日：2003-10-28
申请人： Edmond Differding , Benoît Kenda , Bénédicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
发明人： Edmond Differding , Benoît Kenda , Bénédicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
IPC分类号： C07D401/04 , A61K31/4015 , A61K31/4025 , A61K31/41 , A61K31/4178 , A61K31/4188 , A61K31/4192 , A61K31/4196 , A61K31/422 , A61K31/4245 , A61K31/427 , A61K31/433 , A61K31/4439 , A61K31/497 , A61K31/506 , A61K31/541 , A61P9/00 , A61P9/06 , A61P9/10 , A61P11/00 , A61P11/06 , A61P21/00 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/16 , A61P37/08 , C07B61/00 , C07C237/06 , C07C237/12 , C07D207/26 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/06 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04 , A61K31/426 , C07D277/20
CPC分类号： C07D207/26 , A61K31/4015 , C07C237/12 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/12 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04
摘要： The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
摘要翻译： 本发明涉及式I的2-氧代-1-吡咯烷衍生物，其中取代基如说明书中所定义，以及它们作为药物的用途。 本发明的化合物特别适用于治疗诸如癫痫的神经障碍。
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4.发明申请2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses 有权2-氧代-1-吡咯烷衍生物，其制备方法及其用途公开(公告)号：US20100222576A1
公开(公告)日：2010-09-02
申请号：US12656808
申请日：2010-02-17
申请人： Edmond Differding , Benoît Kenda , Bénédicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
发明人： Edmond Differding , Benoît Kenda , Bénédicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
IPC分类号： C07D417/06 , C07D207/267 , C07D403/06 , C07D403/04
CPC分类号： C07D207/26 , A61K31/4015 , C07C237/12 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/12 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04
摘要： The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals.The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
摘要翻译： 本发明涉及式I的2-氧代-1-吡咯烷衍生物，其中取代基如说明书中所定义，以及它们作为药物的用途。 本发明的化合物特别适用于治疗诸如癫痫的神经障碍。
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5.发明授权2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses 有权2-氧代-1-吡咯烷衍生物，其制备方法及其用途公开(公告)号：US07692028B2
公开(公告)日：2010-04-06
申请号：US12000512
申请日：2007-12-13
申请人： Edmond Differding , Benoît Kenda , Bénédicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
发明人： Edmond Differding , Benoît Kenda , Bénédicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
IPC分类号： C07D207/00
CPC分类号： C07D207/26 , A61K31/4015 , C07C237/12 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/12 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04
摘要： The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
摘要翻译： 本发明涉及式I的2-氧代-1-吡咯烷衍生物，其中取代基如说明书中所定义，以及它们作为药物的用途。 本发明的化合物特别适用于治疗诸如癫痫的神经障碍。
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6.发明授权2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses 有权2-氧代-1-吡咯烷衍生物，其制备方法及其用途公开(公告)号：US06806287B2
公开(公告)日：2004-10-19
申请号：US10694090
申请日：2003-10-28
申请人： Edmond Differding , Benoît Kenda , Bénédicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
发明人： Edmond Differding , Benoît Kenda , Bénédicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
IPC分类号： A61K314015
CPC分类号： C07D207/26 , A61K31/4015 , C07C237/12 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/12 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04
摘要： The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
摘要翻译： 本发明涉及式I的2-氧代-1-吡咯烷衍生物，其中取代基如说明书中所定义，以及它们作为药物的用途。本发明的化合物特别适用于治疗诸如癫痫的神经障碍。
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7.发明授权2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses 有权2-氧代-1-吡咯烷衍生物，其制备方法及其用途公开(公告)号：US06784197B2
公开(公告)日：2004-08-31
申请号：US10204266
申请日：2002-08-20
申请人： Edmond Differding , Benoît Kenda , Bénédicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
发明人： Edmond Differding , Benoît Kenda , Bénédicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
IPC分类号： A61K31426
CPC分类号： C07D207/26 , A61K31/4015 , C07C237/12 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/12 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04
摘要： The invention concerns 2-oxo-1-pyrrolidine derivatives of formula (I) wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
摘要翻译： 本发明涉及式（I）的2-氧代-1-吡咯烷衍生物，其中取代基如说明书中所定义，以及它们作为药物的用途。 本发明的化合物特别适用于治疗诸如癫痫的神经障碍。
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8.发明申请2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses 审中-公开2-氧代-1-吡咯烷衍生物，其制备方法及其用途公开(公告)号：US20050171187A1
公开(公告)日：2005-08-04
申请号：US11043145
申请日：2005-01-27
申请人： Edmond Differding , Benoit Kenda , Benedicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
发明人： Edmond Differding , Benoit Kenda , Benedicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
IPC分类号： C07D401/04 , A61K31/4015 , A61K31/4025 , A61K31/41 , A61K31/4178 , A61K31/4188 , A61K31/4192 , A61K31/4196 , A61K31/422 , A61K31/4245 , A61K31/427 , A61K31/433 , A61K31/4439 , A61K31/497 , A61K31/506 , A61K31/541 , A61P9/00 , A61P9/06 , A61P9/10 , A61P11/00 , A61P11/06 , A61P21/00 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/16 , A61P37/08 , C07B61/00 , C07C237/06 , C07C237/12 , C07D207/26 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/06 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04 , C07D207/12
CPC分类号： C07D207/26 , A61K31/4015 , C07C237/12 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/12 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04
摘要： The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
摘要翻译： 本发明涉及式I的2-氧代-1-吡咯烷衍生物，其中取代基如说明书中所定义，以及它们作为药物的用途。 本发明的化合物特别适用于治疗诸如癫痫的神经障碍。
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公开(公告)号：US20050171188A1
公开(公告)日：2005-08-04
申请号：US11043176
申请日：2005-01-27
申请人： Edmond Differding , Benoit Kenda , Benedicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
发明人： Edmond Differding , Benoit Kenda , Benedicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
IPC分类号： C07D401/04 , A61K31/4015 , A61K31/4025 , A61K31/41 , A61K31/4178 , A61K31/4188 , A61K31/4192 , A61K31/4196 , A61K31/422 , A61K31/4245 , A61K31/427 , A61K31/433 , A61K31/4439 , A61K31/497 , A61K31/506 , A61K31/541 , A61P9/00 , A61P9/06 , A61P9/10 , A61P11/00 , A61P11/06 , A61P21/00 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/16 , A61P37/08 , C07B61/00 , C07C237/06 , C07C237/12 , C07D207/26 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/06 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04 , C07D207/12
CPC分类号： C07D207/26 , A61K31/4015 , C07C237/12 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/12 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04
摘要： The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
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10.发明申请2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses 有权2-氧代-1-吡咯烷衍生物，其制备方法及其用途公开(公告)号：US20080097109A1
公开(公告)日：2008-04-24
申请号：US12000512
申请日：2007-12-13
申请人： Edmon Differding , Benoit Kenda , Benedicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrick Talaga
发明人： Edmon Differding , Benoit Kenda , Benedicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrick Talaga
IPC分类号： C07D207/12
CPC分类号： C07D207/26 , A61K31/4015 , C07C237/12 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/12 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04
摘要： The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
摘要翻译： 本发明涉及式I的2-氧代-1-吡咯烷衍生物，其中取代基如说明书中所定义，以及它们作为药物的用途。 本发明的化合物特别适用于治疗诸如癫痫的神经障碍。
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