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1.2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses 审中-公开
标题翻译: 2-氧代-1-吡咯烷衍生物,其制备方法及其用途公开(公告)号:US20050171187A1
公开(公告)日:2005-08-04
申请号:US11043145
申请日:2005-01-27
申请人: Edmond Differding , Benoit Kenda , Benedicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
发明人: Edmond Differding , Benoit Kenda , Benedicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
IPC分类号: C07D401/04 , A61K31/4015 , A61K31/4025 , A61K31/41 , A61K31/4178 , A61K31/4188 , A61K31/4192 , A61K31/4196 , A61K31/422 , A61K31/4245 , A61K31/427 , A61K31/433 , A61K31/4439 , A61K31/497 , A61K31/506 , A61K31/541 , A61P9/00 , A61P9/06 , A61P9/10 , A61P11/00 , A61P11/06 , A61P21/00 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/16 , A61P37/08 , C07B61/00 , C07C237/06 , C07C237/12 , C07D207/26 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/06 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04 , C07D207/12
CPC分类号: C07D207/26 , A61K31/4015 , C07C237/12 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/12 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04
摘要: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
摘要翻译: 本发明涉及式I的2-氧代-1-吡咯烷衍生物,其中取代基如说明书中所定义,以及它们作为药物的用途。 本发明的化合物特别适用于治疗诸如癫痫的神经障碍。
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公开(公告)号:US20050171188A1
公开(公告)日:2005-08-04
申请号:US11043176
申请日:2005-01-27
申请人: Edmond Differding , Benoit Kenda , Benedicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
发明人: Edmond Differding , Benoit Kenda , Benedicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrice Talaga
IPC分类号: C07D401/04 , A61K31/4015 , A61K31/4025 , A61K31/41 , A61K31/4178 , A61K31/4188 , A61K31/4192 , A61K31/4196 , A61K31/422 , A61K31/4245 , A61K31/427 , A61K31/433 , A61K31/4439 , A61K31/497 , A61K31/506 , A61K31/541 , A61P9/00 , A61P9/06 , A61P9/10 , A61P11/00 , A61P11/06 , A61P21/00 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/16 , A61P37/08 , C07B61/00 , C07C237/06 , C07C237/12 , C07D207/26 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/06 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04 , C07D207/12
CPC分类号: C07D207/26 , A61K31/4015 , C07C237/12 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/12 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04
摘要: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
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3.2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses 有权
标题翻译: 2-氧代-1-吡咯烷衍生物,其制备方法及其用途公开(公告)号:US20080097109A1
公开(公告)日:2008-04-24
申请号:US12000512
申请日:2007-12-13
申请人: Edmon Differding , Benoit Kenda , Benedicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrick Talaga
发明人: Edmon Differding , Benoit Kenda , Benedicte Lallemand , Alain Matagne , Philippe Michel , Patrick Pasau , Patrick Talaga
IPC分类号: C07D207/12
CPC分类号: C07D207/26 , A61K31/4015 , C07C237/12 , C07D207/27 , C07D207/273 , C07D207/277 , C07D307/33 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/12 , C07D409/04 , C07D413/04 , C07D417/04 , C07D495/04
摘要: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
摘要翻译: 本发明涉及式I的2-氧代-1-吡咯烷衍生物,其中取代基如说明书中所定义,以及它们作为药物的用途。 本发明的化合物特别适用于治疗诸如癫痫的神经障碍。
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4.2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses 有权
标题翻译: 2-氧代-1-吡咯烷衍生物,其制备方法及其用途公开(公告)号:US08586623B2
公开(公告)日:2013-11-19
申请号:US13441410
申请日:2012-04-06
申请人: Benoit Kenda , Yannick Quesnel , Ali Ates , Philippe Michel , Laurent Turet , Joel Mercier
发明人: Benoit Kenda , Yannick Quesnel , Ali Ates , Philippe Michel , Laurent Turet , Joel Mercier
IPC分类号: A01N43/36 , A61K31/40 , C07D409/00 , C07D411/00
CPC分类号: C07D513/04 , C07D401/06 , C07D403/06 , C07D413/06 , C07D417/06 , C07D471/04 , C07D473/00 , C07D487/04
摘要: The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
摘要翻译: 本发明涉及2-氧代-1-吡咯烷衍生物,其制备方法,含有它们的药物组合物及其作为药物的用途。
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公开(公告)号:US08518943B2
公开(公告)日:2013-08-27
申请号:US13441451
申请日:2012-04-06
申请人: Benoit Kenda , Yannick Quesnel , Ali Ates , Philippe Michel , Laurent Turet , Joel Mercier
发明人: Benoit Kenda , Yannick Quesnel , Ali Ates , Philippe Michel , Laurent Turet , Joel Mercier
IPC分类号: A01N43/58 , A01N43/60 , A01N43/90 , A01N43/42 , A01N43/40 , A01N43/82 , A61K31/50 , A61K31/495 , A61K31/501 , A61K31/519 , A61K31/52 , A61K31/44
CPC分类号: C07D513/04 , C07D401/06 , C07D403/06 , C07D413/06 , C07D417/06 , C07D471/04 , C07D473/00 , C07D487/04
摘要: The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
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公开(公告)号:US20080081832A1
公开(公告)日:2008-04-03
申请号:US11808558
申请日:2007-06-11
申请人: Benoit Kenda , Philippe Michel , Yannick Quesnel
发明人: Benoit Kenda , Philippe Michel , Yannick Quesnel
IPC分类号: A61K31/4178 , A61K31/4184 , A61P25/00 , C07D403/06 , G01N33/53
CPC分类号: C07D207/263 , C07D207/27 , C07D403/08
摘要: The present invention relates to imidazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
摘要翻译: 本发明涉及咪唑衍生物,其制备方法,含有它们的药物组合物及其作为药物的用途。
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公开(公告)号:US07244747B2
公开(公告)日:2007-07-17
申请号:US10999217
申请日:2004-11-30
申请人: Benoit Kenda , Philippe Michel , Yannick Quesnel
发明人: Benoit Kenda , Philippe Michel , Yannick Quesnel
IPC分类号: A61K31/4178 , C07D403/06 , A61K31/4184 , A61K31/4409 , C07D401/14 , C07D403/13
CPC分类号: C07D207/263 , C07D207/27 , C07D403/08
摘要: The present invention relates to imidazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
摘要翻译: 本发明涉及咪唑衍生物,其制备方法,含有它们的药物组合物及其作为药物的用途。
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公开(公告)号:US20060258704A1
公开(公告)日:2006-11-16
申请号:US11453088
申请日:2006-06-15
申请人: Philippe Michel , Benoit Kenda
发明人: Philippe Michel , Benoit Kenda
IPC分类号: A61K31/453 , A61K31/445 , C07D211/56 , C07D409/02
CPC分类号: C07D409/04 , C07D211/76 , C07D211/78 , C07D223/10
摘要: This invention relates to new 2-oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivatives of formula (1) having anticonvulsant activity which are useful as therapeutic agents for the treatment or prevention of epilepsy and other neurological disorders. The invention also concerns processes for preparing these derivatives and novel intermediates used in the preparation of these derivatives.
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公开(公告)号:US20050137241A1
公开(公告)日:2005-06-23
申请号:US10999217
申请日:2004-11-30
申请人: Benoit Kenda , Philippe Michel , Yannick Quesnel
发明人: Benoit Kenda , Philippe Michel , Yannick Quesnel
IPC分类号: C07D207/26 , C07D207/263 , C07D207/27 , C07D403/06 , C07D403/08 , A61K31/4184 , A61K31/4178 , C07D43/02
CPC分类号: C07D207/263 , C07D207/27 , C07D403/08
摘要: The present invention relates to imidazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
摘要翻译: 本发明涉及咪唑衍生物,其制备方法,含有它们的药物组合物及其作为药物的用途。
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10.New Heterocyclic Derivatives Useful For The Treatment of CNS Disorders 审中-公开
标题翻译: 用于治疗CNS疾病的新型杂环衍生物公开(公告)号:US20100222326A1
公开(公告)日:2010-09-02
申请号:US12597772
申请日:2008-04-24
申请人: Benoit Kenda , Laurent Turet , Yannick Quesnel , Philippe Michel , Ali Ates
发明人: Benoit Kenda , Laurent Turet , Yannick Quesnel , Philippe Michel , Ali Ates
IPC分类号: A61K31/55 , A61K31/4164 , A61K31/421 , A61K31/40 , A61K31/426 , A61K31/5025 , A61K31/454 , A61K31/437 , A61K31/4178 , A61K31/4725 , A61K31/4709 , A61P25/00 , A61P25/16 , A61P25/24 , A61P25/22 , A61P25/06 , A61P9/00 , A61P9/10 , A61P35/00 , C07D233/32 , C07D403/06 , C07D471/04 , C07D487/04 , C07D263/34 , C07D207/36 , C07D211/76 , C07D223/10 , C07D223/14 , C07D215/227 , C07D495/04
CPC分类号: C07D233/32 , A61K31/4015 , A61K31/407 , A61K31/4162 , A61K31/417 , A61K31/421 , A61K31/423 , A61K31/426 , A61K31/428 , A61K31/45 , A61K31/4704 , A61K31/472 , A61K31/55 , C07D215/227 , C07D217/24 , C07D263/20 , C07D263/22 , C07D263/38 , C07D277/14 , C07D277/34 , C07D277/68 , C07D401/06 , C07D403/06 , C07D417/06 , C07D471/04 , C07D487/04 , C07D495/04 , C07D519/00
摘要: The present invention relates to new compounds, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
摘要翻译: 本发明涉及新化合物,其制备方法,含有它们的药物组合物及其作为药物的用途。
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