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公开(公告)号：US20060089359A1
公开(公告)日：2006-04-27
申请号：US11233311
申请日：2005-09-23
申请人： Edward Boyd , Frederick Brookfield , Guy Georges , Bernhard Goller , Sabine Huensch , Petra Rueger , Matthias Rueth , Stefan Scheiblich , Christine Schuell , Wolfgang von der Saal , Justin Warne , Stefan Weigand
发明人： Edward Boyd , Frederick Brookfield , Guy Georges , Bernhard Goller , Sabine Huensch , Petra Rueger , Matthias Rueth , Stefan Scheiblich , Christine Schuell , Wolfgang von der Saal , Justin Warne , Stefan Weigand
IPC分类号： A61K31/502 , C07D403/02
CPC分类号： C07D403/12
摘要： Compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates are disclosed. Also disclosed are methods for the preparation of the above-mentioned compounds, pharmaceutical compositions containing them, as well as the use of the above-mentioned compounds in the treatment, control or prevention of illnesses such as cancer.
摘要翻译： 公开了式I化合物的药学上可接受的盐，对映体形式，非对映异构体和外消旋体。 还公开了制备上述化合物的方法，含有它们的药物组合物，以及上述化合物在治疗，控制或预防诸如癌症等疾病中的用途。
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公开(公告)号：US07226923B2
公开(公告)日：2007-06-05
申请号：US11233311
申请日：2005-09-23
申请人： Edward Boyd , Frederick Brookfield , Guy Georges , Bernhard Goller , Sabine Huensch , Petra Rueger , Matthias Rueth , Stefan Scheiblich , Christine Schuell , Wolfgang von der Saal , Justin Warne , Stefan Weigand
发明人： Edward Boyd , Frederick Brookfield , Guy Georges , Bernhard Goller , Sabine Huensch , Petra Rueger , Matthias Rueth , Stefan Scheiblich , Christine Schuell , Wolfgang von der Saal , Justin Warne , Stefan Weigand
IPC分类号： C07D403/12 , C07D403/14 , A61K31/502
CPC分类号： C07D403/12
摘要： Compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates are disclosed. Also disclosed are methods for the preparation of the above-mentioned compounds, pharmaceutical compositions containing them, as well as the use of the above-mentioned compounds in the treatment, control or prevention of illnesses such as cancer.
摘要翻译： 公开了式I化合物的药学上可接受的盐，对映体形式，非对映异构体和外消旋体。 还公开了制备上述化合物的方法，含有它们的药物组合物，以及上述化合物在治疗，控制或预防诸如癌症等疾病中的用途。
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公开(公告)号：US20060142247A1
公开(公告)日：2006-06-29
申请号：US11301993
申请日：2005-12-13
申请人： Guy Georges , Bernhard Goller , Klaus-Peter Kuenkele , Anja Limberg , Ulrike Reiff , Petra Rueger , Matthias Rueth , Christine Schuell
发明人： Guy Georges , Bernhard Goller , Klaus-Peter Kuenkele , Anja Limberg , Ulrike Reiff , Petra Rueger , Matthias Rueth , Christine Schuell
IPC分类号： C07F7/02 , A61K31/695 , A61K31/675 , C07D471/02
CPC分类号： C07D487/04 , C07D471/04
摘要： The present invention relates to the compounds of formula I their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing such compounds and their manufacture, as well as the use of such compounds in the control or prevention of illnesses such as cancer.
摘要翻译： 本发明涉及式I化合物其药学上可接受的盐或酯，对映体形式，非对映异构体和外消旋物，上述化合物的制备，含有这些化合物的药物组合物及其制备方法以及这些化合物的用途 控制或预防癌症等疾病。
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4.发明申请SUBSTITUTED INDAZOLE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS 审中-公开取代的吲哚衍生物，其制造和用作药物代理公开(公告)号：US20090291968A1
公开(公告)日：2009-11-26
申请号：US12293428
申请日：2007-03-21
申请人： Guy Georges , Bernhard Goller , Anja Limberg , Petra Rueger , Matthias Rueth , Christine Schuell , Mark Stahl
发明人： Guy Georges , Bernhard Goller , Anja Limberg , Petra Rueger , Matthias Rueth , Christine Schuell , Mark Stahl
IPC分类号： A61K31/4188 , C07D487/04 , A61K31/4196 , A61K31/4439 , A61K31/506
CPC分类号： C07D487/04
摘要： Objects of the present invention are the compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
摘要翻译： 本发明的目的是式I化合物，其药学上可接受的盐，对映体形式，非对映异构体和外消旋物，上述化合物的制备，含有它们的药物及其制备，以及上述化合物 控制或预防癌症等疾病。
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5.发明申请Tricyclic Lactam Derivatives, Their Manufacture and Use as Pharmaceutical Agents 审中-公开三环内酰胺衍生物，其制造和用作药剂公开(公告)号：US20090143375A1
公开(公告)日：2009-06-04
申请号：US12084531
申请日：2006-12-13
申请人： Guy Georges , Bernhard Goller , Hans-Willi Krell , Anja Limberg , Ulrike Reiff , Petra Rueger , Matthias Rueth , Christine Schuell , Mark Stahl
发明人： Guy Georges , Bernhard Goller , Hans-Willi Krell , Anja Limberg , Ulrike Reiff , Petra Rueger , Matthias Rueth , Christine Schuell , Mark Stahl
IPC分类号： A61K31/4188 , C07D487/04 , A61P29/00 , A61P9/00 , A61P35/00 , A61P25/00 , A61K31/5377
CPC分类号： C07D487/04
摘要： Objects of the present invention are the compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
摘要翻译： 本发明的目的是式I化合物，其药学上可接受的盐，对映体形式，非对映异构体和外消旋物，上述化合物的制备，含有它们的药物及其制备，以及上述化合物 控制或预防癌症等疾病。
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6.发明授权Thiazolidinediones alone or in combination with other therapeutic agents for inhibiting or reducing tumour growth 失效噻唑烷二酮单独或与其他治疗剂组合用于抑制或减少肿瘤生长公开(公告)号：US07323481B2
公开(公告)日：2008-01-29
申请号：US10474443
申请日：2002-04-04
IPC分类号： A61K31/425
CPC分类号： A61K31/425 , C07D417/12 , C07D417/14
摘要： Use of thiazolidinedione derivatives for the preparation of medicaments for inhibiting or reducing tumour growth or metastases, alone or in combination with an RXR agonist or well-known antitumour agent.
摘要翻译： 噻唑烷二酮衍生物用于制备用于抑制或减少肿瘤生长或转移的药物，单独或与RXR激动剂或众所周知的抗肿瘤剂组合。
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7.发明申请Thiazolidinediones alone or in combination with other therapeutic agents for inhibiting or reducing tumour growth 失效噻唑烷二酮单独或与其他治疗剂组合用于抑制或减少肿瘤生长公开(公告)号：US20050176787A1
公开(公告)日：2005-08-11
申请号：US10474443
申请日：2002-04-04
IPC分类号： A61K31/203 , A61K31/425 , A61K31/427 , A61P35/00 , A61P43/00 , C07D417/12 , C07D417/14
CPC分类号： A61K31/425 , C07D417/12 , C07D417/14
摘要： Use of thiazolidinedione derivatives for the preparation of medicaments for inhibiting or reducing tumour growth or metastases, alone or in combination with an RXR agonist or well-known antitumour agent.
摘要翻译： 噻唑烷二酮衍生物用于制备用于抑制或减少肿瘤生长或转移的药物，单独或与RXR激动剂或众所周知的抗肿瘤剂组合。
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