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公开(公告)号:US06541449B1
公开(公告)日:2003-04-01
申请号:US09749504
申请日:2000-12-26
IPC分类号: A61K3714
CPC分类号: C07K14/805 , A01N1/02 , A01N1/0226 , A01N1/0231 , A61J1/05 , A61K38/42 , B32B15/08 , B32B27/08
摘要: The present invention relates to a method of therapeutically, or prophylactically, treating a vertebrate to increase tissue oxygenation, or maintain issue oxygenation, in tissue of a vertebrate wherein the tissue has a reduced red blood cell flow, and wherein the vertebrate has a normovolemic blood volume and at least a normal systemic vascular resistance. The method comprises introducing into the circulatory system of the vertebrate at least one dose of hemoglobin.
摘要翻译: 本发明涉及一种在脊椎动物组织中治疗或预防性地治疗脊椎动物以增加组织氧合或维持问题氧合的方法,其中所述组织具有减少的红细胞流,并且其中所述脊椎动物具有正常血容量的血液 体积和至少一个正常的全身血管阻力。 该方法包括向脊椎动物的循环系统中引入至少一种剂量的血红蛋白。
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公开(公告)号:US5854209A
公开(公告)日:1998-12-29
申请号:US409337
申请日:1995-03-23
IPC分类号: A01N1/02 , A61J1/00 , A61J1/05 , A61K38/00 , A61K38/42 , B32B15/08 , B32B27/08 , C07K14/805 , C07K1/18
CPC分类号: C07K14/805 , A01N1/02 , A01N1/0226 , A01N1/0231 , A61K38/42 , B32B15/08 , B32B27/08 , A61J1/05
摘要: The present invention relates to a method of therapeutically, or prophylactically, treating a vertebrate to increase tissue oxygenation, or maintain issue oxygenation, in tissue of a vertebrate wherein the tissue has a reduced red blood cell flow, and wherein the vertebrate has a normovolemic blood volume and at least a normal systemic vascular resistance. The method comprises introducing into the circulatory system of the vertebrate at least one dose of hemoglobin.
摘要翻译: 本发明涉及一种在脊椎动物组织中治疗或预防性地治疗脊椎动物以增加组织氧合或维持问题氧合的方法,其中所述组织具有减少的红细胞流,并且其中所述脊椎动物具有正常血容量的血液 体积和至少一个正常的全身血管阻力。 该方法包括向脊椎动物的循环系统中引入至少一种剂量的血红蛋白。
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公开(公告)号:US07267817B2
公开(公告)日:2007-09-11
申请号:US10967475
申请日:2004-10-18
CPC分类号: A01N1/0226 , A01N1/02 , A61K35/18 , A61K38/42 , A61K2300/00
摘要: A method of treatment of a patient includes administering to the patient stored red blood cells and a hemoglobin solution. The stored red blood cells and the hemoglobin solution can be administered to the patient simultaneously. Alternatively, the hemoglobin solution can be administered to the patient prior to administrating the stored red blood cells or the stored red blood cells can be administered to the patient prior to administering the hemoglobin solution. A composition of the invention includes stored red blood cells and a hemoglobin solution.
摘要翻译: 治疗患者的方法包括向患者施用储存的红细胞和血红蛋白溶液。 储存的红细胞和血红蛋白溶液可以同时给予患者。 或者,可以在给予所存储的红细胞之前将血红蛋白溶液施用于患者,或者在施用血红蛋白溶液之前将所存储的红细胞施用于患者。 本发明的组合物包括储存的红细胞和血红蛋白溶液。
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公开(公告)号:US06811778B2
公开(公告)日:2004-11-02
申请号:US09950270
申请日:2001-09-10
IPC分类号: A01N6300
CPC分类号: A01N1/0226 , A01N1/02 , A61K35/18 , A61K38/42 , A61K2300/00
摘要: A method of treatment of a patient includes administering to the patient stored red blood cells and a hemoglobin solution. The stored red blood cells and the hemoglobin solution can be administered to the patient simultaneously. Alternatively, the hemoglobin solution can be administered to the patient prior to administrating the stored red blood cells or the stored red blood cells can be administered to the patient prior to administering the hemoglobin solution. A composition of the invention includes stored red blood cells and a hemoglobin solution.
摘要翻译: 治疗患者的方法包括向患者施用储存的红细胞和血红蛋白溶液。 储存的红细胞和血红蛋白溶液可以同时给予患者。 或者,可以在给予所存储的红细胞之前将血红蛋白溶液施用于患者,或者在施用血红蛋白溶液之前将所存储的红细胞施用于患者。 本发明的组合物包括储存的红细胞和血红蛋白溶液。
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