公开(公告)号：US20090086895A1

公开(公告)日：2009-04-02

申请号：US11906156

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. Wood

IPC分类号： G01N23/223

CPC分类号： G01N23/223 ,  G01N2223/076

摘要： One aspect relates to determining a location of an at least one X-ray fluorescing event occurring within an at least some matter of at least a portion of an individual, wherein the determining the location of the at least one X-ray fluorescing event is based at least in part on determining a relative angle at which an at least one applied high energy photon and/or particle is being applied to the at least some matter of the at least the portion of the individual, a relative position from which an at least one applied high energy photon and/or particle is being applied to the at least some matter of the at least the portion of the individual, a detected location of an at least one induced fluorescing X-ray photon fluoresced during the at least one X-ray fluorescing event, and a received angle at which the at least one induced fluorescing X-ray photon is received.

摘要翻译： 一个方面涉及确定发生在个体至少一部分的至少一部分内的至少一个X射线荧光事件的位置，其中确定至少一个X射线发荧光事件的位置是基于 至少部分地基于确定至少一个所施加的高能量光子和/或颗粒被施加到所述至少所述个体的所述部分中的所述至少一些物质的相对角度，相对位置至少一个 一个应用的高能量光子和/或粒子被施加到个体的至少一部分的至少一些物质，在至少一个X射线照射期间发现荧光的至少一个感应的荧光X射线光子的检测位置， 射线荧光事件和接收至少一个感应的荧光X射线光子的接收角度。

公开(公告)号：US20090086894A1

公开(公告)日：2009-04-02

申请号：US11906150

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood Jr. ,  Victoria Y.H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood Jr. ,  Victoria Y.H. Wood

IPC分类号： H05G1/26 ,  G01N23/223 ,  G01N23/225

CPC分类号： G01N23/223 ,  A61B6/00 ,  A61B6/4021 ,  A61B6/4291 ,  A61B6/485 ,  G01N2223/076 ,  G01N2223/506

摘要： One aspect can relate to determining a total time of flight that indicates an at least one applied duration and an at least one induced duration, wherein the at least one applied duration describes the time for an at least some pulse-type input energy to be applied from a transmission location to an at least one X-ray fluorescing event in the at least some matter of the at least the portion of the at least one individual, and wherein the at least one induced duration describes the time for an at least one induced X-ray fluorescing photon, to travel from the at least one X-ray fluorescing event in the at least some matter of the at least the portion of the at least one individual to a location where the at least one induced X-ray fluorescing photon is received at least partially by a detecting the at least one induced X-ray fluorescing photon. The aspect can relate to determining a location information of the at least one X-ray fluorescing event in the at least some matter of the at least the portion of the at least one individual based at least partially on the total time of flight.

摘要翻译： 一个方面可以涉及确定指示至少一个施加持续时间和至少一个诱导持续时间的总飞行时间，其中所述至少一个施加的持续时间描述了应用至少一些脉冲型输入能量的时间 在所述至少一个个体的至少一部分的至少一些物质中从透射位置到至少一个X射线荧光事件，并且其中所述至少一个诱导持续时间描述至少一个诱导的时间 X射线荧光光子从所述至少一个个体的至少一部分中的至少一些物质中的至少一个X射线荧光事件行进到至少一个诱导的X射线荧光光子的位置 至少部分地通过检测至少一个诱导的X射线荧光光子被接收。 该方面可以涉及至少部分地基于总飞行时间来确定至少一个个体的至少一部分的至少一些事件中的至少一个X射线荧光事件的位置信息。

公开(公告)号：US08041005B2

公开(公告)日：2011-10-18

申请号：US11906161

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/223

CPC分类号： G01N23/223 ,  G01N2223/076

摘要： One aspect relates to inducing at least one induced X-ray fluorescing photon within an at least some matter of an at least a portion of an at least one individual responsive to a substantial single input energy event based at least partially on an at least some input energy being applied to the at least some matter of the at least the portion of the at least one individual; and detecting the at least one induced X-ray fluorescing photon; and X-ray fluorescence visualizing, imaging, or information providing within the at least some matter of the at least the portion of the at least one individual responsive to the detecting the at least one induced X-ray fluorescing photon.

摘要翻译： 一个方面涉及至少部分地基于至少一些输入而在至少一个个体的至少一部分的至少一些物质内诱导至少一个诱导的X射线荧光光子，所述至少一个个体响应于基本的单个输入能量事件 能量被施加到至少一个个体的至少一部分的至少一些物质; 以及检测所述至少一个诱导的X射线荧光光子; 以及响应于检测所述至少一个诱导的X射线荧光光子，在所述至少一个个体的至少一部分的至少一些物质内提供X射线荧光可视化，成像或信息。

公开(公告)号：US07724867B2

公开(公告)日：2010-05-25

申请号：US11906135

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/223

CPC分类号： A61B6/503 ,  A61B5/415 ,  A61B5/418 ,  A61B5/489 ,  A61B6/12 ,  A61B6/14 ,  A61B6/4021 ,  A61B6/4291 ,  A61B6/482 ,  A61B6/485 ,  A61B6/50 ,  A61B6/501 ,  A61B6/502 ,  A61B6/504 ,  A61B6/505 ,  A61B6/506 ,  A61B6/507 ,  A61B6/508 ,  A61B2503/40 ,  G01N23/223 ,  G01N2223/076

摘要： One aspect relates to detecting at least one induced X-ray fluorescing photon fluoresced from substantially within an at least some matter of an at least a portion of an at least one individual at least partially as a result of receiving at least one induced X-ray fluorescing photon generated at least partially within at least one X-ray fluorescence event within the at least some matter of the at least the portion of the at least one individual which has been generated responsive to an at least some input energy resulting from a single input energy event, wherein the at least one induced X-ray fluorescing photon that has passed through the at least some matter of the at least the portion of the at least one individual is at a level to substantially limit interference between the at least one induced X-ray fluorescing photon with an at least one other induced X-ray fluorescing photon that travel for distances greater than a prescribed limit through the at least some matter of the at least the portion of the at least one individual, wherein the at least one other induced X-ray fluorescing photon attenuates by a prescribed percentage after passing through the prescribed distance through the at least some matter of the at least the portion of the at least one individual.

摘要翻译： 一个方面涉及至少部分地检测至少一个感兴趣的X射线荧光光子，其基本上在至少一个个体的至少一部分的至少一些物质内发射，作为接收至少一个诱导X射线 至少部分地在至少一个X射线荧光事件中产生荧光光子，所述至少一个X射线荧光事件在所述至少一个个体的至少一部分中的至少一些物质中响应于由单个输入产生的至少一些输入能量而产生 能量事件，其中已经通过所述至少一个个体的至少一部分的至少一些物质的所述至少一个感兴趣的X射线荧光光子处于基本上限制所述至少一个诱导X 具有至少一个其它诱导的X射线荧光光子的荧光光子，其行进距离大于规定的极限，通过至少一些事件 所述至少一个个体的部分，其中所述至少一个其它诱导的X射线荧光光子在经过所述规定距离之后通过所述至少一个的所述至少一部分的所述至少一些物质衰减预定百分比 个人。

公开(公告)号：US07711089B2

公开(公告)日：2010-05-04

申请号：US11786776

申请日：2007-04-11

申请人： Edward S. Boyden ,  Glenn B. Foster ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Glenn B. Foster ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/201

CPC分类号： G01N23/201

摘要： A visualization or imaging system involves inducing and/or detecting Compton scattered X-rays to provide information or a visual representation of a portion of an individual. In one approach, the Compton scattered X-rays are converted to a visible or detectible representations through scintillation.

摘要翻译： 可视化或成像系统包括诱导和/或检测康普顿散射的X射线以提供个体的一部分的信息或视觉表示。 在一种方法中，康普顿散射的X射线通过闪烁转换为可见或可检测的表示。

公开(公告)号：US07664224B2

公开(公告)日：2010-02-16

申请号：US12002287

申请日：2007-12-14

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/223

CPC分类号： G01N23/223 ,  G01N2223/076

摘要： One aspect can relate to detecting a presence of an at least one chemical, compound, or biological material contained in an at least some matter of an at least a portion of an at least one individual based at least partially on addition of an at least one chemical identifying additive to the at least some matter of the at least the portion of the at least one individual based at least partially on a generation of an at least one induced X-ray fluorescing photon within the at least one chemical identifying additive responsive to a single input energy event in which an at least some input energy is being applied proximal to the at least one chemical, compound, or biological material contained in the at least some matter of the at least the portion of the at least one individual.

摘要翻译： 一个方面可以涉及至少部分地基于添加至少一个个体的至少一个个体的至少一部分的至少一些物质中的至少一种化学，化合物或生物材料的存在来检测 至少部分地至少部分地基于在所述至少一种化学鉴定添加剂中产生至少一种诱导的X射线荧光光子的化学鉴定添加剂至少部分至少一部分物质的化学鉴定添加剂，其响应于 单输入能量事件，其中至少一些输入能量被施加在至少一个化学，化合物或生物材料的近端，该至少一种化学，化合物或生物材料包含在至少一个个体的至少一部分的该至少一些物质中。

公开(公告)号：US07653173B2

公开(公告)日：2010-01-26

申请号：US11906142

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/223

CPC分类号： G01N23/223 ,  G01N2223/076

摘要： One aspect relates to deriving at least one first X-ray fluorescence visualization, image, or provided information substantially within an at least some matter of an at least a portion of an at least one individual at least partially as a result of directing an at least one first applied high energy photon and/or particle having an at least one first input energy towards the at least some matter of the at least the portion of the at least one individual. The aspect comprises deriving at least one second X-ray fluorescence visualization, image, or provided information substantially within the at least some matter of the at least the portion of the at least one individual at least partially as a result of directing an at least one second applied high energy photon and/or particle having an at least one second input energy toward the at least some matter of the at least the portion of the at least one individual. The aspect comprises deriving an at least one combined X-ray fluorescence visualization, combined image, or combined provided information at least partially by combining the at least one first X-ray fluorescence visualization, image, or provided information with the at least one second X-ray fluorescence visualization, image, or provided information.

摘要翻译： 一方面涉及至少部分地至少部分地导出至少一个第一X射线荧光可视化，图像或提供的信息，所述至少一个第一X射线荧光可视化，图像或提供的信息基本上在至少一个个体的至少一部分的至少一部分内， 首先将至少一个第一输入能量的高能光子和/或粒子应用于至少一个个体的至少一部分的至少一些物质。 该方面包括至少部分地至少部分地导出至少一个第二X射线荧光可视化，图像或提供的信息，所述至少一个第二X射线荧光可视化，图像或提供的信息基本上在所述至少一个个体的该至少一部分的至少一些事物内，作为指导至少一个 第二施加的高能量光子和/或具有至少一个第二输入能量的颗粒朝向至少一个个体的至少一部分的至少一些物质。 该方面包括至少部分地通过将至少一个第一X射线荧光可视化，图像或提供的信息与至少一个第二X射线荧光可视化，组合图像或组合提供的信息， 荧光可视化，图像或提供的信息。

公开(公告)号：US20090086905A1

公开(公告)日：2009-04-02

申请号：US11906161

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

IPC分类号： G01N23/223

CPC分类号： G01N23/223 ,  G01N2223/076

摘要： One aspect relates to inducing at least one induced X-ray fluorescing photon within an at least some matter of an at least a portion of an at least one individual responsive to a substantial single input energy event based at least partially on an at least some input energy being applied to the at least some matter of the at least the portion of the at least one individual; and detecting the at least one induced X-ray fluorescing photon; and X-ray fluorescence visualizing, imaging, or information providing within the at least some matter of the at least the portion of the at least one individual responsive to the detecting the at least one induced X-ray fluorescing photon.

摘要翻译： 一个方面涉及至少部分地基于至少一些输入而在至少一个个体的至少一部分的至少一些物质内诱导至少一个诱导的X射线荧光光子，所述至少一个个体响应于基本的单个输入能量事件 能量被施加到至少一个个体的至少一部分的至少一些物质; 以及检测所述至少一个诱导的X射线荧光光子; 以及响应于检测所述至少一个诱导的X射线荧光光子，在所述至少一个个体的至少一部分的至少一些物质内提供X射线荧光可视化，成像或信息。

公开(公告)号：US20090086899A1

公开(公告)日：2009-04-02

申请号：US11906096

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

IPC分类号： G01B15/02

CPC分类号： G01N23/223 ,  A61B5/445 ,  A61B6/12 ,  A61B6/483 ,  A61B6/485 ,  A61B6/488 ,  A61B6/503 ,  A61B6/504 ,  A61B6/505 ,  A61B6/506 ,  A61B6/507 ,  A61B6/508 ,  G01N2223/076

摘要： One aspect can relate to performing a first X-ray fluorescence visualizing, imaging, or information providing within a first field of view in an at least some matter of an at least a portion of an at least one individual based on at least one induced fluorescing X-ray photon. The aspect can include operationally repositioning the first X-ray fluorescence visualizing, imaging, or information providing to X-ray fluorescence visualize, image, or information provide from within the first field of view to within a second field of view. The aspect can include performing a second X-ray fluorescence visualizing, imaging, or information providing within the second field of view within the at least some matter of the at least the portion of the at least one individual.

摘要翻译： 一个方面可以涉及在至少一个个体的至少一部分的至少一些物质中，基于至少一种诱导的荧光发射来执行在第一视野内提供第一X射线荧光可视化，成像或信息 X射线光子。 该方面可以包括将第一X射线荧光可视化，成像或提供给第一视野内的X射线荧光可视化，图像或信息的信息重新定位到第二视场内。 该方面可以包括在至少一个个体的至少一部分的至少一些事项内执行第二视场内的第二X射线荧光可视化，成像或提供信息。

公开(公告)号：US07773722B2

公开(公告)日：2010-08-10

申请号：US11906155

申请日：2007-09-28

申请人： Edward S. Boyden ,  Glenn B. Foster ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Glenn B. Foster ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/223

CPC分类号： G01N23/223 ,  A61B5/415 ,  A61B5/418 ,  A61B5/489 ,  A61B6/12 ,  A61B6/14 ,  A61B6/4021 ,  A61B6/4291 ,  A61B6/482 ,  A61B6/485 ,  A61B6/50 ,  A61B6/501 ,  A61B6/502 ,  A61B6/503 ,  A61B6/504 ,  A61B6/505 ,  A61B6/506 ,  A61B6/507 ,  A61B6/508 ,  A61B2503/40 ,  G01N2223/076

摘要： One aspect relates to inducing at least one induced X-ray fluorescing photon at a X-ray fluorescence event within an at least some matter of an at least a portion of an at least one individual responsive to an at least some input energy being applied to the at least some matter of the at least the portion of the at least one individual. The aspect can relate to detecting the at least one induced X-ray fluorescing photon, wherein the inducing at least one induced X-ray fluorescing photon and the detecting the at least one induced X-ray fluorescing photon is configured to be performed at least partially with at least one device which is configured to be transported portably by a person.

摘要翻译： 一个方面涉及在至少一个个体的至少一部分的至少一部分内的X射线荧光事件处诱导至少一个诱导的X射线荧光光子，所述至少一个个体响应至少一些输入能量被施加到 所述至少一个个体的至少一部分的至少一些物质。 该方面可以涉及检测至少一个诱导的X射线荧光光子，其中诱导至少一个诱导的X射线荧光光子和检测至少一个诱导的X射线荧光光子被配置为至少部分地进行 其中至少一个设备被配置为可由个人便携式地传送。