公开(公告)号：US12268593B2

公开(公告)日：2025-04-08

申请号：US17334464

申请日：2021-05-28

Applicant: Edwards Lifesciences Corporation

Inventor： Dustin P. Armer ,  Sean Chow ,  Jenny Nguyen ,  Emil Karapetian ,  Tri D. Tran

IPC: A61F2/24

Abstract: Anchor devices and methods used to secure a prosthetic valve to a native valve annulus are described. The anchor device can be a separate expandable element from the prosthetic valve that is first advanced to the annulus and deployed, after which an expandable prosthetic valve is advanced to within the annulus and deployed. The combination of the two elements can apply a clamping force to the valve leaflets which holds the prosthetic valve in place. The anchor device can have a lower or ventricular portion and an upper or atrial portion. The anchor device can include one or more leaflet clamping portions. One, two, or more upstanding vertical posts between the clamping portions can extend upward at the valve commissures and support the upper portion, which can include one or more structures for leak prevention.

公开(公告)号：US20240099839A1

公开(公告)日：2024-03-28

申请号：US18536042

申请日：2023-12-11

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Tri D. Tran ,  Ronaldo C. Cayabyab ,  David J. Evans ,  Sean Chow ,  Christopher Chia ,  Tamir S. Levi

IPC: A61F2/24 ,  A61F2/958

CPC classification number: A61F2/2433 ,  A61F2/958 ,  A61M25/10184

Abstract: A delivery apparatus for a prosthetic heart valve includes a shaft, an inner balloon, and an outer balloon. The shaft has a lumen extending from a proximal end portion to a distal end portion and a plurality of openings formed in the distal end portion. The shaft is configured such that a fluid can flow through the lumen and the openings. The inner balloon has end portions and a center portion disposed between the end portions. The inner balloon is mounted on the distal end portion of the shaft and is in fluid communication with the openings of the shaft. When the inner balloon is inflated with the fluid, the end portions expand farther radially outwardly than the center portion. The outer balloon is mounted to the shaft and disposed over the inner balloon. The outer balloon is configured to fully expand after the inner balloon at least partially expands.

公开(公告)号：US20230157815A1

公开(公告)日：2023-05-25

申请号：US18153182

申请日：2023-01-11

Applicant: Edwards Lifesciences Corporation

Inventor： Tri D. Tran ,  Adeeb Saiduddin ,  Ronaldo C. Cayabyab

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2/2436 ,  A61F2250/0063 ,  A61M25/0054

Abstract: An anchoring device that can be positioned within a native valve, such as the native mitral valve, to secure a replacement prosthetic valve in place. The anchoring device can comprise a docking station formed of an elastic tube-like member defining a generally coiled shape. The docking station can have an atrial or stabilization turn, a leading or encircling turn, and a central region. In many embodiments, the docking device possess a plurality of cuts on opposing sides of the tube-like member to allow biasing of the member.

公开(公告)号：US11026781B2

公开(公告)日：2021-06-08

申请号：US16691244

申请日：2019-11-21

Applicant: Edwards Lifesciences Corporation

Inventor： Dustin P. Armer ,  Sean Chow ,  Jenny Nguyen ,  Emil Karapetian ,  Tri D. Tran

IPC: A61F2/24

Abstract: Anchor devices and methods can be used to secure a prosthetic valve to a native valve annulus. The anchor device can be a separate expandable element from the prosthetic valve that is first advanced to the annulus and deployed, after which an expandable prosthetic valve is advanced to within the annulus and deployed. The combination of the two elements can apply a clamping force to the valve leaflets which holds the prosthetic valve in place. The anchor device can have a lower or ventricular portion and an upper or atrial portion. The anchor device can include one or more leaflet clamping portions. One, two, or more upstanding vertical posts between the clamping portions can extend upward at the valve commissures and support the upper portion, which can include one or more structures for leak prevention.

公开(公告)号：US20210085458A1

公开(公告)日：2021-03-25

申请号：US17111148

申请日：2020-12-03

Applicant: Edwards Lifesciences Corporation

Inventor： Tri D. Tran ,  Ronaldo C. Cayabyab ,  David J. Evans ,  Sean Chow ,  Christopher Chia ,  Tamir S. Levi

IPC: A61F2/24 ,  A61F2/958

Abstract: A delivery apparatus for a prosthetic heart valve includes a shaft, an inner balloon, and an outer balloon. The shaft has a lumen extending from a proximal end portion to a distal end portion and a plurality of openings formed in the distal end portion. The shaft is configured such that a fluid can flow through the lumen and the openings. The inner balloon has end portions and a center portion disposed between the end portions. The inner balloon is mounted on the distal end portion of the shaft and is in fluid communication with the openings of the shaft. When the inner balloon is inflated with the fluid, the end portions expand farther radially outwardly than the center portion. The outer balloon is mounted to the shaft and disposed over the inner balloon. The outer balloon is configured to fully expand after the inner balloon at least partially expands.

公开(公告)号：US10940000B2

公开(公告)日：2021-03-09

申请号：US15984661

申请日：2018-05-21

Applicant: Edwards Lifesciences Corporation

Inventor： Darshin S. Patel ,  Boaz Manash ,  Tri D. Tran ,  Ofir Witzman ,  Yoav Rozen ,  Alexander J. Siegel ,  David M. Taylor

IPC: A61F2/24

Abstract: A delivery catheter is in various embodiments configured to deliver an anchoring device to a native valve annulus of a patient's heart, where the anchoring device can better secure a prosthesis at the native annulus. The delivery catheter can includes a distal section that includes one or more spines or is laser cut to assume a particular shape for better facilitating delivery of the anchoring device at the implant site and can include a flexible tube, a first pull wire, and a second pull wire. The flexible tube can comprise a bore extending between the first end and the second end sized for passing the anchoring device therethrough. The distal portion can comprise a first flexing section and a second flexing section. Actuation of the first pull wire and the second pull wire can cause the flexible tube to move from a first configuration to a second configuration.

公开(公告)号：US20190298518A1

公开(公告)日：2019-10-03

申请号：US16447708

申请日：2019-06-20

Applicant: Edwards Lifesciences Corporation

Inventor： Gilbert Madrid ,  Matthew T. Winston ,  Sam Sok ,  Thanh Huy Le ,  Tri D. Tran ,  Kim Le ,  Michael D. Franklin

IPC: A61F2/24 ,  A61M25/10 ,  A61M25/01 ,  A61M25/00

Abstract: A method of implanting a prosthetic heart valve includes advancing a distal end portion of a catheter shaft through a patient's vasculature. The distal end portion of the catheter shaft includes an expansion device. A prosthetic heart valve is mounted on the expansion device with the expansion device and the prosthetic heart valve in a compressed configuration. The method further includes positioning the distal end portion of the catheter shaft and the prosthetic heart valve to an implantation location, and expanding the prosthetic heart valve and the expansion device from the compressed configuration to an expanded configuration. The expansion device includes an inner expandable member and a plurality of outer expandable members. The outer expandable members are distributed such that there are gaps providing perfusion passageways between the expansion device and the prosthetic heart valve when the expansion device is in the expanded configuration.

公开(公告)号：US20190269509A1

公开(公告)日：2019-09-05

申请号：US16415590

申请日：2019-05-17

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Ron Sharoni ,  Tamir S. Levi ,  Emil Karapetian ,  Tri D. Tran ,  Tung Le

IPC: A61F2/24 ,  B23P19/04 ,  A61F2/00 ,  B25B27/10 ,  A61B50/30 ,  B21D41/04 ,  B21D41/00 ,  B23P11/00 ,  A61B17/06

Abstract: A device for crimping a radially expandable and collapsible prosthetic valve comprises a crimping loop having a first end portion, a second end portion, and a loop portion extending between the first and second end portions and defining an opening configured to receive the prosthetic valve. The crimping loop is movable between a first state in which the opening has a first diameter and a second state in which the opening has a second diameter smaller than the first diameter such that when the prosthetic valve is positioned within the loop portion, movement of the crimping loop from the first state to the second state is effective to reduce a diameter of the prosthetic valve. A method for crimping a prosthetic valve comprises reducing a diameter of an opening of a crimping loop, thereby radially compressing an at least partially expanded prosthetic valve disposed within the opening.

公开(公告)号：US10327897B2

公开(公告)日：2019-06-25

申请号：US15085842

申请日：2016-03-30

Applicant: Edwards Lifesciences Corporation

Inventor： Gilbert Madrid ,  Matthew T. Winston ,  Sam Sok ,  Thanh Huy Le ,  Tri D. Tran ,  Kim Le ,  Michael D. Franklin

IPC: A61F2/24 ,  A61F2/958 ,  A61M25/00 ,  A61M25/01 ,  A61M25/10

Abstract: A delivery system for stabilizing a catheter shaft across an aortic arch can include one or more stabilizing members configured to fix or stabilize the position of the catheter relative to the aortic arch of a patient.

公开(公告)号：US20160235532A1

公开(公告)日：2016-08-18

申请号：US15136735

申请日：2016-04-22

Applicant: Edwards Lifesciences Corporation

Inventor： Tri D. Tran ,  Ronaldo C. Cayabyab ,  David J. Evans ,  Sean Chow ,  Christopher Chia

IPC: A61F2/24

CPC classification number: A61F2/2433 ,  A61F2/958 ,  A61F2002/485 ,  A61F2002/9517 ,  A61F2002/9586 ,  A61F2250/0003 ,  A61F2250/0021 ,  A61M25/1002 ,  A61M25/10184 ,  A61M2025/1013 ,  A61M2025/1084

Abstract: Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.