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公开(公告)号：US20180044285A1
公开(公告)日：2018-02-15
申请号：US15791814
申请日：2017-10-24
Applicant: Eisai R&D Management Co., Ltd.
Inventor： George Anthony Moniz , Annie Zhu Wilcoxen , Farid Benayoud , Toshiaki Tanaka , Keiichi Sorimachi
IPC: C07C309/73 , C12P7/22 , C07C309/66 , C07C303/28 , C07C33/50 , C07D239/34 , C07D401/12 , C07C69/16 , C07C303/44 , C07C29/147
CPC classification number: C07C309/73 , C07B2200/07 , C07C29/147 , C07C69/16 , C07C303/28 , C07C303/44 , C07C309/66 , C07C2601/02 , C07D239/34 , C07D401/12 , C12P7/22 , C07C33/50
Abstract: The present disclosure provides compounds and methods that are useful for the preparation of compounds useful as orexin-2 receptor antagonists.
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2.发明授权Methods and compounds useful in the synthesis of orexin-2 receptor antagonists 有权用于合成食欲肽-2受体拮抗剂的方法和化合物公开(公告)号：US09416109B2
公开(公告)日：2016-08-16
申请号：US14379063
申请日：2013-02-14
Applicant: Eisai R&D Management Co., Ltd.
Inventor： George Anthony Moniz , Annie Zhu Wilcoxen , Farid Benayoud , Jaemoon Lee , Huiming Zhang , Taro Terauchi , Ayumi Takemura , Yu Yoshida , Toshiaki Tanaka , Keiichi Sorimachi , Yoshimitsu Naoe , Yuji Kazuta
IPC: C07D239/34 , C07C69/16 , C07C309/66 , C12P7/22 , C07C309/73 , C07D401/12 , C07C303/28 , C07C29/147
CPC classification number: C07C309/73 , C07B2200/07 , C07C29/147 , C07C69/16 , C07C303/28 , C07C303/44 , C07C309/66 , C07C2601/02 , C07D239/34 , C07D401/12 , C12P7/22 , C07C33/50
Abstract: The present disclosure provides compounds and methods that are useful for the preparation of compounds useful as orexin-2 receptor antagonists.
Abstract translation: 本公开提供了可用于制备可用作食欲素-2受体拮抗剂的化合物的化合物和方法。
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公开(公告)号：US09828336B2
公开(公告)日：2017-11-28
申请号：US15158687
申请日：2016-05-19
Applicant: Eisai R&D Management Co., Ltd.
Inventor： George Anthony Moniz , Annie Zhu Wilcoxen , Farid Benayoud , Toshiaki Tanaka , Keiichi Sorimachi
IPC: C07C309/73 , C07C303/44 , C07C309/66 , C07C69/16 , C12P7/22 , C07D401/12 , C07D239/34 , C07C303/28 , C07C29/147
CPC classification number: C07C309/73 , C07B2200/07 , C07C29/147 , C07C69/16 , C07C303/28 , C07C303/44 , C07C309/66 , C07C2601/02 , C07D239/34 , C07D401/12 , C12P7/22 , C07C33/50
Abstract: The present disclosure provides compounds and methods that are useful for the preparation of compounds useful as orexin-2 receptor antagonists.
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4.发明申请METHODS AND COMPOUNDS USEFUL IN THE SYNTHESIS OF OREXIN-2 RECEPTOR ANTAGONISTS 审中-公开合成OREXIN-2受体拮抗剂的方法和化合物公开(公告)号：US20160318858A1
公开(公告)日：2016-11-03
申请号：US15158687
申请日：2016-05-19
Applicant: Eisai R&D Management Co., Ltd.
Inventor： George Anthony Moniz , Annie Zhu Wilcoxen , Farid Benayoud , Toshiaki Tanaka , Keiichi Sorimachi
IPC: C07C309/73 , C07C303/44 , C12P7/22 , C07C303/28
CPC classification number: C07C309/73 , C07B2200/07 , C07C29/147 , C07C69/16 , C07C303/28 , C07C303/44 , C07C309/66 , C07C2601/02 , C07D239/34 , C07D401/12 , C12P7/22 , C07C33/50
Abstract: The present disclosure provides compounds and methods that are useful for the preparation of compounds useful as orexin-2 receptor antagonists.
Abstract translation: 本公开提供了可用于制备可用作食欲素-2受体拮抗剂的化合物的化合物和方法。
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