公开(公告)号：US20250051322A1

公开(公告)日：2025-02-13

申请号：US18722917

申请日：2023-01-12

Applicant: Eisai R&D Management Co., Ltd.

Inventor： Ikuo Kushida ,  Yoko Ito ,  So Yasui ,  Takashi Fukuyama ,  Nobuaki Sato ,  Taro Asaba

IPC: C07D451/02 ,  A61K31/506

Abstract: Crystals of compounds represented by formula (I) having potential as drug substances for pharmaceuticals, as well as salts of compounds represented by formula (I) and their crystals.

公开(公告)号：US11479552B2

公开(公告)日：2022-10-25

申请号：US17376452

申请日：2021-07-15

Applicant: Eisai R&D Management Co., Ltd.

Inventor： Yu Yoshida ,  Yoichi Kita ,  Makoto Kotake ,  Keiichi Sorimachi ,  Toshiyuki Ohfusa ,  Takafumi Motoki ,  Taro Asaba

IPC: C07D401/14 ,  C07D471/08

Abstract: Provided are compounds represented by the following formulas (I), (II), (III) and (IV) having orexin type 2 receptor-activating activity, or their pharmaceutically acceptable salts.