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公开(公告)号:US20180057499A1
公开(公告)日:2018-03-01
申请号:US15689481
申请日:2017-08-29
Applicant: Eisai R&D Management Co., Ltd.
Inventor: Richard Clark , Tetsuya Kawahara , Daisuke Iida , Shinsuke Hirota , Yasuaki Kamada , Toshiyuki Ohfusa , Naoki Yoneda , Fumiyoshi Matsuura , So Yasui
IPC: C07D487/04
CPC classification number: C07D487/04 , A61K31/519 , A61P17/06 , A61P29/00
Abstract: The compounds represented by formulas (I) to (XVIII) or pharmaceutically acceptable salts thereof.
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公开(公告)号:US20170137436A1
公开(公告)日:2017-05-18
申请号:US15346912
申请日:2016-11-09
Applicant: Eisai R&D Management Co., Ltd.
Inventor: Toshiki Kurokawa , Yu Yoshida , Kogyoku Shin , Yoshihisa Kobayashi , Hironori Fukumoto , Kunitoshi Takeda , Yoshiaki Ohashi , Makoto Kotake , Tomoyuki Shibuguchi , Toru Watanabe , Yoichi Kita , Shinsuke Hirota , Takashi Fukuyama , Yasuaki Kamada
IPC: C07D491/147 , C07D491/052
CPC classification number: C07D491/147 , C07D491/052
Abstract: Compounds represented by formulae (I) to (XXII) or pharmaceutically acceptable salts thereof:
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公开(公告)号:US10227349B2
公开(公告)日:2019-03-12
申请号:US15689481
申请日:2017-08-29
Applicant: Eisai R&D Management Co., Ltd.
Inventor: Richard Clark , Tetsuya Kawahara , Daisuke Iida , Shinsuke Hirota , Yasuaki Kamada , Toshiyuki Ohfusa , Naoki Yoneda , Fumiyoshi Matsuura , So Yasui
IPC: C07D487/04 , A61K31/519 , A61P17/06 , A61P29/00
Abstract: The disclosure provides pyrazolo[1,5-a]pyrimidine compounds, and pharmaceutically acceptable salts thereof, having protease-activated receptor 2 (PAR2) inhibitory action, pharmaceutical compositions containing the same, and methods of treatment using the same.
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公开(公告)号:US09738656B2
公开(公告)日:2017-08-22
申请号:US15346912
申请日:2016-11-09
Applicant: Eisai R&D Management Co., Ltd.
Inventor: Toshiki Kurokawa , Yu Yoshida , Kogyoku Shin , Yoshihisa Kobayashi , Hironori Fukumoto , Kunitoshi Takeda , Yoshiaki Ohashi , Makoto Kotake , Tomoyuki Shibuguchi , Toru Watanabe , Yoichi Kita , Shinsuke Hirota , Takashi Fukuyama , Yasuaki Kamada
IPC: C07D491/147 , C07D491/052
CPC classification number: C07D491/147 , C07D491/052
Abstract: Compounds represented by formulae (I) to (XXII) or pharmaceutically acceptable salts thereof:
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