-
公开(公告)号：US07655638B2
公开(公告)日：2010-02-02
申请号：US11600523
申请日：2006-11-15
CPC分类号： A61K31/7076 , C07D473/16 , C07H19/16
摘要： Disclosed are novel compounds that are partial and full A1 adenosine receptor agonists, useful for treating various disease states, in particular tachycardia and atrial flutter, angina, and myocardial infarction.
摘要翻译： 公开了作为部分和全部A1腺苷受体激动剂的新型化合物，其可用于治疗各种疾病状态，特别是心动过速和心房扑动，心绞痛和心肌梗死。
-
公开(公告)号：US07304070B2
公开(公告)日：2007-12-04
申请号：US10942582
申请日：2004-09-16
申请人： Rao Kalla , Thao Perry , Elfatih Elzein , Vaibhav Varkhedkar , Xiaofen Li , Prabha Ibrahim , Venkata Palle , Dengming Xiao , Jeff Zablocki
发明人： Rao Kalla , Thao Perry , Elfatih Elzein , Vaibhav Varkhedkar , Xiaofen Li , Prabha Ibrahim , Venkata Palle , Dengming Xiao , Jeff Zablocki
IPC分类号： C07D473/06 , A61K31/522 , A61P25/28 , A61P11/06 , A61P25/16
CPC分类号： C07D473/00 , C07D473/06 , C07D473/08
摘要： Disclosed are novel A2B adenosine receptor antagonists having the structure of Formula I or Formula II: The compounds are particularly useful for treating asthma, inflammatory gastrointestinal tract disorders, cardiovascular diseases, neurological disorders, and diseases related to undesirable angiogenesis.
摘要翻译： 公开了具有式I或式II结构的新型A 2 B 2 N腺苷受体拮抗剂：
-
公开(公告)号：US20050038045A1
公开(公告)日：2005-02-17
申请号：US10947708
申请日：2004-09-23
申请人： Rao Kalla , Thao Perry , Elfatih Elzein , Vaibhav Varkhedkar , Xiaofen Li , Prabha Ibrahim , Venkata Palle , Dengming Xiao , Jeff Zablocki
发明人： Rao Kalla , Thao Perry , Elfatih Elzein , Vaibhav Varkhedkar , Xiaofen Li , Prabha Ibrahim , Venkata Palle , Dengming Xiao , Jeff Zablocki
IPC分类号： C07D473/04 , A61K31/522 , A61K31/53 , A61P1/12 , A61P3/10 , A61P9/00 , A61P9/10 , A61P11/06 , A61P25/16 , A61P25/28 , A61P27/02 , A61P35/00 , A61P43/00 , C07D285/08 , C07D473/00 , C07D473/06 , C07D473/08
CPC分类号： C07D473/00 , C07D473/06 , C07D473/08
摘要： Disclosed are novel compounds that are A2B adenosine receptor antagonists, useful for treating various disease states, including asthma and diarrhea.
摘要翻译： 公开了作为A2B腺苷受体拮抗剂的新型化合物，其可用于治疗各种疾病状态，包括哮喘和腹泻。
-
公开(公告)号：US20110130362A1
公开(公告)日：2011-06-02
申请号：US13016425
申请日：2011-01-28
申请人： Rao Kalla , Thao Perry , Elfatih Elzein , Vaibhav Varkhedkar , Xiaofen Li , Prabha Ibrahim , Venkata Palle , Dengming Xiao , Jeff Zablocki
发明人： Rao Kalla , Thao Perry , Elfatih Elzein , Vaibhav Varkhedkar , Xiaofen Li , Prabha Ibrahim , Venkata Palle , Dengming Xiao , Jeff Zablocki
IPC分类号： A61K31/522 , A61K31/695 , A61P11/06 , A61P3/10 , A61P35/04 , A61P1/00 , A61P25/00 , A61P25/28 , A61P25/16
CPC分类号： C07D473/06 , A61K31/522 , C07D473/04
摘要： Disclosed are novel compounds that are A2B adenosine receptor antagonists, useful for treating various disease states, including asthma and diarrhea.
-
公开(公告)号：US07939509B2
公开(公告)日：2011-05-10
申请号：US12724255
申请日：2010-03-15
申请人： Arvinder Dhalla , Elfatih Elzein , Prabha Ibrahim , Venkata Palle , Vaibhav Varkhedkar , Jeff Zablocki
发明人： Arvinder Dhalla , Elfatih Elzein , Prabha Ibrahim , Venkata Palle , Vaibhav Varkhedkar , Jeff Zablocki
CPC分类号： A61K31/52 , A61K31/7076
摘要： Disclosed are novel compounds a compound of Formula I that are partial and full A1 adenosine receptor agonists, useful for treating various disease states, in particular dyslipidemia, diabetes, decreased insulin sensitivity, Polycystic Ovarian Syndrome, Stein-Leventhal syndrome, and obesity.
摘要翻译： 公开了作为部分和全部A1腺苷受体激动剂的新颖化合物，其可用于治疗各种疾病状态，特别是血脂异常，糖尿病，胰岛素敏感性降低，多囊卵巢综合征，Stein-Leventhal综合征和肥胖症。
-
公开(公告)号：US20100222300A1
公开(公告)日：2010-09-02
申请号：US12776642
申请日：2010-05-10
申请人： Rao Kalla , Thao Perry , Elfatih Elzein , Vaibhav Varkhedkar , Xiaofen Li , Prabha Ibrahim , Venkata Palle , Dengming Xiao , Jeff Zablocki
发明人： Rao Kalla , Thao Perry , Elfatih Elzein , Vaibhav Varkhedkar , Xiaofen Li , Prabha Ibrahim , Venkata Palle , Dengming Xiao , Jeff Zablocki
IPC分类号： A61K31/695 , A61P35/00 , A61P3/10 , A61P11/06 , A61P9/00 , A61P1/12 , A61P25/00 , A61P25/28 , A61P25/16 , A61K31/52 , A61K31/522
CPC分类号： C07D473/06 , A61K31/522 , C07D473/04
摘要： Disclosed are novel compounds that are A2B adenosine receptor antagonists, useful for treating various disease states, including asthma and diarrhea.
摘要翻译： 公开了作为A2B腺苷受体拮抗剂的新型化合物，其可用于治疗各种疾病状态，包括哮喘和腹泻。
-
公开(公告)号：US20100210579A1
公开(公告)日：2010-08-19
申请号：US12724255
申请日：2010-03-15
申请人： Arvinder Dhalla , Elfatih Elzein , Prabha Ibrahim , Venkata Palle , Vaibhav Varkhedkar , Jeff Zablocki
发明人： Arvinder Dhalla , Elfatih Elzein , Prabha Ibrahim , Venkata Palle , Vaibhav Varkhedkar , Jeff Zablocki
CPC分类号： A61K31/52 , A61K31/7076
摘要： Disclosed are novel compounds a compound of Formula I that are partial and full A1 adenosine receptor agonists, useful for treating various disease states, in particular dyslipidemia, diabetes, decreased insulin sensitivity, Polycystic Ovarian Syndrome, Stein-Leventhal syndrome, and obesity.
摘要翻译： 公开了作为部分和全部A1腺苷受体激动剂的新颖化合物，其可用于治疗各种疾病状态，特别是血脂异常，糖尿病，胰岛素敏感性降低，多囊卵巢综合征，Stein-Leventhal综合征和肥胖症。
-
公开(公告)号：US20070185051A1
公开(公告)日：2007-08-09
申请号：US11641234
申请日：2006-12-18
申请人： Arvinder Dhalla , Elfatih Elzein , Prabha Ibrahim , Venkata Palle , Vaibhav Varkhedkar , Jeff Zablocki
发明人： Arvinder Dhalla , Elfatih Elzein , Prabha Ibrahim , Venkata Palle , Vaibhav Varkhedkar , Jeff Zablocki
IPC分类号： A61K31/7076
CPC分类号： A61K31/52 , A61K31/7076
摘要： Disclosed are novel compounds a compound of Formula I that are partial and full A1 adenosine receptor agonists, useful for treating various disease states, in particular dyslipidemia, diabetes, decreased insulin sensitivity, Polycystic Ovarian Syndrome, Stein-Leventhal syndrome, and obesity.
摘要翻译： 公开了作为部分和全部A 1 N 2腺苷受体激动剂的新颖化合物，其可用于治疗各种疾病状态，特别是血脂异常，糖尿病，胰岛素敏感性降低，多囊卵巢综合征，Stein- Leventhal综合征和肥胖症。
-
公开(公告)号：US20110257127A1
公开(公告)日：2011-10-20
申请号：US13169834
申请日：2011-06-27
申请人： Rao Kalla , Thao Perry , Elfatih Elzein , Vaibhav Varkhedkar , Xiaofen Li , Prabha Ibrahim , Venkata Palle , Dengming Xiao , Jeff Zablocki
发明人： Rao Kalla , Thao Perry , Elfatih Elzein , Vaibhav Varkhedkar , Xiaofen Li , Prabha Ibrahim , Venkata Palle , Dengming Xiao , Jeff Zablocki
IPC分类号： A61K31/695 , A61P11/06 , A61P35/00 , A61P9/10 , A61P25/00 , A61P25/28 , A61P25/16 , A61P3/10 , A61K31/522 , A61P1/00
CPC分类号： C07D473/06 , A61K31/522 , C07D473/04
摘要： Disclosed are novel compounds that are A2B adenosine receptor antagonists, useful for treating various disease states, including asthma and diarrhea.
摘要翻译： 公开了作为A2B腺苷受体拮抗剂的新型化合物，其可用于治疗各种疾病状态，包括哮喘和腹泻。
-
公开(公告)号：US07795269B2
公开(公告)日：2010-09-14
申请号：US11949229
申请日：2007-12-03
申请人： Rao Kalla , Thao Perry , Elfatih Elzein , Vaibhav Varkhedkar , Xiaofen Li , Prabha Ibrahim , Venkata Palle , Dengming Xiao , Jeff Zablocki
发明人： Rao Kalla , Thao Perry , Elfatih Elzein , Vaibhav Varkhedkar , Xiaofen Li , Prabha Ibrahim , Venkata Palle , Dengming Xiao , Jeff Zablocki
IPC分类号： A61K31/522 , C07D473/12 , C07D473/06 , C07D473/04 , A61P11/06 , A61P9/10 , A61P3/10
CPC分类号： C07D473/06 , A61K31/522 , C07D473/04
摘要： Disclosed are novel A2B adenosine receptor antagonists having the structure of Formula I or Formula II: The compounds are particularly useful for treating asthma, inflammatory gastrointestinal tract disorders, cardiovascular diseases, neurological disorders, and diseases related to undesirable angiogenesis.
-
-
-
-
-
-
-
-
-
搜索结果
177 条记录 (耗时 0.041 秒)
