利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

6 条记录 (耗时 0.04 秒)

    NOVEL PEPTIDES AND USES THEREOF
    3.
    发明申请
    NOVEL PEPTIDES AND USES THEREOF 审中-公开
    新颖的肽及其用途

    公开(公告)号：US20130331297A1

    公开(公告)日：2013-12-12

    申请号：US13810417

    申请日：2011-07-15

    申请人： Xiaomin Fan

    发明人： Xiaomin Fan

    IPC分类号： C12N15/10

    CPC分类号： C12N15/1037 ,  C07K16/3069 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/52 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/92 ,  C40B40/02

    摘要： The present disclosure relates to novel peptides and their uses including, proline-rich peptides that are useful for displaying a protein of interest at the surfaces of a host cell such as a yeast. Polynucleotides, proteins, vectors and host cells that comprise or encode the novel proline-rich peptides, including libraries comprising such polynucleotides, proteins, vectors and/or host cells that comprise or encode novel proline-rich peptides are provided. Methods and materials for display and expression of proteins of interest are provided. Methods and materials are also provided by the present disclosure for isolating peptides capable of displaying a protein of interest (e.g., a marker protein), for generating libraries to display and/or express proteins of interest (e.g., antibodies such as humanized antibodies), for generating secretion vectors for such proteins of interest, and for generating proteins of interest (e.g., antibodies).

    摘要翻译： 本公开涉及新型肽及其用途，包括可用于在宿主细胞如酵母表面显示感兴趣的蛋白质的富含脯氨酸的肽。 提供了包含或编码新的富含脯氨酸肽的多核苷酸，蛋白质，载体和宿主细胞，包括包含这种多核苷酸的蛋白质，蛋白质，载体和/或宿主细胞，其包含或编码新的富含脯氨酸的肽。 提供了用于显示和表达目的蛋白质的方法和材料。 本发明还提供方法和材料，用于分离能够显示感兴趣的蛋白质的肽（例如，标记蛋白），用于产生用于显示和/或表达目的蛋白质的文库（例如抗体，例如人源化抗体）， 用于产生感兴趣的蛋白质的分泌载体，以及产生目的蛋白质（例如，抗体）。

    Methods for the identification and the isolation of epitope specific antibodies
    4.
    发明申请
    Methods for the identification and the isolation of epitope specific antibodies 审中-公开
    识别和分离表位特异性抗体的方法

    公开(公告)号：US20080003617A1

    公开(公告)日：2008-01-03

    申请号：US11804489

    申请日：2007-05-18

    申请人： Xiaomin Fan ,  Xiaoming Chen

    发明人： Xiaomin Fan ,  Xiaoming Chen

    IPC分类号： C07K16/00 ,  G01N33/53

    CPC分类号： C07K16/00 ,  C07K16/005 ,  C07K16/36 ,  C07K2317/21 ,  C07K2317/24 ,  G01N33/6854

    摘要： The present invention relates to methods for the identification of an antibody that is specific to an epitope of interest. In certain preferred embodiments, methods of the invention comprise an enrichment procedure and/or a subtractive selection that facilitates the rapid identification of an epitope specific antibody. Methods of the invention also facilitate the identification of an antibody derived from a desired species that is specific for the epitope recognized by another antibody derived from a different species. Methods of the invention further facilitate the identification of an antibody specific to an epitope found in two different antigens, and an antibody capable of binding an epitope of interest but not a homologue of the epitope. Methods of the invention also facilitate the identification of an antibody specific for an antigen presented in one sample, but not, or significantly less, in another sample.

    摘要翻译： 本发明涉及用于鉴定对感兴趣的表位特异性的抗体的方法。 在某些优选的实施方案中，本发明的方法包括促进快速鉴定表位特异性抗体的富集方法和/或减法选择。 本发明的方法还有助于鉴定衍生自对来自不同物种的另一抗体识别的表位特异性的所需物种的抗体。 本发明的方法进一步有助于鉴定在两种不同抗原中发现的表位的特异性抗体，以及能够结合感兴趣的表位而不是表位的同系物的抗体。 本发明的方法还有助于鉴定在一个样品中呈递的抗原特异的抗体，但是在另一个样品中鉴定不是或显着更少。

    Portable power bank
    5.
    外观设计
    Portable power bank 有权

    公开(公告)号：USD1003829S1

    公开(公告)日：2023-11-07

    申请号：US29878603

    申请日：2023-06-26

    申请人： Xiaomin Fan

    设计人： Xiaomin Fan

    摘要： FIG. 1 is a front, left, and bottom view of a portable power bank, showing my new design;
    FIG. 2 is a rear, right, and top perspective view thereof;
    FIG. 3 is a front view thereof;
    FIG. 4 is a rear view thereof;
    FIG. 5 is a top plan view thereof;
    FIG. 6 is a bottom plan view thereof;
    FIG. 7 is a left side elevation view thereof;
    FIG. 8 is a right side elevation view thereof; and,
    FIG. 9 is a front, left, and bottom perspective view of the portable power bank of FIG. 1 in a state of use.
    The broken lines depict portions of the portable power bank in which the design is embodied that form no part of the claimed design.