摘要:
An afterburner flameholder for a gas turbine engine having a central diffuser cone, a generally cylindrical outer shell and fuel spray bars between the shell and cone defining an afterburner region is provided, which comprise an annular member with an asymmetric V-shaped cross section. The annular member is adapted to be secured to the engine in the afterburner region with the apex of the V facing upstream in the axial direction toward the fuel spray bars. The annular member has a first and second circular sidewall member each joined at one end forming an apex, the annular member in cross section has unequal length sidewall members. The difference in length between the distal ends of the first and second circular sidewall members is sufficient to cause spanwise vortices shed at the distal ends of the sidewall members to be out of phase when they meet downstream from the flameholder. The different lengths of the distal ends of the sidewall members results in one sidewall member extending further from the apex than the other, situating the distal ends in different planes so that spanwise vortices shed from the asymmetric sidewall members travel different path lengths and are out of phase when they meet downstream.
摘要:
A V-shaped afterburner flameholder for a gas turbine engine has a plurality of rectangular tabs coextensive with and lying in the planes of the flameholder sidewalls. The tabs on opposing sidewalls alternate so as to introduce streamwise and spanwise (transverse) vortices in the flowing gas. The resultant streamwise vortices tend to reduce resonating vortex oscillations (screech) and the need for an acoustic liner to suppress such screech.
摘要:
Methods of imaging tumors are disclosed. The methods utilize an endothelin ETB receptor agonist or an endothelin ETA receptor antagonist, in combination with an imaging agent, to detect a tumor in mammals, including humans.
摘要:
Composition and methods of treating pain and reducing or reversing tolerance to opiate analgesics are disclosed. The composition and method utilize an opiate analgesic and an endothelin antagonist as active agents to treat pain in mammals, including humans.
摘要:
Methods, compositions and articles of manufacture for contributing to the treatment of cancers, including solid tumors, are disclosed. The methods, compositions and articles of manufacture can utilize an endothelin B agonist (ETB) to enhance the delivery and resulting efficacy of a chemotherapeutic agent.
摘要:
A burner (27) of a gas turbine engine (10) includes a cylindrical basket (60) comprising an air flow reversal region (86). The flow reversal region ends at an air inlet plane (84) of the basket. The burner also includes a flow conditioner (90) disposed in the flow reversal region transecting an air flow (80) flowing non-uniformly through the flow reversal region, the flow conditioner being effective to mitigate variation of the air flow entering the basket across the inlet plane.
摘要:
Methods, compositions and articles of manufacture for contributing to the treatment of a solid cancerous tumor are disclosed. The methods, compositions and articles of manufacture can utilize an endothelin B agonist (ETB) to enhance the delivery of a chemotherapeutic agent to a solid tumor in mammals, including humans.
摘要翻译:公开了有助于治疗固体癌性肿瘤的方法,组合物和制品。 方法,组合物和制品可以利用内皮素B激动剂(ET B B)来增强哺乳动物(包括人)中化疗剂对实体瘤的递送。
摘要:
Combustion-induced instabilities are minimized in gas turbine combustors by incorporating one or more Helmholtz resonators into the combustor. First and second plates located in the head end of the combustor casing define one cavity, and a sleeve located between the casing and the liner defines another cavity. Each of the two cavities is connected to the combustion chamber by one or more throats, thus forming Helmholtz resonators. The throats of each resonator can be tubes of different lengths and/or different cross-sectional areas to provide dynamics suppression over a broad band of frequencies. The throats can also be arranged such that each throat is associated with a different portion of its respective cavity, each cavity portion having a different volume.
摘要:
Composition and methods of treating pain and reducing or reversing tolerance to opiate analgesics are disclosed. The composition and method utilize an opiate analgesic and an endothelin antagonist as active agents to treat pain in mammals, including humans.
摘要:
The present invention relates to compositions and methods for managing opioid tolerance and reducing opioid withdrawal. More specifically, the present invention provides for endothelin, endothelin receptors, and endothelin receptor antagonists and agonists as a means for managing G-protein activity in the context of opioid tolerance and withdrawal.