公开(公告)号：US20240316120A1

公开(公告)日：2024-09-26

申请号：US18628884

申请日：2024-04-08

申请人： The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization

发明人： Itzhak MIZRAHI ,  Elie JAMI

IPC分类号： A61K35/74 ,  A23K10/18 ,  A23K20/195 ,  A23K50/10 ,  A23K50/60 ,  A61K35/66 ,  C12N1/20 ,  C12Q1/6869 ,  C12Q1/689

CPC分类号： A61K35/74 ,  A23K10/18 ,  A23K20/195 ,  A23K50/10 ,  A23K50/60 ,  A61K35/66 ,  C12N1/20 ,  C12Q1/6869 ,  C12Q1/689 ,  C12Q2600/124

摘要： A method of mimicking a phenotype of a first ruminating animal in a second ruminating animal is disclosed. The method comprises administering to the second ruminating animal a microbial composition comprising a plurality of microbes having a signature which is statistically significantly similar to the microbial signature of a rumen microbiome of the first ruminating animal, wherein the first and the second ruminating animal are of identical species, thereby mimicking the phenotype of the first ruminating animal in the second ruminating animal.

公开(公告)号：US20240284937A1

公开(公告)日：2024-08-29

申请号：US18634899

申请日：2024-04-13

申请人： ANIPHA TECHNOLOGIES PTY LTD

发明人： Xianfeng Peng ,  Huacheng Huang

IPC分类号： A23K20/142 ,  A23K50/30 ,  A23K50/60 ,  A23K50/75 ,  A23K50/80 ,  A61K31/197 ,  C07C229/24 ,  C07C237/12 ,  C07C275/16

CPC分类号： A23K20/142 ,  A23K50/30 ,  A23K50/60 ,  A23K50/75 ,  A23K50/80 ,  A61K31/197 ,  C07C229/24 ,  C07C237/12 ,  C07C275/16

摘要： Disclosed herein is use of an aspartic acid derivative having a structure represented by formula (I), or a racemate, stereoisomer, geometric isomer, tautomer, solvate or feed-acceptable salt thereof, in preparing an animal feed additive that significantly improves production performance of farmed animals,




wherein each of Y and X is independently a C1-C20 alkyl or H; R1 is R1aC(═O) or H; R2 is R2aC(═O); and each of R1a and R2a is independently (A)(B)N—(CH2)0-5—, and each of A and B is independently a C1-C20 alkyl or H.

公开(公告)号：US20240218420A1

公开(公告)日：2024-07-04

申请号：US18613181

申请日：2024-03-22

申请人： The State of Israel, Ministry of Agriculture & Rural Development, Agriculture Research Organization

发明人： Itzhak MIZRAHI

IPC分类号： C12Q1/06 ,  A23K10/18 ,  A23K50/10 ,  A23K50/60 ,  A61K9/00 ,  A61K35/00 ,  A61K35/741 ,  A61K35/744 ,  A61K45/06 ,  C12Q1/689

CPC分类号： C12Q1/06 ,  A23K10/18 ,  A23K50/10 ,  A23K50/60 ,  A61K9/0031 ,  A61K9/0056 ,  A61K35/741 ,  A61K35/744 ,  A61K45/06 ,  C12Q1/689 ,  A61K2035/115

摘要： A method of determining the feed efficiency and methane production of a ruminating animal comprising analyzing the number and/or diversity of a bacterial taxon of a microbiome of the animal or of a gene content of said microbiome, wherein a number and/or diversity of said taxon below a predetermined level is indicative of an animal having a high feed efficiency and low methane production, or a number of genes below a predetermined level is indicative of an animal having a high feed efficiency and low methane production.

公开(公告)号：US20230181503A1

公开(公告)日：2023-06-15

申请号：US17915007

申请日：2021-03-30

申请人： LUCTA, S.A.

发明人： Jose Javier Pastor Porras ,  Maria Gema Tedo Perez ,  Marta Blanch Saborit ,  Jose Sola Parera

IPC分类号： A61K31/192 ,  A61P1/00 ,  A61K31/05 ,  A23K20/105 ,  A23K20/111 ,  A23K20/158 ,  A23K50/30 ,  A23K50/60 ,  A23K50/75

CPC分类号： A61K31/192 ,  A61P1/00 ,  A61K31/05 ,  A23K20/105 ,  A23K20/111 ,  A23K20/158 ,  A23K50/30 ,  A23K50/60 ,  A23K50/75

摘要： Present invention relates to the use of hydroxytyrosol (HT), maslinic acid (MA) and oleanolic acid (OA) as additive in feed for a domesticated animal at very early days of life or from birth. The invention provides an additive with particular amounts of these three ingredients and an additivated feedstuff ready to use comprising said additive.

公开(公告)号：US20190216094A1

公开(公告)日：2019-07-18

申请号：US16312762

申请日：2017-06-30

申请人： Fermentationexperts A/S

发明人： Jens Høffner Legarth

IPC分类号： A01N65/08 ,  A01N65/20 ,  A61K36/48 ,  A61K36/31 ,  A23L33/105 ,  A23K10/12 ,  A23K10/30 ,  A23K10/20 ,  A23L13/40 ,  A23K50/30 ,  A23K50/60

CPC分类号： A01N65/08 ,  A01N65/20 ,  A01N65/34 ,  A23K10/12 ,  A23K10/20 ,  A23K10/30 ,  A23K50/30 ,  A23K50/60 ,  A23L13/45 ,  A23L33/105 ,  A23V2002/00 ,  A61K36/31 ,  A61K36/48

摘要： The present invention relates to the use of a composition comprising a plant material obtained from the Brassicaceae family and/or the Fabaceae family for inhibiting or reducing growth of a fungus organism.

公开(公告)号：US20180326020A1

公开(公告)日：2018-11-15

申请号：US16042841

申请日：2018-07-23

申请人： ELANCO US INC.

发明人： David M. ANDERSON ,  Sergey PODKOVYROV ,  Yuefang HUANG ,  Kurt SCHUSTER ,  Jon Edward FERREL

IPC分类号： A61K38/46 ,  A23K20/189 ,  C12N9/16 ,  A23K50/60 ,  A23K50/30 ,  A23K50/75

CPC分类号： A61K38/465 ,  A23K20/189 ,  A23K50/30 ,  A23K50/60 ,  A23K50/75 ,  A23V2002/00 ,  C12N9/16 ,  C12Y301/03001 ,  A23V2200/32

摘要： Methods for reducing the environmental impact of animal waste are described. In particular embodiments, the methods comprise administering to an animal an enzyme, such as alkaline phosphatase, that is effective to reduce the amount of a detrimental compound, such as ammonia or phosphorous, that is present in or released from animal waste. Also provided is a method for increasing phosphorus digestion in an animal. Compositions suitable for use in such methods are also described.

公开(公告)号：US10006073B2

公开(公告)日：2018-06-26

申请号：US14248914

申请日：2014-04-09

申请人： Chr. Hansen A/S

发明人： Beatrice Nielsen ,  Tina Styrishave ,  Mette Dines Cantor ,  Patrick Derkx ,  Jonna Nielsen ,  Robert Lantz

IPC分类号： C12Q1/02 ,  A23K10/18 ,  A23K20/163 ,  A23K50/75 ,  A23K50/30 ,  A23K50/60

CPC分类号： C12Q1/02 ,  A23K10/18 ,  A23K20/163 ,  A23K50/30 ,  A23K50/60 ,  A23K50/75 ,  G01N2333/32

摘要： Methods are provided for assaying whether a Bacillus composition comprising at least one Bacillus strain is capable of increasing the amount of sugar available from animal feed comprising non-starch polysaccharides (NSP) in vivo when the Bacillus composition and animal feed are fed to an animal. Methods also are provided for increasing the amount of sugar available from animal feed comprising non-starch polysaccharides (NSP) when the animal feed is fed to an animal, comprising adding to the animal feed a Bacillus composition comprising at least one Bacillus strain, wherein the composition produces 120 hexose equivalents (μmol/ml) or more when measured by the method described herein. Animal feeds comprising 14% (w/w) or more of non-starch polysaccharides (NSP) if the animal feed is for a piglet, lactating sow, broiler or layer, or 19% (w/w) or more of non-starch polysaccharides (NSP) if the animal feed is for a grower-finisher pig or gestating sow, and a Bacillus composition comprising at least one Bacillus strain, as well as methods and uses relating thereto, also are provided.

公开(公告)号：US20180146697A1

公开(公告)日：2018-05-31

申请号：US15365442

申请日：2016-11-30

申请人： PURINA ANIMAL NUTRITION LLC

发明人： Bill L. Miller

IPC分类号： A23K20/10 ,  A23K50/30 ,  A23C11/02

CPC分类号： A23K20/10 ,  A23C11/02 ,  A23C2240/15 ,  A23K20/121 ,  A23K50/30 ,  A23K50/60 ,  A23V2002/00 ,  A23V2250/2116 ,  A23V2250/21172

摘要： Isoflavone-supplemented milk replacers fed to young animals during a pre-weaning provides isoflavones in the milk replacer at a level of about 700 mg per kilogram of the milk replacer, and/or provides about 450 mg of the supplemental isoflavone in at least about 1.5 pounds of the milk replacer by dry weight such that the animal ingests this amount of the isoflavone per day, and/or provides in the milk replacer at least about 50 mg of isoflavone per pound of the animal's birth weight is ingested per day. In response to ingesting the isoflavone-supplemented milk replacer, the young animal experiences improved performance.

公开(公告)号：US09975914B2

公开(公告)日：2018-05-22

申请号：US15234937

申请日：2016-08-11

申请人： Akeso Biomedical, Inc.

发明人： Dlawer Ala'Aldeen ,  Jafar Mahdavi ,  Panos Soultanas

IPC分类号： A61K31/295 ,  C07F15/02 ,  A61K45/06 ,  A61K31/7036 ,  G02B1/04 ,  C09D5/14 ,  A23K20/195 ,  A23K20/20 ,  A23K50/10 ,  A23K50/30 ,  A23K50/60 ,  A23K50/75 ,  A23L33/10 ,  A23L33/16 ,  A01N37/44 ,  A61K31/197 ,  A61K31/198 ,  A01N59/16 ,  A61L2/16

CPC分类号： C07F15/025 ,  A01N37/10 ,  A01N37/36 ,  A01N37/44 ,  A01N59/16 ,  A23K20/195 ,  A23K20/30 ,  A23K50/10 ,  A23K50/30 ,  A23K50/60 ,  A23K50/75 ,  A23L33/127 ,  A23L33/16 ,  A23V2002/00 ,  A61K31/197 ,  A61K31/198 ,  A61K31/295 ,  A61K31/7036 ,  A61K45/06 ,  A61L2/0088 ,  A61L2/16 ,  A61L2/18 ,  A61L2/22 ,  A61L12/08 ,  A61L2202/24 ,  C09D5/14 ,  G02B1/043

摘要： A method of enhancing the growth of an animal is provided. The method includes causing the animal to ingest or absorb an effective amount of a preparation obtainable by a process including, bringing a tyrosinate moiety into contact with an Fe(III)-containing substance, optionally wherein the tyrosinate moiety is tyrosine and it is brought into contact with the Fe(III)-containing substance in the presence of a base, or wherein the tyrosinate moiety is a tyrosine salt and it is brought into contact with an Fe(III)-containing substance. Methods for inhibiting, reducing, or preventing biofilm formation or buildup on a surface; the treatment of, inhibition of growth of, and inhibition of colonization by, bacteria, both in biological and non-biological environments; disinfecting surfaces, potentiating the effects of antibiotics and other anti-microbial agents, and increasing the sensitivity of bacteria and other microorganisms, to anti-microbial agents are also provided.

公开(公告)号：US20180078589A1

公开(公告)日：2018-03-22

申请号：US15558110

申请日：2016-03-11

申请人： Evolve BioSystems, Inc.

发明人： David KYLE ,  David MILLS ,  Carlito LEBRILLA ,  Samara FREEMAN-SHARKEY ,  Steven FRESE

IPC分类号： A61K35/744 ,  A61K35/745 ,  A61K35/747

CPC分类号： A61K35/744 ,  A23K10/18 ,  A23K50/20 ,  A23K50/30 ,  A23K50/60 ,  A23L33/125 ,  A23L33/135 ,  A23L33/21 ,  A23L33/40 ,  A61K9/1623 ,  A61K9/1635 ,  A61K9/19 ,  A61K31/7004 ,  A61K31/7012 ,  A61K35/74 ,  A61K35/745 ,  A61K35/747 ,  A61K2300/00

摘要： Compositions comprising at least two non-pathogenic microbes are described herein. The non-pathogenic microbes may be from a first species capable of internalizing and/or metabolizing dietary glycans and/or from a second species capable of consuming and metabolizing free sugar monomers. Methods of making and use in treating and/or preventing the overgrowth of pathogenic bacteria in mammals are also described herein.