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1.发明申请公开(公告)号：US20190323086A1
公开(公告)日：2019-10-24
申请号：US16393322
申请日：2019-04-24
申请人： Eric Leuthardt , Gavin Dunn , Hong Chen , Allegra Petti
发明人： Eric Leuthardt , Gavin Dunn , Hong Chen , Allegra Petti
IPC分类号： C12Q1/6886 , A61B10/00 , A61N7/00 , A61B5/055 , A61B5/00 , A61B90/11 , C12Q1/6851
摘要： Among the various aspects of the present disclosure is the provision of a noninvasive and localized brain liquid biopsy using focused ultrasound. Briefly, therefore, the present disclosure is directed to methods and systems to identify brain lesion or tumor characteristics without the need for a solid brain biopsy.
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公开(公告)号：US11696926B2
公开(公告)日：2023-07-11
申请号：US16774425
申请日：2020-01-28
IPC分类号： A61K35/14 , A61P35/02 , C12N5/0783 , A61K38/21
CPC分类号： A61K35/14 , A61K38/217 , A61P35/02 , C12N5/0636
摘要： Among the various aspects of the present disclosure is the provision of methods and compositions for upregulating MHC class II in cancer cells (e.g., a hematological cancer cell). Also provided are methods of treatment for subjects suffering from hematological cancers, comprising administration of interferon-γ (IFN-γ). The methods of treatment provided herein may be particularly suitable for subjects who have received an allogenic transplant or have suffered a relapse.
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公开(公告)号：US20200237817A1
公开(公告)日：2020-07-30
申请号：US16774425
申请日：2020-01-28
IPC分类号： A61K35/14 , A61K38/21 , C12N5/0783 , A61P35/02
摘要： Among the various aspects of the present disclosure is the provision of methods and compositions for upregulating MHC class II in cancer cells (e.g., a hematological cancer cell). Also provided are methods of treatment for subjects suffering from hematological cancers, comprising administration of interferon-γ (IFN-γ). The methods of treatment provided herein may be particularly suitable for subjects who have received an allogenic transplant or have suffered a relapse.
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