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公开(公告)号：US07263401B2
公开(公告)日：2007-08-28
申请号：US10835233
申请日：2004-04-29
摘要： An implantable medical device (IMD) including a nonhermetic battery is described. The IMD includes components and a power source module that includes the nonhermetic battery. The IMD also includes a barrier to substantially impede movement of substances from the nonhermetic battery to the components. The barrier may include a hermetic feedthrough, a gel, a polymer, or a solid electrolyte within the nonhermetic battery, and a seal member. The barrier may also be a material that encapsulates the nonhermetic battery and a getter within the IMD. In some embodiments, the IMD comprises a modular IMD including an interconnect member. In that case, the barrier may include a material that fills at least a portion of a void defined by the interconnect member. A length and a cross-sectional area of the interconnect member may also act as a barrier.
摘要翻译： 描述了包括非密封电池的可植入医疗装置（IMD）。 IMD包括组件和包含非密封电池的电源模块。 IMD还包括阻止物质从非密封电池移动到部件的屏障。 阻挡层可以包括非密封电池内的密封馈通，凝胶，聚合物或固体电解质，以及密封构件。 屏障还可以是在IMD内封装非密封电池和吸气剂的材料。 在一些实施例中，IMD包括包括互连构件的模块化IMD。 在这种情况下，阻挡层可以包括填充由互连构件限定的空隙的至少一部分的材料。 互连构件的长度和横截面积也可以用作屏障。
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公开(公告)号：US07881796B2
公开(公告)日：2011-02-01
申请号：US11831333
申请日：2007-07-31
IPC分类号： A61N1/08
摘要： An implantable medical device (IMD) including a nonhermetic battery is described. The IMD includes components and a power source module that includes the nonhermetic battery. The IMD also includes a barrier to substantially impede movement of substances from the nonhermetic battery to the components. The barrier may include a hermetic feedthrough, a gel, a polymer, or a solid electrolyte within the nonhermetic battery, and a seal member. The barrier may also be a material that encapsulates the nonhermetic battery and a getter within the IMD. In some embodiments, the IMD comprises a modular IMD including an interconnect member. In that case, the barrier may include a material that fills at least a portion of a void defined by the interconnect member. A length and a cross-sectional area of the interconnect member may also act as a barrier.
摘要翻译： 描述了包括非密封电池的可植入医疗装置（IMD）。 IMD包括组件和包含非密封电池的电源模块。 IMD还包括阻止物质从非密封电池移动到部件的屏障。 阻挡层可以包括非密封电池内的密封馈通，凝胶，聚合物或固体电解质，以及密封构件。 屏障还可以是在IMD内封装非密封电池和吸气剂的材料。 在一些实施例中，IMD包括包括互连构件的模块化IMD。 在这种情况下，阻挡层可以包括填充由互连构件限定的空隙的至少一部分的材料。 互连构件的长度和横截面积也可以用作屏障。
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3.发明授权Variable recharge determination for an implantable medical device and method therefore 有权因此，可植入式医疗装置的可变补充确定和方法公开(公告)号：US07616995B2
公开(公告)日：2009-11-10
申请号：US11414156
申请日：2006-04-28
IPC分类号： A61N1/378
CPC分类号： A61N1/3787
摘要： Implantable medical device adapted to provide a therapeutic output to a patient. A therapy module, operatively coupled to a battery, is adapted to provide the therapeutic output. A control circuit provides an action indicative of recharging the battery when the voltage of the battery reaches a recharge voltage wherein the recharge voltage is varied as the battery ages. Also a method of providing a therapeutic output to a patient using an implantable medical device having a battery having a voltage. An action indicative of recharging the battery is provided when the voltage of the battery reaches a recharge voltage. The recharge voltage is varied as the battery ages.
摘要翻译： 适于向患者提供治疗输出的可植入医疗装置。 可操作地耦合到电池的治疗模块适于提供治疗输出。 当电池的电压达到再充电电压时，控制电路提供指示对电池再充电的动作，其中充电电压随电池老化而变化。 还有一种使用具有电压的电池的可植入医疗装置向患者提供治疗输出的方法。 当电池的电压达到充电电压时，提供指示对电池再充电的动作。 充电电压随电池老化而变化。
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公开(公告)号：US07596408B2
公开(公告)日：2009-09-29
申请号：US10837319
申请日：2004-04-30
申请人： Ruchika Singhal , Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Paulette C. Olson , Erik R. Scott , James E. Randall
发明人： Ruchika Singhal , Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Paulette C. Olson , Erik R. Scott , James E. Randall
IPC分类号： A61N1/02
CPC分类号： A61N1/3754 , A61B5/076 , A61B2560/04 , A61L31/16 , A61L2300/404 , A61N1/3605 , A61N1/375
摘要： An implantable medical device with anti-infection agent. The implantable medical device may be configured for placement in the head of a patient and for monitoring or treatment of the brain. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the adjacent tissue. The anti-infection agent may be provided on or impregnated in the housing or the member. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled to provide a smaller profile. In some embodiments the implantable medical device may include both anti-infection and lubricious materials.
摘要翻译： 具有抗感染剂的可植入医疗器械。 可植入医疗装置可被配置用于放置在患者的头部并用于监测或治疗大脑。 可植入医疗装置可以具有壳体，或者其可以具有壳体和用于在装置和相邻组织之间提供平滑界面的构件。 抗感染剂可以设置在或浸渍在壳体或构件中。 在一些实施例中，设备包括单个模块，而在其它实施例中，多个模块被耦合以提供较小的轮廓。 在一些实施例中，可植入医疗装置可以包括抗感染和光滑材料。
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公开(公告)号：US20090292327A1
公开(公告)日：2009-11-26
申请号：US12536258
申请日：2009-08-05
申请人： Ruchika Singhal , Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Paulette C. Olson , Erik R. Scott , James E. Randall
发明人： Ruchika Singhal , Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Paulette C. Olson , Erik R. Scott , James E. Randall
IPC分类号： A61N1/02
CPC分类号： A61N1/3754 , A61B5/076 , A61B2560/04 , A61L31/16 , A61L2300/404 , A61N1/3605 , A61N1/375
摘要： An implantable medical device comprises an anti-infection agent. The implantable medical device may be configured for placement in the head of a patient and for monitoring or treatment of the brain. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the adjacent tissue. The anti-infection agent may be provided on or impregnated in the housing or the member. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled to provide a smaller profile. In some embodiments the implantable medical device may include both anti-infection and lubricious materials.
摘要翻译： 可植入医疗装置包括抗感染剂。 可植入医疗装置可被配置用于放置在患者的头部并用于监测或治疗大脑。 可植入医疗装置可以具有壳体，或者其可以具有壳体和用于在装置和相邻组织之间提供平滑界面的构件。 抗感染剂可以设置在或浸渍在壳体或构件中。 在一些实施例中，设备包括单个模块，而在其它实施例中，多个模块被耦合以提供较小的轮廓。 在一些实施例中，可植入医疗装置可以包括抗感染和光滑材料。
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公开(公告)号：US09162072B2
公开(公告)日：2015-10-20
申请号：US11526514
申请日：2006-09-25
申请人： Ruchika Singhal , Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Paulette C. Olson , Erik R. Scott , James E. Randall
发明人： Ruchika Singhal , Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Paulette C. Olson , Erik R. Scott , James E. Randall
CPC分类号： A61N1/375 , A61B2560/0443 , A61N1/0526 , A61N1/3605
摘要： An implantable medical device with lubricious material permits implantable medical devices to have a reduced friction between the device and at least a portion of the surrounding tissue. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the tissue. The lubricious material may be provided on or impregnated in the housing or the member. In some embodiments, the device is configured for implantation in the head of a human body. In other embodiments, the device is configured for implantation between the cranium and the scalp. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled together to provide a smaller profile.
摘要翻译： 具有润滑材料的可植入医疗装置允许植入式医疗装置在装置与周围组织的至少一部分之间具有减小的摩擦。 可植入医疗装置可以具有壳体，或者可以具有壳体和用于在装置和组织之间提供平滑界面的构件。 润滑材料可以设置在或浸渍在壳体或构件中。 在一些实施例中，该装置被配置用于植入人体的头部。 在其他实施例中，该装置被配置用于在颅骨和头皮之间植入。 在一些实施例中，设备包括单个模块，而在其他实施例中，多个模块耦合在一起以提供较小的轮廓。
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公开(公告)号：US08086313B2
公开(公告)日：2011-12-27
申请号：US12536258
申请日：2009-08-05
申请人： Ruchika Singhal , Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Paulette C. Olson , Erik R. Scott , James E. Randall
发明人： Ruchika Singhal , Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Paulette C. Olson , Erik R. Scott , James E. Randall
IPC分类号： A61N1/02
CPC分类号： A61N1/3754 , A61B5/076 , A61B2560/04 , A61L31/16 , A61L2300/404 , A61N1/3605 , A61N1/375
摘要： An implantable medical device comprises an anti-infection agent. The implantable medical device may be configured for placement in the head of a patient and for monitoring or treatment of the brain. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the adjacent tissue. The anti-infection agent may be provided on or impregnated in the housing or the member. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled to provide a smaller profile. In some embodiments the implantable medical device may include both anti-infection and lubricious materials.
摘要翻译： 可植入医疗装置包括抗感染剂。 可植入医疗装置可被配置用于放置在患者的头部并用于监测或治疗大脑。 可植入医疗装置可以具有壳体，或者其可以具有壳体和用于在装置和相邻组织之间提供平滑界面的构件。 抗感染剂可以设置在或浸渍在壳体或构件中。 在一些实施例中，设备包括单个模块，而在其它实施例中，多个模块被耦合以提供较小的轮廓。 在一些实施例中，可植入医疗装置可以包括抗感染和光滑材料。
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公开(公告)号：US07529586B2
公开(公告)日：2009-05-05
申请号：US10731867
申请日：2003-12-09
申请人： Carl D. Wahlstrand , Darren A. Janzig , Ruchika Singhal , Robert M. Skime , Erik R. Scott , James E. Randall
发明人： Carl D. Wahlstrand , Darren A. Janzig , Ruchika Singhal , Robert M. Skime , Erik R. Scott , James E. Randall
IPC分类号： A61N1/36
CPC分类号： A61N1/375 , A61N1/3605 , A61N1/3754 , A61N1/3758
摘要： At least one surface of an implantable medical device is concave along at least one axis such that it substantially conforms to a surface within a patient, such as the cranium, when it is implanted on that surface. In some embodiments, the surface of the implantable medical device substantially conforms to an arc with a radius that is between 4.5 and 9.5 centimeters, and is preferably approximately equal to 7 centimeters. In some embodiments, the implantable medical device comprises a plurality of interconnected modules, and an overmold that at least partially encapsulates each of the modules. In such embodiments, at least one surface of the overmold is concave along at least one axis. Further, each of the modules of such an implantable medical device may comprise a housing, and at least one surface of at least one of the housings may be concave along at least one axis.
摘要翻译： 可植入医疗装置的至少一个表面沿着至少一个轴线是凹形的，使得当植入在该表面上时，其基本上符合患者（例如颅骨）内的表面。 在一些实施例中，可植入医疗装置的表面基本上符合半径在4.5和9.5厘米之间的弧度，并且优选地大约等于7厘米。 在一些实施例中，可植入医疗装置包括多个互连的模块，以及至少部分地封装每个模块的包覆模制。 在这样的实施例中，包覆模制体的至少一个表面沿着至少一个轴线是凹形的。 此外，这种可植入医疗装置的每个模块可以包括壳体，并且至少一个壳体的至少一个表面沿着至少一个轴线可以是凹形的。
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公开(公告)号：US08620453B2
公开(公告)日：2013-12-31
申请号：US12954563
申请日：2010-11-24
IPC分类号： A61N1/05
CPC分类号： A61N1/08 , A61N1/05 , A61N1/0534 , A61N1/0551 , A61N1/086 , A61N1/36071
摘要： A medical lead is provided for use in a pulse stimulation system of the type which includes a pulse generator for producing electrical stimulation therapy. The lead comprises an elongate insulating body and at least one electrical conductor within the insulating body. The conductor has a proximal end configured to be electrically coupled to the pulse generator and has a DC resistance in the range of 375-2000 ohms. At least one distal electrode is coupled to the conductor.
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公开(公告)号：US08457744B2
公开(公告)日：2013-06-04
申请号：US10730877
申请日：2003-12-09
IPC分类号： A61N1/08
CPC分类号： A61N1/375 , A61N1/3605 , A61N1/3754 , A61N1/3758
摘要： Components of an implantable medical device are arranged to facilitate a low-profile housing. A circuit board within the housing carries integrated circuits and discrete components. In some embodiments, the integrated circuits and discrete components are located on first and second opposing surfaces of the circuit board, respectively. In some embodiments, the implantable medical device is implanted on a cranium of a patient and the housing is concave such that it substantially conforms to the cranium. In such embodiments, the integrated circuits and/or discrete components can be arranged on the circuit board according to height to better conform to the concavity of the housing. In some embodiments, the implantable medical device includes a telemetry coil that is positioned within the housing such that it occupies space that cannot be practically occupied by the circuit board.
摘要翻译： 可植入医疗装置的部件被布置成便于小型外壳。 外壳内的电路板承载集成电路和分立元件。 在一些实施例中，集成电路和分立元件分别位于电路板的第一和第二相对表面上。 在一些实施例中，将可植入医疗装置植入患者的颅骨上，并且所述外壳是凹形的，使得其基本上符合颅骨。 在这样的实施例中，集成电路和/或分立组件可以根据高度布置在电路板上，以更好地符合壳体的凹面。 在一些实施例中，可植入医疗装置包括位于壳体内的遥测线圈，使其占据不能被电路板实际占据的空间。
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