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公开(公告)号：US09949823B2
公开(公告)日：2018-04-24
申请号：US14704006
申请日：2015-05-05
Applicant: Ethicon, Inc.
Inventor： Krasimira Hristov , Gaoyuan Gavin Chen , Mark T. Mooney , James A. Matrunich , Jianxin Guo , Emil Richard Skula
IPC: A61F2/18
CPC classification number: A61F2/186 , A61F5/08 , A61F2210/0004
Abstract: Novel bioabsorbable, universal kits used to form nasal implants are disclosed. The implants are useful in rhinoplasty and nasal reconstruction surgical procedures. The kit devices have a universal configuration and can be converted by the surgeon in the field into one or more individual nasal implant devices having different configurations and applications. The kits may have outlines of nasal implants thereon.
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公开(公告)号：US20210322624A1
公开(公告)日：2021-10-21
申请号：US17349535
申请日：2021-06-16
Applicant: Ethicon, Inc.
Inventor： Dennis D. Jamiolkowski , Christopher DeFelice , Sasa Andjelic , Brian M. Kelly , Marc Wisnudel , Daniel Steiger , Gaoyuan Gavin Chen
Abstract: Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.
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3.发明申请公开(公告)号：US20200000958A1
公开(公告)日：2020-01-02
申请号：US16021322
申请日：2018-06-28
Applicant: Ethicon, Inc.
Inventor： Dennis D. Jamiolkowski , Christopher DeFelice , Sasa Andjelic , Brian M. Kelly , Marc Wisnudel , Daniel Steiger , Gaoyuan Gavin Chen
Abstract: Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.
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公开(公告)号：US11058792B2
公开(公告)日：2021-07-13
申请号：US16021322
申请日：2018-06-28
Applicant: Ethicon, Inc.
Inventor： Dennis D. Jamiolkowski , Christopher DeFelice , Sasa Andjelic , Brian M. Kelly , Marc Wisnudel , Daniel Steiger , Gaoyuan Gavin Chen
Abstract: Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.
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Patent Agency Ranking
公开(公告)号：US20200149194A1
公开(公告)日：2020-05-14
申请号：US16183861
申请日：2018-11-08
Applicant: Ethicon, Inc.
Inventor： Gaoyuan Gavin Chen , Joseph Richard Vliet, JR. , Dominick Egidio
Abstract: A novel process is disclosed for extruding an absorbable glycolide/lactide block copolymer into multifilament suture fibers. The block copolymer preferably consists of about 50/50 mole % of Glycolide/Lactide in the center segment and the overall composition of the copolymer is about 90/10 mole % Glycolide/Lactide. The novel extrusion process comprises the steps of maintaining the temperatures of at least two, preferably three or more, of the extrusion zones in the range of about 5-50° C. below the polymer melting point. The multifilament suture made with the invention process from the segmented, glycolide-rich, poly(glycolide-co-lactide) copolymers of A-B-A type, where the B-segment is an amorphous prepolymer of glycolide and lactide in the molar ratio of about 50/50 glycolide/lactide, exhibit exceptionally high breaking strength retention (BSR) at 42 days post-implantation.
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公开(公告)号：US20130158677A1
公开(公告)日：2013-06-20
申请号：US13766048
申请日：2013-02-13
Applicant: Ethicon, Inc.
Inventor： Robert A. Rousseau , David C. Lindh, SR. , John R. Jacobs , IIya S. Koyfman , Gaoyuan Gavin Chen , Donald G. Hill
IPC: A61F2/02
CPC classification number: A61F2/02 , A61F2/0063 , A61F2002/0068 , A61F2210/0004
Abstract: An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries.
Abstract translation: 一种用于修复或加强组织或肌肉壁缺损的可植入假体，其包括包括至少一层不可吸收材料的第一复合结构，其中所述第一复合结构具有尺寸和形状以覆盖所述第一复合结构的至少一部分的中心部分 组织或肌肉壁缺损，并具有外周。 所述假体还包括具有加强的中心区域和外周边缘的第二结构，位于所述第一和第二结构之间的加强元件，并且具有大于所述第一和第二结构的外周边和刚度的至少 一个牵引元件联接到第二结构的加强中心区域。 第二结构基本上仅在它们各自的周边耦合到第一结构。
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公开(公告)号：US11596709B2
公开(公告)日：2023-03-07
申请号：US17349535
申请日：2021-06-16
Applicant: Ethicon, Inc.
Inventor： Dennis D. Jamiolkowski , Christopher DeFelice , Sasa Andjelic , Brian M. Kelly , Marc Wisnudel , Daniel Steiger , Gaoyuan Gavin Chen
Abstract: Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.
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公开(公告)号：US11136696B2
公开(公告)日：2021-10-05
申请号：US16183861
申请日：2018-11-08
Applicant: Ethicon, Inc.
Inventor： Gaoyuan Gavin Chen , Joseph Richard Vliet, Jr. , Dominick Egidio
Abstract: A novel process is disclosed for extruding an absorbable glycolide/lactide block copolymer into multifilament suture fibers. The block copolymer preferably consists of about 50/50 mole % of Glycolide/Lactide in the center segment and the overall composition of the copolymer is about 90/10 mole % Glycolide/Lactide. The novel extrusion process comprises the steps of maintaining the temperatures of at least two, preferably three or more, of the extrusion zones in the range of about 5-50° C. below the polymer melting point. The multifilament suture made with the invention process from the segmented, glycolide-rich, poly(glycolide-co-lactide) copolymers of A-B-A type, where the B-segment is an amorphous prepolymer of glycolide and lactide in the molar ratio of about 50/50 glycolide/lactide, exhibit exceptionally high breaking strength retention (BSR) at 42 days post-implantation.
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公开(公告)号：US20150230917A1
公开(公告)日：2015-08-20
申请号：US14704006
申请日：2015-05-05
Applicant: Ethicon, Inc.
Inventor： Krasimira Hristov , Gaoyuan Gavin Chen , Mark T. Mooney , James A. Matrunich , Jianxin Guo , Emil Richard Skula
IPC: A61F2/18
CPC classification number: A61F2/186 , A61F5/08 , A61F2210/0004
Abstract: Novel bioabsorbable, universal kits used to form nasal implants are disclosed. The implants are useful in rhinoplasty and nasal reconstruction surgical procedures. The kit devices have a universal configuration and can be converted by the surgeon in the field into one or more individual nasal implant devices having different configurations and applications. The kits may have outlines of nasal implants thereon.
Abstract translation: 公开了用于形成鼻腔植入物的新型生物可吸收的通用试剂盒。 植入物在鼻整形术和鼻重建手术中是有用的。 套件装置具有通用结构，并且可以由现场的外科医生转换成具有不同构造和应用的一个或多个单独的鼻植入装置。 试剂盒可能具有其上的鼻植入物的轮廓。
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