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公开(公告)号:US20220331475A1
公开(公告)日:2022-10-20
申请号:US17667787
申请日:2022-02-09
Applicant: Ethicon, Inc.
Inventor: Nir Nativ , Thomas Weindl , Benjamin D. Fitz , Gerard Llanos , Guanghui Zhang , Yi-Lan Wang , Meng Deng
Abstract: The present invention is directed to a hemostatic patch comprising a porous substrate and at least a pair of co-reactive polymer reagents comprising at least one nucleophilic polyalkylene oxide based component and at least one electrophilic polyalkylene oxide-based on the porous substrate in a molar ratio of about 0.2 to about 0.9:1 of primary nucleophilic groups in excess to available electrophilic groups. The present invention is also directed to processes for the manufacture and use of such hemostatic patches.