公开(公告)号：US11801324B2

公开(公告)日：2023-10-31

申请号：US16407503

申请日：2019-05-09

申请人： Ferrosan Medical Devices A/S ,  Ethicon Inc.

发明人： Peter Lund Hammershøj ,  Kristian Larsen ,  Douglas B. Johns ,  Nicole Smith ,  Michael Cardinale ,  Gabriella Ferrara ,  Guanghui Zhang

IPC分类号： A61L24/04 ,  A61B17/12 ,  A61L24/00 ,  A61B17/00

CPC分类号： A61L24/043 ,  A61B17/12186 ,  A61L24/0042 ,  A61B2017/00495 ,  A61L2400/04 ,  A61L2400/06

摘要： The present disclosure relates to a method for preparing a haemostatic composition comprising thrombin, the method comprising the step of reconstituting a dry thrombin directly in a paste, such as a paste comprising a biocompatible polymer. The haemostatic composition comprising thrombin may be prepared from a dry thrombin composition and a paste in a single step operation and be used for treatment of a wound.

公开(公告)号：US11517527B2

公开(公告)日：2022-12-06

申请号：US16180482

申请日：2018-11-05

申请人： Ethicon, Inc.

发明人： Nicole Smith ,  Michael Cardinale

IPC分类号： A61K9/00 ,  A61K9/12 ,  A61L24/00 ,  A61B17/00 ,  B01F23/235 ,  B01F25/451 ,  B01F33/501 ,  B01F35/71 ,  A61J1/20 ,  A61B17/12

摘要： A medical device for making foam includes a syringe having a plunger for dispensing a liquid from a liquid dispensing port, and a mixing chamber including a mixing chamber inlet, a mixing chamber outlet, a liquid flow channel extending between the mixing chamber inlet and the mixing chamber outlet, and a gas inlet channel that intersects with the liquid flow channel. The system has a gas cartridge containing the gas, a first gas conduit connected with the syringe, and a second gas conduit connected with the gas inlet channel. An actuator is coupled with the gas cartridge for releasing the gas into the first and second gas conduits. The released gas in the first gas conduit forces the plunger toward the liquid dispensing port for dispensing the liquid from the liquid dispensing port and into the liquid flow channel while the released gas in the second gas conduit flows into the gas inlet channel of the mixing chamber for mixing with the liquid in the liquid flow channel.

公开(公告)号：US20220218339A1

公开(公告)日：2022-07-14

申请号：US17706802

申请日：2022-03-29

申请人： Ethicon, Inc.

发明人： Simon Cohn ,  Michael Cardinale ,  Richard P. Fuchs ,  Matthew Rohr Daniel ,  Jeremy David Jarrett ,  Robert Nering ,  Anthony Miksza

IPC分类号： A61B17/068 ,  A61B17/064 ,  A61B17/10

摘要： An applicator instrument for dispensing surgical fasteners includes a housing, an elongated shaft, surgical fasteners disposed in the elongated shaft, a firing system for dispensing the surgical fasteners, a firing rod disposed within the elongated shaft and movable within a first plane, and an advancer disposed within the elongated shaft and moveable within a second plane. An actuator is coupled with the advancer for moving the advancer back and forth between retracted and extended positions. A staging assembly at the distal end of the elongated shaft aligns a leading surgical fastener with the first plane. The staging assembly includes a biasing device that is configured to be deflected away from the first plane by the advancer when the advancer is in the extended position and the staging assembly is configured to spring back into alignment with the first plane when the advancer returns back to the retracted position.

公开(公告)号：US10918381B2

公开(公告)日：2021-02-16

申请号：US15493898

申请日：2017-04-21

申请人： Ethicon, Inc.

发明人： Jianxin Guo ,  Michael Nordmeyer ,  Michael Cardinale ,  Simon Cohn ,  Mark D. Kenyon ,  Doug Souls ,  Danial Paul Ferreira

IPC分类号： A61B17/068 ,  A61B17/00 ,  A61B17/064 ,  A61F2/02 ,  A61B34/37 ,  A61B34/30 ,  A61B90/92 ,  A61B17/29 ,  A61B90/00 ,  A61B17/072

摘要： An applicator instrument for dispensing surgical fasteners includes an elongated shaft, a housing connected with the elongated shaft, a trigger, a gear train, and a firing system disposed in the housing. The trigger is squeezed for commencing a firing cycle. The firing system includes a storage reel, a spool connected to the storage reel, a drive wheel located distal to the storage reel and the spool, a constant torque spring having a proximal end connected to the spool and a distal end connected to the drive wheel, and a flexible member in contact with the drive wheel. The flexible member has a proximal end connected to the storage reel and a length configured to be driven by the drive wheel toward the distal end of the elongated shaft. During an energy storing stage, the gear train is coupled with the storage reel for rotating the storage reel in a counterclockwise direction, which, in turn, retracts and winds the flexible member onto the storage reel, which rotates the drive wheel in a counterclockwise direction and winds the constant torque spring from the spool onto the drive wheel for storing energy in the constant torque spring.

公开(公告)号：US10568627B2

公开(公告)日：2020-02-25

申请号：US15372241

申请日：2016-12-07

申请人： Ethicon, Inc.

发明人： Jianxin Guo ,  Simon Cohn ,  Michael Cardinale ,  Doug Souls ,  Jephté Augustin

IPC分类号： A61B17/08 ,  A61B17/10 ,  A61B17/072 ,  A61B17/064 ,  A61B17/068

摘要： A surgical fastener includes a first leg having a first distal barb and a first proximal barb that extend inwardly, and a second leg having a second distal barb and a second proximal barb that extend inwardly. A bridge interconnects proximal ends of the first and second legs. A first distance between opposing inner tips of the first and second distal barbs is greater than a second distance between opposing inner tips of the first and second proximal barbs. The first leg tapers inwardly between the proximal and distal ends thereof and has a cross-sectional area that is greater at the proximal end than at the distal end. The second leg tapers inwardly between the proximal and distal ends thereof and has a cross-sectional area that is greater at the proximal end than at the distal end. An insertion tool engages a crown on the proximal side of the bridge.

公开(公告)号：US20190021833A1

公开(公告)日：2019-01-24

申请号：US16143740

申请日：2018-09-27

申请人： Ethicon, Inc.

发明人： Jianxin Guo ,  Simon Cohn ,  Michael Cardinale ,  Doug Souls

IPC分类号： A61F2/00 ,  A61B17/06 ,  A61B1/313 ,  A61B17/00

摘要： Novel mesh implant positioning systems for use in laparoscopic body wall defect repairs, such as hernia defects, are disclosed. The systems utilize one or more bar members combined with surgical sutures and needles to position a mesh implant adjacent to a body wall defect without the need for stay sutures. Also disclosed are assemblies of the positioning systems with surgical mesh repair implants, and methods of repairing body wall defects such as hernias with the assemblies.

公开(公告)号：US20180153550A1

公开(公告)日：2018-06-07

申请号：US15494012

申请日：2017-04-21

申请人： Ethicon, Inc.

发明人： Doug Souls ,  Simon Cohn ,  Michael Cardinale ,  Jianxin Guo ,  Mark D. Kenyon ,  Jared Schneider ,  Danial Paul Ferreira ,  Xuelin Guo ,  Lindsay Epstein ,  Michael Nordmeyer

IPC分类号： A61B17/072 ,  A61B90/00 ,  A61B34/37 ,  A61B17/068 ,  A61F2/02

摘要： A method of dispensing surgical fasteners includes providing an applicator instrument having a housing with a cartridge opening, an elongated shaft extending from the housing, a firing system disposed within the housing for dispensing surgical fasteners, and an actuator for activating the firing system. The method includes forming a surgical opening in tissue, inserting a distal end of the elongated shaft into the surgical opening, inserting a cartridge containing a plurality of first surgical fasteners into the cartridge opening, and engaging the actuator for dispensing one of the first surgical fasteners from the distal end of the elongated shaft. While maintaining the distal end of the elongated shaft inside the surgical opening, the cartridge is removed from the cartridge opening, a second cartridge containing a plurality of second surgical fasteners is inserted into the cartridge opening, and the actuator is engaged for dispensing one of the second surgical fasteners from the distal end of the elongated shaft.

公开(公告)号：US20180153547A1

公开(公告)日：2018-06-07

申请号：US15493929

申请日：2017-04-21

申请人： Ethicon, Inc.

发明人： Simon Cohn ,  Michael Nordmeyer ,  Michael Cardinale ,  Jianxin Guo ,  Mark D. Kenyon ,  Doug Souls ,  Danial Paul Ferreira ,  Jared Schneider

IPC分类号： A61B17/072 ,  A61B17/068 ,  A61B34/37 ,  A61B90/00

摘要： An applicator instrument for dispensing surgical fasteners includes a housing having a cartridge opening, an elongated shaft extending from the housing, and a cartridge insertable into the cartridge opening, the cartridge having a plurality of surgical fasteners pre-loaded into the cartridge. The applicator instrument has a firing system disposed within the housing, and an actuator for activating the firing system to commence a firing cycle for removing one of the surgical fasteners from the cartridge and driving the removed surgical fastener from the housing to a distal end of the elongated shaft. In one embodiment, the cartridge includes a cartridge body having an upper end and a lower end insertable into the cartridge opening. The surgical fasteners are arrayed in a stack that extends between the upper and lower ends of the cartridge body. The cartridge has a constant force spring that normally urges the stack of surgical fasteners toward the lower end of the cartridge body for being fed into the firing system.

公开(公告)号：US20180028303A1

公开(公告)日：2018-02-01

申请号：US15222127

申请日：2016-07-28

申请人： Ethicon, Inc.

发明人： Jianxin Guo ,  Simon Cohn ,  Michael Cardinale ,  Doug Souls

IPC分类号： A61F2/00 ,  A61B17/06

CPC分类号： A61F2/0063 ,  A61B1/313 ,  A61B17/06004 ,  A61B2017/00951 ,  A61F2002/0072 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0058 ,  A61F2250/0059

摘要： Novel mesh implant positioning systems for use in laparoscopic body wall defect repairs, such as hernia defects, are disclosed. The systems utilize one or more bar members combined with surgical sutures and needles to position a mesh implant adjacent to a body wall defect without the need for stay sutures. Also disclosed are assemblies of the positioning systems with surgical mesh repair implants, and methods of repairing body wall defects such as hernias with the assemblies.

公开(公告)号：US09498211B2

公开(公告)日：2016-11-22

申请号：US14479450

申请日：2014-09-08

申请人： Ethicon, Inc.

发明人： Simon Cohn ,  Michael Cardinale ,  Richard P. Fuchs ,  Matthew David Daniel ,  Jeremy David Jarrett ,  Robert Nering ,  Anthony Miksza

IPC分类号： A61B17/064 ,  A61B17/068 ,  A61B17/10 ,  A61B17/29

CPC分类号： A61B17/0682 ,  A61B17/064 ,  A61B17/10 ,  A61B2017/2923 ,  A61B2017/2946 ,  A61B2090/0807

摘要： A method of securing a prosthetic device to tissue includes providing an applicator instrument including a housing, a shaft, surgical fasteners, a firing rod for dispensing the surgical fasteners from the shaft, a trigger, and an energy storing element. The method includes positioning a prosthetic device over tissue, juxtaposing a distal end of the shaft with the prosthetic device, and compressing the trigger for piloting the firing rod toward the distal end of the elongated shaft at a first rate of speed. The method includes preventing the firing rod from moving distally while building up energy in the energy storing element, and further compressing the trigger for releasing the firing rod for distal movement and transferring the built up energy for moving the firing rod toward the distal end of the elongated shaft at a second rate of speed that is greater than the first rate of speed.

摘要翻译： 一种将假体装置固定在组织上的方法包括提供包括壳体，轴，手术紧固件，用于从轴分配手术紧固件的击发杆，触发器和能量存储元件的施用器械。 该方法包括将假体装置定位在组织上，并将假肢装置的远端与假肢装置并置，并且以第一速度的速度压缩触发器以将发射杆引向细长轴的远端。 该方法包括防止发射杆在能量存储元件中建立能量的同时向远侧移动，并进一步压缩触发器以释放用于远端移动的发射杆，并传递用于将发射杆移动到远端的发射杆的建立能量 细长轴以大于第一速度速率的第二速度速度。