公开(公告)号：US08469577B2

公开(公告)日：2013-06-25

申请号：US13038278

申请日：2011-03-01

申请人： Eui Jeong Kang ,  Dongmin Yeo ,  Taeho Lee ,  Yong-Hoon Kwon ,  Min-Young Song ,  Seung Hwan Baek

发明人： Eui Jeong Kang ,  Dongmin Yeo ,  Taeho Lee ,  Yong-Hoon Kwon ,  Min-Young Song ,  Seung Hwan Baek

IPC分类号： F21V7/04

CPC分类号： G02B6/0078 ,  G02B6/0051 ,  G02B6/0068 ,  G02B6/0073 ,  G02B6/0081 ,  G02B6/0088 ,  G02B6/0091

摘要： A display apparatus with at least two light guide plates, each including a light incident surface and a light exiting surface, the light guide plates being spaced apart from each other so as to form a gap therebetween. The display apparatus also has a light source disposed adjacent to at least one side portion of the light guide plates to emit light to the light incident surface, a display panel positioned to receive light from the light exiting surfaces to facilitate display of an image, and a diffusion member. The diffusion member covers the gap, so as to diffuse light directed toward the display panel.

公开(公告)号：US20110235308A1

公开(公告)日：2011-09-29

申请号：US13038278

申请日：2011-03-01

申请人： Eui Jeong KANG ,  Dongmin Yeo ,  Taeho Lee ,  Yong-Hoon Kwon ,  Min-Young Song ,  Seung Hwan Baek

发明人： Eui Jeong KANG ,  Dongmin Yeo ,  Taeho Lee ,  Yong-Hoon Kwon ,  Min-Young Song ,  Seung Hwan Baek

IPC分类号： G02F1/13357

CPC分类号： G02B6/0078 ,  G02B6/0051 ,  G02B6/0068 ,  G02B6/0073 ,  G02B6/0081 ,  G02B6/0088 ,  G02B6/0091

摘要： A display apparatus with at least two light guide plates, each including a light incident surface and a light exiting surface, the light guide plates being spaced apart from each other so as to form a gap therebetween. The display apparatus also has a light source disposed adjacent to at least one side portion of the light guide plates to emit light to the light incident surface, a display panel positioned to receive light from the light exiting surfaces to facilitate display of an image, and a diffusion member. The diffusion member covers the gap, so as to diffuse light directed toward the display panel.

摘要翻译： 一种具有至少两个导光板的显示装置，每个导光板包括光入射表面和光出射表面，所述导光板彼此间隔开，以便在它们之间形成间隙。 显示装置还具有与导光板的至少一个侧部相邻设置的光源，以向光入射表面发光;定位成从光出射面接收光以便于图像显示的显示面板，以及 扩散构件。 扩散构件覆盖间隙，以便漫射指向显示面板的光。

公开(公告)号：US08883746B2

公开(公告)日：2014-11-11

申请号：US12521487

申请日：2007-12-27

申请人： Chang-Yuil Kang ,  SangHee Kim ,  Hyun-Jun Youn ,  Yoon-Sook Lee ,  Kyoo-A Lee ,  Taeho Lee ,  Dong Jae Baek ,  Minjae Cho

发明人： Chang-Yuil Kang ,  SangHee Kim ,  Hyun-Jun Youn ,  Yoon-Sook Lee ,  Kyoo-A Lee ,  Taeho Lee ,  Dong Jae Baek ,  Minjae Cho

IPC分类号： A61K31/7028 ,  A61K31/00 ,  C07H15/04 ,  C07H15/00

CPC分类号： C07H15/00 ,  Y02P20/55

摘要： Disclosed are novel α-galactosylceramide derivatives, pharmaceutically acceptable salts thereof, preparation methods thereof, and pharmaceutical compositions for use in an immune adjuvant containing the same as an active ingredient. The derivatives, in which the amide moiety of α-GalCer is bioisosterically replaced with a triazole moiety, direct cytokine secretion toward IL-4 rather than IFN-γand thus can be used as a therapeutic for autoimmune diseases regulated by IL-4, such as type 1 diabetes and multiple sclerosis.

摘要翻译： 公开了新型α-半乳糖神经酰胺衍生物，其药学上可接受的盐，其制备方法和用于含有其作为活性成分的免疫佐剂的药物组合物。 其中α-GalCer的酰胺部分被三唑部分生物电离置换的衍生物直接导致IL-4的细胞因子分泌而不是IFN-γ，因此可用作IL-4调节的自身免疫性疾病的治疗剂，例如 1型糖尿病和多发性硬化症。

公开(公告)号：US08608361B2

公开(公告)日：2013-12-17

申请号：US13351592

申请日：2012-01-17

申请人： JoongHyun Kim ,  Jinsung Choi ,  Byoung Dae Ye ,  Taeho Lee ,  Yongkyu Kang ,  Sangwon Lee

发明人： JoongHyun Kim ,  Jinsung Choi ,  Byoung Dae Ye ,  Taeho Lee ,  Yongkyu Kang ,  Sangwon Lee

IPC分类号： F21V33/00

CPC分类号： G02B6/0026 ,  G02B6/0076

摘要： A three-dimensional (“3D”) image display device includes a backlight unit. The backlight unit includes a light guide part including a plurality of light guide units. Each of the light guide units includes a light guide plate including a light emission surface through which supplied light is emitted, a bottom surface which faces the light emission surface, and side surfaces which connect the light emission surface to the bottom surface, a plurality of light sources which emit light toward at least one of the side surfaces, and a band pass filter between the side surface to which the light is emitted and the light sources.

摘要翻译： 三维（“3D”）图像显示装置包括背光单元。 背光单元包括具有多个导光单元的导光部。 每个导光单元包括导光板，该导光板包括发射供给的光的发光面，与发光面相对的底面，以及将发光面连接到底面的侧面，多个 向侧表面中的至少一个发射光的光源，以及在发射光的侧表面和光源之间的带通滤光器。

公开(公告)号：US07915405B2

公开(公告)日：2011-03-29

申请号：US12570492

申请日：2009-09-30

申请人： Young-Dae Gong ,  Taeho Lee ,  Moon-Kook Jeon ,  Heeyeong Cho ,  Jae Yang Kong ,  Gildon Choi ,  Dae Young Jeong ,  Soon-Hee Hwang

发明人： Young-Dae Gong ,  Taeho Lee ,  Moon-Kook Jeon ,  Heeyeong Cho ,  Jae Yang Kong ,  Gildon Choi ,  Dae Young Jeong ,  Soon-Hee Hwang

IPC分类号： C07D413/14 ,  C07D413/10 ,  C07D417/10 ,  C07D417/14 ,  C07D277/54 ,  A61K31/5377 ,  A61K31/497 ,  A61K31/454 ,  A61K31/431

CPC分类号： C07D277/56 ,  C07D417/04 ,  C07D417/12

摘要： Disclosed herein are 2,4-disubstituted-5-aminocarbonyl-1,3-thiazole derivatives, a preparation method thereof, and a therapeutic agent for treating inflammatory diseases induced by SPC, which contains the derivative as an active ingredient. The anti-inflammatory effect of the 2,4-disubstituted-5-aminocarbonyl-1,3-thiazole derivatives was analyzed through a test employing human dermal cells and an animal test using mice and, as a result, it was found that the derivatives showed excellent inhibitory activity on SPC receptor compared to thiazole derivatives known in the prior art. Thus, the 2,4-disubstituted-5-aminocarbonyl-1,3-thiazole derivatives or pharmaceutically acceptable salts thereof are useful as active ingredients in therapeutic agents for treating inflammatory diseases, such as inflammation, pruritus and skin infection, which appear in atopic dermatitis and other diseases induced by SPC activity. wherein R1, R2, R3 and R4 are as defined in the specification.

摘要翻译： 本文公开了2,4-二取代-5-氨基羰基-1,3-噻唑衍生物，其制备方法和用于治疗由SPC诱导的炎症性疾病的治疗剂，其含有该衍生物作为活性成分。 通过使用人真皮细胞的试验和使用小鼠的动物试验分析2,4-二取代-5-氨基羰基-1,3-噻唑衍生物的抗炎作用，结果发现衍生物 与现有技术中已知的噻唑衍生物相比，对SPC受体显示出优异的抑制活性。 因此，2,4-二取代-5-氨基羰基-1,3-噻唑衍生物或其药学上可接受的盐可用作用于治疗炎性疾病如炎症，瘙痒和皮肤感染的治疗剂中的活性成分，其出现在特应性 皮炎和其他由SPC活动引起的疾病。 其中R1，R2，R3和R4如说明书中所定义。

公开(公告)号：US20110267841A1

公开(公告)日：2011-11-03

申请号：US13086167

申请日：2011-04-13

申请人： Myung-Woon Lee ,  Jung-Wook Paek ,  Taeseok Jang ,  Jinsung Choi ,  Hyungguel Kim ,  Sangduk Lee ,  Taeho Lee

发明人： Myung-Woon Lee ,  Jung-Wook Paek ,  Taeseok Jang ,  Jinsung Choi ,  Hyungguel Kim ,  Sangduk Lee ,  Taeho Lee

IPC分类号： F21V7/22

CPC分类号： G02B6/0091 ,  G02B6/003 ,  G02B6/0031 ,  G02B6/0068 ,  G02B6/0073

摘要： Disclosed is a display apparatus. The display apparatus includes a light guide plate, a light source section, a light guide member, and a display panel. The light guide plate has a light incident surface and a light exit surface connected to the light incident surface. The light source section faces the light incident surface and has a plurality of light sources to output the light. The light guide member has a plate-like shape with first and second surfaces facing each other, in which the first surface contacts the light source section, and the second surface contacts the light incident surface, and guides light to the light guide plate. The display panel receives light output through the light exit surface to display an image.

摘要翻译： 公开了一种显示装置。 显示装置包括导光板，光源部，导光部件和显示面板。 导光板具有与光入射面连接的光入射面和光出射面。 光源部分面向光入射表面并具有多个光源以输出光。 导光构件具有第一和第二表面彼此相对的板状，其中第一表面接触光源部分，并且第二表面接触光入射表面，并将光引导到导光板。 显示面板通过光出射面接收光输出以显示图像。

公开(公告)号：US20100145043A1

公开(公告)日：2010-06-10

申请号：US12570492

申请日：2009-09-30

申请人： Young-Dae Gong ,  Taeho Lee ,  Moon-Kook Jeon ,  Heeyeong Cho ,  Jae Yang Kong ,  Gildon Choi ,  Dae Young Jeong ,  Soon-Hee Hwang

发明人： Young-Dae Gong ,  Taeho Lee ,  Moon-Kook Jeon ,  Heeyeong Cho ,  Jae Yang Kong ,  Gildon Choi ,  Dae Young Jeong ,  Soon-Hee Hwang

IPC分类号： C07D417/14 ,  C07D417/04 ,  C07D277/56

CPC分类号： C07D277/56 ,  C07D417/04 ,  C07D417/12

摘要： Disclosed herein are 2,4-disubstituted-5-aminocarbonyl-1,3-thiazole derivatives, a preparation method thereof, and a therapeutic agent for treating inflammatory diseases induced by SPC, which contains the derivative as an active ingredient. The anti-inflammatory effect of the 2,4-disubstituted-5-aminocarbonyl-1,3-thiazole derivatives was analyzed through a test employing human dermal cells and an animal test using mice and, as a result, it was found that the derivatives showed excellent inhibitory activity on SPC receptor compared to thiazole derivatives known in the prior art. Thus, the 2,4-disubstituted-5-aminocarbonyl-1,3-thiazole derivatives or pharmaceutically acceptable salts thereof are useful as active ingredients in therapeutic agents for treating inflammatory diseases, such as inflammation, pruritus and skin infection, which appear in atopic dermatitis and other diseases induced by SPC activity. wherein R1, R2, R3 and R4 are as defined in the specification.

摘要翻译： 本文公开了2,4-二取代-5-氨基羰基-1,3-噻唑衍生物，其制备方法和用于治疗由SPC诱导的炎症性疾病的治疗剂，其含有该衍生物作为活性成分。 通过使用人真皮细胞的试验和使用小鼠的动物试验分析2,4-二取代-5-氨基羰基-1,3-噻唑衍生物的抗炎作用，结果发现衍生物 与现有技术中已知的噻唑衍生物相比，对SPC受体显示出优异的抑制活性。 因此，2,4-二取代-5-氨基羰基-1,3-噻唑衍生物或其药学上可接受的盐可用作用于治疗炎性疾病如炎症，瘙痒和皮肤感染的治疗剂中的活性成分，其出现在特应性 皮炎和其他由SPC活动引起的疾病。 其中R1，R2，R3和R4如说明书中所定义。

公开(公告)号：US20100104590A1

公开(公告)日：2010-04-29

申请号：US12521487

申请日：2007-12-27

申请人： Chang-Yuil Kang ,  SangHee Kim ,  Hyun-Jun Youn ,  Yoon-Sook Lee ,  Kyoo-A Lee ,  Taeho Lee ,  Dong Jae Baek ,  Minjae Cho

发明人： Chang-Yuil Kang ,  SangHee Kim ,  Hyun-Jun Youn ,  Yoon-Sook Lee ,  Kyoo-A Lee ,  Taeho Lee ,  Dong Jae Baek ,  Minjae Cho

IPC分类号： A61K31/7028 ,  C07H15/04 ,  A61K39/00 ,  A61P37/00

CPC分类号： C07H15/00 ,  Y02P20/55

摘要： Disclosed are novel α-galactosylceramide derivatives, pharmaceutically acceptable salts thereof, preparation methods thereof, and pharmaceutical compositions for use in an immune adjuvant containing the same as an active ingredient. The derivatives, in which the amide moiety of α-GalCer is bioisosterically replaced with a triazole moiety, direct cytokine secretion toward IL-4 rather than IFN-γ and thus can be used as a therapeutic for autoimmune diseases regulated by IL-4, such as type 1 diabetes and multiple sclerosis.

摘要翻译： 公开了新型α-半乳糖神经酰胺衍生物，其药学上可接受的盐，其制备方法和用于含有其作为活性成分的免疫佐剂的药物组合物。 其中α-GalCer的酰胺部分被三唑部分生物电化学取代的衍生物直接导致细胞因子分泌IL-4而不是IFN-γ，因此可以用作IL-4调节的自身免疫疾病的治疗剂，例如 作为1型糖尿病和多发性硬化。