公开(公告)号：US20230193231A1

公开(公告)日：2023-06-22

申请号：US18045829

申请日：2022-10-11

Applicant: Factor Bioscience Inc.

Inventor： Matthew ANGEL ,  Franklin KOSTAS ,  Mitchell KOPACZ ,  Christopher ROHDE

IPC: C12N9/22 ,  C12N5/071

CPC classification number: C12N9/22 ,  C12N5/0629

Abstract: The present invention relates in part to nucleic acids encoding gene editing proteins, including novel engineered variants.

公开(公告)号：US20220106256A1

公开(公告)日：2022-04-07

申请号：US17553564

申请日：2021-12-16

Applicant: FACTOR BIOSCIENCE INC.

Inventor： Matthew ANGEL ,  Franklin KOSTAS ,  Christopher ROHDE

IPC: C07C215/24 ,  A61K9/127

Abstract: The present invention relates in part to novel cationic lipids and their use, e.g., in delivering nucleic acids to cells.

公开(公告)号：US20210024907A1

公开(公告)日：2021-01-28

申请号：US17041787

申请日：2019-03-27

Applicant: Factor Bioscience Inc.

Inventor： Matthew ANGEL ,  Christopher ROHDE ,  Simon MOORE ,  Franklin KOSTAS ,  Jasmine HARRIS

IPC: C12N9/22 ,  A61K9/127 ,  C07K14/50 ,  C07K14/54 ,  A61P37/06 ,  A61P25/00

Abstract: The present invention relates in part to nucleic acids, including nucleic acids encoding proteins, therapeutics and cosmetics comprising nucleic acids, methods for delivering nucleic acids to cells, tissues, organs, and patients, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, therapeutics, and cosmetics produced using these methods, kits, and devices.

公开(公告)号：US20230373903A1

公开(公告)日：2023-11-23

申请号：US18362789

申请日：2023-07-31

Applicant: Factor Bioscience Inc.

Inventor： Matthew ANGEL ,  Franklin KOSTAS ,  Christopher ROHDE

IPC: C07C215/24 ,  A61K9/127

CPC classification number: C07C215/24 ,  A61K9/1272

Abstract: The present invention relates in part to novel cationic lipids and their use, e.g., in delivering nucleic acids to cells.

公开(公告)号：US20210032192A1

公开(公告)日：2021-02-04

申请号：US16930901

申请日：2020-07-16

Applicant: Factor Bioscience Inc.

Inventor： Matthew ANGEL ,  Franklin KOSTAS ,  Christopher ROHDE

IPC: C07C215/24 ,  A61K9/127

Abstract: The present invention relates in part to novel cationic lipids and their use, e.g., in delivering nucleic acids to cells.