CONTINUOUS BIOPROCESSING CENTRIFUGE ROTOR
    1.
    发明公开

    公开(公告)号:US20230234075A1

    公开(公告)日:2023-07-27

    申请号:US18002676

    申请日:2021-08-11

    Inventor: Sina PIRAMOON

    CPC classification number: B04B11/02 B04B5/0428 B04B5/0442 B04B9/12 B04B7/085

    Abstract: A rotor assembly (10, 150, 270, 310) and method of using the rotor assembly (10, 150, 270, 310). The rotor assembly (10, 150, 270, 310) includes a bio-process bag (48), a drum (46) that receives a lower portion of the bag (48), and a pressure ring (50). A holder (54, 182) couples an upper portion of the bag (48) to the pressure ring (50). The pressure ring (50) is coupled to the drum (46) to define an interior space that contains the bag (48). A liquid transport assembly (35, 178, 272) passes through an opening in the holder (54, 182) so that liquids can be added to, and removed from, the bag (48) without removing the rotor (16, 154) from the centrifuge. A bearing assembly (190) in the holder (54, 182) couples the liquid transport assembly (35, 178, 272) to the rotor (16, 154), and enables the liquid transport assembly (35, 178, 272) to remain stationary while the rotor (16, 154) rotates around it. One or more seal assemblies (276, 312) provide a fluid-tight seal against the outer portion of the liquid transport assembly (35, 178, 272), and prevent fluids from leaking from the bag (48) during centrifugation.

    ULTRA-HIGH-SPEED ROTOR
    2.
    发明公开

    公开(公告)号:US20230415168A1

    公开(公告)日:2023-12-28

    申请号:US18252385

    申请日:2021-10-27

    Inventor: Sina PIRAMOON

    CPC classification number: B04B5/0414 B04B7/02 B04B9/14 B04B7/08 B04B2007/025

    Abstract: A rotor (10) for use in a centrifuge includes a rotor body (12), a drive hub (20), and a balance ring (16, 160). The rotor body (12) includes an elongated bore (32) extending along its axis of rotation (24), and an upper surface (26) having an annular groove (42). The drive hub (20) is mounted within the elongated bore (32), and includes a drive portion (138) having a cross-sectional shape that is complementary to the cross-sectional shape of the elongated bore (32). The drive hub (20) applies torque to the rotor body (12) via engagement of the drive portion (138) with the lower bore opening (36) of the rotor body (12). The balance ring (16, 160) is positioned in the annular groove (42), and includes a plurality of apertures (78, 163) formed in an upper surface (90, 170) thereof. Each of the apertures (78, 163) is configured to receive a weight (80, 164) so that the rotor (10) can be balanced by selectively adding weights (80, 164) to one or more of the apertures (78, 163).

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