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公开(公告)号：US10508088B2
公开(公告)日：2019-12-17
申请号：US16202207
申请日：2018-11-28
发明人： Jennifer Lee , Nicholas Barczak , Jaime A. Escobedo , Chiara Conti , Bingsong Han , David R. Lancia, Jr. , Cuixian Liu , Matthew W. Martin , Pui Yee Ng , Aleksandra Rudnitskaya , Jennifer R. Thomason , Xiaozhang Zheng
IPC分类号： C07D263/58 , A61P35/00 , A61K31/403 , A61K31/404 , A61K31/4178 , A61K31/4184 , A61K31/4188 , A61K31/4192 , A61K31/422 , A61K31/423 , A61K31/4245 , A61K31/427 , A61K31/428 , A61K31/435 , A61K31/437 , A61K31/438 , A61K31/4439 , A61K31/4709 , A61K31/4985 , A61K31/506 , A61K31/52 , A61K31/5377 , A61K31/5383 , A61K45/06 , C07C53/06 , C07D209/40 , C07D209/54 , C07D221/20 , C07D235/30 , C07D277/82 , C07D401/04 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07D405/04 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/06 , C07D473/00 , C07D487/04 , C07D491/056 , C07D491/107 , C07D498/04
摘要： The present invention provides methods and uses of inhibitors of histone deacetylase 11 (HDAC11) in the treatment of diseases and/or disorders, such as, for example, cell proliferative diseases.
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公开(公告)号：US20200079744A1
公开(公告)日：2020-03-12
申请号：US16688469
申请日：2019-11-19
发明人： Jennifer Lee , Nicholas Barczak , Jaime A. Escobedo , Chiara Conti , Bingsong Han , David R. Lancia, JR. , Cuixian Liu , Matthew W. Martin , Pui Yee Ng , Aleksandra Rudnitskaya , Jennifer R. Thomason , Xiaozhang Zheng
IPC分类号： C07D263/58 , A61P35/00 , A61K31/403 , A61K31/404 , A61K31/4178 , A61K31/4184 , A61K31/4188 , A61K31/4192 , A61K31/422 , A61K31/423 , A61K31/4245 , A61K31/427 , A61K31/428 , A61K31/435 , A61K31/437 , A61K31/438 , A61K31/4439 , A61K31/4709 , A61K31/4985 , A61K31/506 , A61K31/52 , A61K31/5377 , A61K31/5383 , A61K45/06 , C07C53/06 , C07D209/40 , C07D209/54 , C07D221/20 , C07D235/30 , C07D277/82 , C07D401/04 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07D405/04 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/06 , C07D473/00 , C07D487/04 , C07D491/056 , C07D491/107 , C07D498/04
摘要： The present invention provides methods and uses of inhibitors of histone deacetylase 11 (HDAC11) in the treatment of diseases and/or disorders, such as, for example, cell proliferative diseases.
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公开(公告)号：US10538496B2
公开(公告)日：2020-01-21
申请号：US16202210
申请日：2018-11-28
发明人： Jennifer Lee , Pearlie Burnette , Srikumar Chellappan , Nicholas Barczak , Jaime A. Escobedo , Chiara Conti , Bingsong Han , David R. Lancia, Jr. , Cuixian Liu , Matthew W. Martin , Pui Yee Ng , Aleksandra Rudnitskaya , Jennifer R. Thomason , Xiaozhang Zheng
IPC分类号： C07D263/58 , A61P35/00 , A61K31/403 , A61K31/404 , A61K31/4178 , A61K31/4184 , A61K31/4188 , A61K31/4192 , A61K31/422 , A61K31/423 , A61K31/4245 , A61K31/427 , A61K31/428 , A61K31/435 , A61K31/437 , A61K31/438 , A61K31/4439 , A61K31/4709 , A61K31/4985 , A61K31/506 , A61K31/52 , A61K31/5377 , A61K31/5383 , A61K45/06 , C07C53/06 , C07D209/40 , C07D209/54 , C07D221/20 , C07D235/30 , C07D277/82 , C07D401/04 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07D405/04 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/06 , C07D473/00 , C07D487/04 , C07D491/056 , C07D491/107 , C07D498/04
摘要： The present invention provides methods and uses of inhibitors of histone deacetylase 11 (HDAC11) in the treatment of diseases and/or disorders, such as, for example, cell proliferative diseases.
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公开(公告)号：US20190084946A1
公开(公告)日：2019-03-21
申请号：US16202210
申请日：2018-11-28
发明人： Jennifer Lee , Pearlie Burnette , Srikumar Chellappan , Nicholas Barczak , Jaime A. Escobedo , Chiara Conti , Bingsong Han , David R. Lancia, JR. , Cuixian Liu , Matthew W. Martin , Pui Yee Ng , Aleksandra Rudnitskaya , Jennifer R. Thomason , Xiaozhang Zheng
IPC分类号： C07D263/58 , C07D401/04 , C07C53/06 , C07D235/30 , C07D221/20 , C07D209/54 , C07D209/40 , A61K45/06 , A61K31/5383 , A61K31/5377 , A61K31/52 , A61K31/506 , A61K31/4985 , A61K31/4709 , A61K31/4439 , A61K31/438 , A61K31/437 , A61K31/435 , A61K31/428 , C07D498/04 , C07D491/107 , C07D491/056 , C07D487/04 , C07D473/00 , C07D417/06 , C07D413/14 , C07D413/12 , C07D413/06 , C07D405/04 , C07D403/06 , C07D403/04 , C07D401/14 , C07D401/06 , A61K31/427 , A61K31/4245 , A61K31/423 , A61K31/422 , A61K31/4192 , A61K31/4188 , A61K31/4184 , A61K31/4178 , A61K31/404 , A61K31/403 , A61P35/00 , C07D277/82
CPC分类号： C07D263/58 , A61K31/403 , A61K31/404 , A61K31/4178 , A61K31/4184 , A61K31/4188 , A61K31/4192 , A61K31/422 , A61K31/423 , A61K31/4245 , A61K31/427 , A61K31/428 , A61K31/435 , A61K31/437 , A61K31/438 , A61K31/4439 , A61K31/4709 , A61K31/4985 , A61K31/506 , A61K31/52 , A61K31/5377 , A61K31/5383 , A61K45/06 , A61P35/00 , C07C53/06 , C07D209/40 , C07D209/54 , C07D221/20 , C07D235/30 , C07D277/82 , C07D401/04 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07D405/04 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/06 , C07D473/00 , C07D487/04 , C07D491/056 , C07D491/107 , C07D498/04
摘要： The present invention provides methods and uses of inhibitors of histone deacetylase 11 (HDAC11) in the treatment of diseases and/or disorders, such as, for example, cell proliferative diseases.
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公开(公告)号：US20180127386A1
公开(公告)日：2018-05-10
申请号：US15789869
申请日：2017-10-20
发明人： Jennifer Lee , Pearlie Burnette , Srikumar Chellappan , Nicholas Barczak , Jaime A. Escobedo , Chiara Conti , Bingsong Han , David R. Lancia, JR. , Cuixian Liu , Matthew W. Martin , Pui Yee Ng , Aleksandra Rudnitskaya , Jennifer R. Thomason , Xiaozhang Zheng
IPC分类号： C07D263/58 , A61P35/00 , A61K31/423 , C07D413/12 , A61K31/4439 , A61K31/506 , C07D277/82 , A61K31/428 , C07D235/30 , A61K31/4184 , C07C53/06 , C07D209/40 , A61K31/404 , C07D473/00 , A61K31/52 , C07D487/04 , A61K31/4985 , C07D498/04 , A61K31/437 , C07D491/056 , A61K31/4188 , A61K31/5383 , C07D401/04 , A61K31/4709 , C07D405/04 , A61K31/4178 , C07D403/04 , A61K31/5377 , C07D209/54 , A61K31/403 , C07D413/06 , A61K31/422 , C07D401/14 , C07D401/06 , C07D413/14 , A61K31/4245 , C07D417/06 , A61K31/427 , C07D403/06 , A61K31/4192 , C07D221/20 , A61K31/438 , C07D491/107 , A61K31/435 , A61K45/06
CPC分类号： C07D263/58 , A61K31/403 , A61K31/404 , A61K31/4178 , A61K31/4184 , A61K31/4188 , A61K31/4192 , A61K31/422 , A61K31/423 , A61K31/4245 , A61K31/427 , A61K31/428 , A61K31/435 , A61K31/437 , A61K31/438 , A61K31/4439 , A61K31/4709 , A61K31/4985 , A61K31/506 , A61K31/52 , A61K31/5377 , A61K31/5383 , A61K45/06 , A61P35/00 , C07C53/06 , C07D209/40 , C07D209/54 , C07D221/20 , C07D235/30 , C07D277/82 , C07D401/04 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07D405/04 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/06 , C07D473/00 , C07D487/04 , C07D491/056 , C07D491/107 , C07D498/04
摘要： The present invention provides methods and uses of inhibitors of histone deacetylase 11 (HDAC11) in the treatment of diseases and/or disorders, such as, for example, cell proliferative diseases.
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公开(公告)号：US20190084945A1
公开(公告)日：2019-03-21
申请号：US16202207
申请日：2018-11-28
发明人： Jennifer Lee , Nicholas Barczak , Jaime A. Escobedo , Chiara Conti , Bingsong Han , David R. Lancia, JR. , Cuixian Liu , Matthew W. Martin , Pui Yee Ng , Aleksandra Rudnitskaya , Jennifer R. Thomason , Xiaozhang Zheng
IPC分类号： C07D263/58 , C07D401/04 , C07C53/06 , C07D235/30 , C07D221/20 , C07D209/54 , C07D209/40 , A61K45/06 , A61K31/5383 , A61K31/5377 , A61K31/52 , A61K31/506 , A61K31/4985 , A61K31/4709 , A61K31/4439 , A61K31/438 , A61K31/437 , A61K31/435 , A61K31/428 , C07D498/04 , C07D491/107 , C07D491/056 , C07D487/04 , C07D473/00 , C07D417/06 , C07D413/14 , C07D413/12 , C07D413/06 , C07D405/04 , C07D403/06 , C07D403/04 , C07D401/14 , C07D401/06 , A61K31/427 , A61K31/4245 , A61K31/423 , A61K31/422 , A61K31/4192 , A61K31/4188 , A61K31/4184 , A61K31/4178 , A61K31/404 , A61K31/403 , A61P35/00 , C07D277/82
CPC分类号： C07D263/58 , A61K31/403 , A61K31/404 , A61K31/4178 , A61K31/4184 , A61K31/4188 , A61K31/4192 , A61K31/422 , A61K31/423 , A61K31/4245 , A61K31/427 , A61K31/428 , A61K31/435 , A61K31/437 , A61K31/438 , A61K31/4439 , A61K31/4709 , A61K31/4985 , A61K31/506 , A61K31/52 , A61K31/5377 , A61K31/5383 , A61K45/06 , A61P35/00 , C07C53/06 , C07D209/40 , C07D209/54 , C07D221/20 , C07D235/30 , C07D277/82 , C07D401/04 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07D405/04 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/06 , C07D473/00 , C07D487/04 , C07D491/056 , C07D491/107 , C07D498/04
摘要： The present invention provides methods and uses of inhibitors of histone deacetylase 11 (HDAC11) in the treatment of diseases and/or disorders, such as, for example, cell proliferative diseases.
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