公开(公告)号：US20190013194A1

公开(公告)日：2019-01-10

申请号：US15556109

申请日：2015-11-23

Applicant: FUDAN UNIVERSITY

Inventor： Qiankun DANG ,  Xiaodong XIE ,  Fuxing XU ,  Yinjuan CHEN ,  Chuanfan DING

IPC: H01J49/42 ,  H01J49/16 ,  H01J49/06

Abstract: The present invention relates to the technical field of mass analysis instruments. Disclosed is an ion excitation method in a linear ion trap. The method comprises: in a linear ion trap, and at an ion collision-induced dissociation stage, simultaneously applying an auxiliary excitation signal in radial X and Y directions thereof; increasing the kinetic energy of ions in the two directions, thereby increasing collisions with a center gas to cause dissociation; and converting the kinetic energy to internal energy to achieve tandem mass spectrometry analysis. The kinetic energy in the X and Y directions of the ion is increased, and compared to a conventional dissociation method in which ions are primarily excited in one direction, more kinetic energy is converted to internal energy, thus improving dissociation efficiency, shortening reaction time, and addressing a low mass cutoff effect in the ion trap.