公开(公告)号：US20180356399A1

公开(公告)日：2018-12-13

申请号：US15618151

申请日：2017-06-09

Applicant: FUJIFILM Corporation ,  The General Hospital Corporation

Inventor： Koju ITO ,  Chihaya KAKINUMA ,  Shinji MIMA ,  Daichi HIKIMOTO ,  Craig M Neville ,  Cathryn A Sundback

IPC: G01N33/50

CPC classification number: G01N33/5088 ,  G01N33/5029 ,  G01N33/5064

Abstract: The present disclosure provides a blood vessel model including: a pair of channel members, mutually opposing each other, each of which includes an opposing face in which a respective microchannel is formed; and a porous membrane that includes plural through-holes penetrating in a thickness direction, that is disposed between the opposing faces of the pair of channel members, and that partitions between the microchannels, wherein the porous membrane is provided with a vascular endothelial cell layer so as to cover one face facing one of the microchannels, an average opening diameter of the through-holes is from 1 μm to 20 μm, and an opening coverage ratio of the through-holes is from 30% to 70%.

公开(公告)号：US20220228108A1

公开(公告)日：2022-07-21

申请号：US17658446

申请日：2022-04-08

Applicant: FUJIFILM CORPORATION

Inventor： Keisuke OKU ,  Daichi HIKIMOTO ,  Takahiro OBA ,  Kenichi YASUDA ,  Hiroyuki YUKAWA

IPC: C12N5/00

Abstract: There is provided a cell culture base material having a porous membrane having an opening ratio of 30% to 70% and an extracellular matrix with which an inside of a hole of the porous membrane is filled. There is also provided a cell culture base material with cells having a cell layer on at least one surface of the cell culture base material.