公开(公告)号：US20150290359A1

公开(公告)日：2015-10-15

申请号：US14751511

申请日：2015-06-26

Applicant: FUJIFILM CORPORATION ,  JAPAN TISSUE ENGINEERING CO., LTD.

Inventor： Kazutaka OGIWARA ,  Kazuhiro YAMAGUCHI ,  Tasuku SASAKI ,  Eiko GOTO ,  Katsura SUGAWARA ,  Ken-ichiro HATA

IPC: A61L27/22 ,  A61F2/10 ,  A61L27/58 ,  A61L27/60 ,  A61L27/56

CPC classification number: A61L27/222 ,  A61F2/105 ,  A61F2210/0076 ,  A61L27/56 ,  A61L27/58 ,  A61L27/60 ,  A61L2430/34

Abstract: Artificial dermis for transplantation includes a wound contact layer that includes a porous sheet consisting of a biodegradable material, the porous sheet satisfying the following Equation, Equation: X2/X1≦0.8. In the porous sheet, when a line parallel to a wound contact face and a line perpendicular to a wound contact face of equal length are drawn, X1 represents a number of points of intersection between the line parallel to the wound contact face and pore walls; and X2 represents a number of points of intersection between the line perpendicular to the wound contact face and pore walls.

Abstract translation: 用于移植的人造真皮包括伤口接触层，其包括由可生物降解材料组成的多孔片，满足以下等式的多孔片，等式：X2 / X1＆N1; 0.8。 在多孔片材中，当绘制平行于伤口接触面的线和垂直于相同长度的伤口接触面的线时，X1表示平行于伤口接触面的线与孔壁之间的交点数; X2表示与伤口接触面垂直的线与孔壁的交点数。

公开(公告)号：US20160082148A1

公开(公告)日：2016-03-24

申请号：US14851467

申请日：2015-09-11

Applicant: FUJIFILM CORPORATION

Inventor： Koju ITO ,  Souichi KOHASHI ,  Hidekazu YAMAZAKI ,  Kenichiro HATA ,  Katsura SUGAWARA ,  Eiko GOTO ,  Masatsugu SHIMOMURA ,  Hiroshi YABU ,  Takahito KAWANO

IPC: A61L27/18 ,  A61L27/56

CPC classification number: A61L31/06 ,  A61L15/425 ,  A61L15/58 ,  A61L15/64 ,  C08L67/04

Abstract: Disclosed is a film which is able to suppress agglutination by being continuously adhered to an adhesion target portion in a biological body while suppressing a position shift. A film includes an adhesive and an adhesion inhibiting layer. The adhesive layer absorbs and maintains a liquid in a plurality of pores which are opened in one film surface and has a capillary force for adhering the adhesive layer to a first-cell group. The adhesive layer is formed of a biodegradable polymer. The adhesion inhibiting layer configures the other film surface, and inhibits adhesion between a second-cell group which is different from the first-cell group and the adhesive layer. In the adhesive layer, the pore is formed not to be penetrated in a thickness direction of the film, and thus the first-cell group and the second-cell group are separated into the one film surface side and the other film surface side.

Abstract translation: 公开了一种能够通过在抑制位置偏移的同时在生物体中连续粘附到粘合目标部分来抑制凝集的膜。 膜包括粘合剂和粘附抑制层。 粘合剂层吸收并保持在一个膜表面中打开的多个孔中的液体，并且具有用于将粘合剂层粘合到第一电池组的毛细管力。 粘合剂层由可生物降解的聚合物形成。 粘合抑制层构成另一个膜表面，并且抑制不同于第一电池组的第二电池组与粘合剂层之间的粘合。 在粘合剂层中，形成不在膜的厚度方向上穿透的孔，因此第一电池组和第二电池组分离成一个膜表面侧和另一个膜表面侧。