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公开(公告)号:US20210380633A1
公开(公告)日:2021-12-09
申请号:US17409692
申请日:2021-08-23
申请人: FUJIFILM CORPORATION
发明人: Yosuke YAMAMOTO , Kazuhei KANEKO , Motomasa TAKAHASHI , Makoto TAKAHASHI , Mika IMAMURA , Hirotaka SATOU , Hirofumi OMURA , Yuji YOSHIMITSU , Keita TANAKA , Daisuke NAKAGAWA
摘要: Provided are a method for producing a peptide compound including a step of using an aromatic heterocyclic compound represented by Formula (1) represented by Formula (1); a protective group-forming reagent including the compound; and the compound. In Formula (1), a ring A represents an aromatic heterocyclic ring, YA's each independently represent —OH, —NHR, —SH, or —X0, where X0 represents Cl, Br, or I, RA and RC each independently represent an aliphatic hydrocarbon group or an organic group having an aliphatic hydrocarbon group, RBs' each independently represent a monovalent aliphatic hydrocarbon group, a (1+c)-valent aromatic group, or a (1+c)-valent heteroaromatic group, where, in a case where both a and c is 0, RB is a monovalent aliphatic hydrocarbon group, and the number of carbon atoms in at least one aliphatic hydrocarbon group of RA, RB, or RC is 12 or more.
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公开(公告)号:US20210380634A1
公开(公告)日:2021-12-09
申请号:US17408474
申请日:2021-08-22
申请人: FUJIFILM CORPORATION
发明人: Yosuke YAMAMOTO , Kazuhei KANEKO , Motomasa TAKAHASHI , Makoto TAKAHASHI , Mika IMAMURA , Hirotaka SATOU , Hirofumi OMURA , Yuji YOSHIMITSU , Daisuke NAKAGAWA , Keita TANAKA
摘要: Provided are a method for producing a peptide compound including a step of using a condensed polycyclic aromatic hydrocarbon compound represented by Formula (1); a protective group-forming reagent including the compound; and the compound. In Formula (1), a ring A represents a condensed polycyclic aromatic hydrocarbon ring, YA's each independently represent —CH2OH, —CH2NHR, —CH2SH, or —CH2X0, where R represents a hydrogen atom, an alkyl group, or an aralkyl group, and X0 represents Cl, Br, or I, k represents an integer of 1 to 5, n represents 1 or 2, and RA's each independently represent an aliphatic hydrocarbon group or an organic group having an aliphatic hydrocarbon group.
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