公开(公告)号：US20220112233A1

公开(公告)日：2022-04-14

申请号：US17558540

申请日：2021-12-21

Applicant: FUJIFILM CORPORATION

Inventor： Yosuke YAMAMOTO ,  Kazuhei KANEKO ,  Hirofumi OMURA ,  Motomasa TAKAHASHI ,  Makoto TAKAHASHI

IPC: C07K1/06 ,  C07C43/23 ,  C07C211/30 ,  C07C43/225 ,  C07C227/16

Abstract: Provided are a method for producing a peptide compound including a step of using a condensed polycyclic aromatic hydrocarbon compound represented by Formula (1); a protective group-forming reagent including the compound; and the compound. In Formula (1), a ring A represents a condensed polycyclic aromatic hydrocarbon ring, YA's each independently represent —OH, —NHR, —SH, or —X0, where X0 represents Cl, Br, or I, RA and RC each independently represent an aliphatic hydrocarbon group or an organic group having an aliphatic hydrocarbon group, RBs' each independently represent a monovalent aliphatic hydrocarbon group, a (1+c)-valent aromatic group, or a (1+c)-valent heteroaromatic group, where, in a case where both a and c is 0, RB is a monovalent aliphatic hydrocarbon group, and the number of carbon atoms in at least one aliphatic hydrocarbon group is 12 or more.

公开(公告)号：US20210380633A1

公开(公告)日：2021-12-09

申请号：US17409692

申请日：2021-08-23

Applicant: FUJIFILM CORPORATION

Inventor： Yosuke YAMAMOTO ,  Kazuhei KANEKO ,  Motomasa TAKAHASHI ,  Makoto TAKAHASHI ,  Mika IMAMURA ,  Hirotaka SATOU ,  Hirofumi OMURA ,  Yuji YOSHIMITSU ,  Keita TANAKA ,  Daisuke NAKAGAWA

IPC: C07K1/06 ,  C07K1/02

Abstract: Provided are a method for producing a peptide compound including a step of using an aromatic heterocyclic compound represented by Formula (1) represented by Formula (1); a protective group-forming reagent including the compound; and the compound. In Formula (1), a ring A represents an aromatic heterocyclic ring, YA's each independently represent —OH, —NHR, —SH, or —X0, where X0 represents Cl, Br, or I, RA and RC each independently represent an aliphatic hydrocarbon group or an organic group having an aliphatic hydrocarbon group, RBs' each independently represent a monovalent aliphatic hydrocarbon group, a (1+c)-valent aromatic group, or a (1+c)-valent heteroaromatic group, where, in a case where both a and c is 0, RB is a monovalent aliphatic hydrocarbon group, and the number of carbon atoms in at least one aliphatic hydrocarbon group of RA, RB, or RC is 12 or more.

公开(公告)号：US20200239495A1

公开(公告)日：2020-07-30

申请号：US16839563

申请日：2020-04-03

Applicant: FUJIFILM Corporation

Inventor： Muneo SHOJI ,  Kentaro FURUYA ,  Kei MATSUURA ,  Hiromi HAYASHI ,  Tetsuya MATSUSHITA ,  Hirofumi OMURA

IPC: C07D499/897

Abstract: An object of the present invention is to provide a compound and a pharmaceutical composition which exhibit strong antibacterial activity against Gram-negative bacteria and drug-resistant Gram-negative bacteria. According to the present invention, a compound represented by General Formula [1] (the reference signs in the formula have the same definitions as those described in the present specification) or a salt thereof has strong antibacterial activity against Gram-negative bacteria such as Pseudomonas aeruginosa and drug-resistant Gram-negative bacteria including multidrug-resistant Pseudomonas aeruginosa, and the pharmaceutical composition containing the compound or a salt thereof is useful as an antibacterial agent.

公开(公告)号：US20210380634A1

公开(公告)日：2021-12-09

申请号：US17408474

申请日：2021-08-22

Applicant: FUJIFILM CORPORATION

Inventor： Yosuke YAMAMOTO ,  Kazuhei KANEKO ,  Motomasa TAKAHASHI ,  Makoto TAKAHASHI ,  Mika IMAMURA ,  Hirotaka SATOU ,  Hirofumi OMURA ,  Yuji YOSHIMITSU ,  Daisuke NAKAGAWA ,  Keita TANAKA

IPC: C07K1/06 ,  C07C43/23

Abstract: Provided are a method for producing a peptide compound including a step of using a condensed polycyclic aromatic hydrocarbon compound represented by Formula (1); a protective group-forming reagent including the compound; and the compound. In Formula (1), a ring A represents a condensed polycyclic aromatic hydrocarbon ring, YA's each independently represent —CH2OH, —CH2NHR, —CH2SH, or —CH2X0, where R represents a hydrogen atom, an alkyl group, or an aralkyl group, and X0 represents Cl, Br, or I, k represents an integer of 1 to 5, n represents 1 or 2, and RA's each independently represent an aliphatic hydrocarbon group or an organic group having an aliphatic hydrocarbon group.

公开(公告)号：US20210063825A1

公开(公告)日：2021-03-04

申请号：US17092316

申请日：2020-11-08

Applicant: FUJIFILM Corporation

Inventor： Yutaka NOZOE ,  Takashi IIZUMI ,  Kazushige NAKAGAWA ,  Takahiro KATO ,  Miho ASAHI ,  Hirofumi OMURA ,  Yuki HIRAI

IPC: G02F1/1337 ,  G02F1/01 ,  C08F220/60 ,  C08F220/36 ,  C08F220/32

Abstract: An object of the invention is to provide a photo-alignment copolymer which makes it possible to produce a photo-alignment film having excellent solvent resistance and liquid crystal aligning properties, and a photo-alignment film and an optical laminate produced using the photo-alignment copolymer. A photo-alignment copolymer of the invention is a photo-alignment copolymer having a repeating unit A including a photo-alignment group represented by Formula (A) and a repeating unit B including a crosslinkable group represented by Formula (B).