公开(公告)号：US10828335B2

公开(公告)日：2020-11-10

申请号：US15614755

申请日：2017-06-06

Applicant: FUJIFILM Cellular Dynamics, Inc.

Inventor： Matt George ,  Carrie Chavez ,  Chris McMahon ,  Wen Bo Wang ,  Lucas Chase ,  Brad Swanson

IPC: A61K35/30 ,  B65D25/20 ,  G01N33/50 ,  C12N9/02 ,  C12Q1/68 ,  A61J1/00 ,  C12N5/0793 ,  C12Q1/6876

Abstract: Methods are provided for efficient production of midbrain dopaminergic (DA) neurons. In some aspects, methods involve differentiation and selection of DA neurons for a transgenic pluripotent cell population (e.g., cells comprising a selectable marker gene). Cell populations produced by the instant methods and methods of their use are likewise provided.