公开(公告)号：US08835182B2

公开(公告)日：2014-09-16

申请号：US13749148

申请日：2013-01-24

Applicant: FUJIFILM Corporation

Inventor： Junichi Katada ,  Hideyuki Karaki ,  Takayoshi Oyamada

IPC: G01N33/558 ,  G01N33/543

CPC classification number: G01N33/543 ,  G01N33/558 ,  Y10S435/805 ,  Y10S435/81 ,  Y10S435/97 ,  Y10S436/805 ,  Y10S436/81

Abstract: The present invention provides an immunochromatographic device, which contains the following (a) and (b): (a) a first device part holding a first insoluble carrier used for developing a complex formed with an analyte and a labeling substance comprising a metal labeled with a first binding substance that can bind to the analyte and capturing the analyte and the labeling substance at a reaction portion containing a second binding substance that can bind to the analyte, and (b) a second device part holding a second insoluble carrier used for developing a liquid and a third insoluble carrier used for absorbing a liquid, in such a way that the first insoluble carrier does not come into contact with the second insoluble carrier and the third insoluble carrier.

Abstract translation: 本发明提供一种免疫色谱装置，其包含以下（a）和（b）：（a）第一装置部分，其保持用于显影由分析物形成的复合物的第一不溶性载体和包含标记有 可以结合分析物并捕获分析物和标记物质的第一结合物质，所述反应部分含有能够结合分析物的第二结合物质，和（b）保持用于显影的第二不溶性载体的第二装置部分 用于吸收液体的液体和第三不溶性载体，使得第一不溶性载体不与第二不溶性载体和第三不溶性载体接触。

公开(公告)号：US09649281B2

公开(公告)日：2017-05-16

申请号：US14709555

申请日：2015-05-12

Applicant: FUJIFILM Corporation

Inventor： Junya Yoshida ,  Seiji Kasahara ,  Takayoshi Oyamada ,  Yanlong Che

IPC: A61K9/70 ,  A61M37/00 ,  A61K8/73 ,  A61Q19/08 ,  A61K8/02 ,  A61K9/00

CPC classification number: A61K9/703 ,  A61K8/0204 ,  A61K8/732 ,  A61K8/735 ,  A61K9/0021 ,  A61K38/27 ,  A61K38/385 ,  A61K2800/91 ,  A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0046 ,  A61M2037/0053 ,  A61Q19/08 ,  B29C41/22 ,  B29C59/005 ,  B29C59/022 ,  B29C2059/023 ,  B29K2995/0056 ,  B29K2995/0065 ,  B29L2031/7544

Abstract: A transdermal absorption sheet and a manufacturing method for the transdermal absorption sheet includes a laminating step of forming a multilayer film with a viscosity difference by forming, on a support, a lower layer containing a first transdermal absorption material and an upper layer containing a drug and a second transdermal absorption material and having a lower viscosity than the lower layer, a filling step of filling needle-like recessed portions corresponding to inverted needle-like protruding portions with a solution of the transdermal absorption material by pressing a mold in which the needle-like recessed portions are arranged in a two-dimensional array, against a surface of the multilayer film supported by the support to allow the multilayer film to flow, a solidifying step of solidifying the multilayer film with the mold pressed against the surface of the multilayer film, and a peeling-off step of peeling the solidified multilayer film from the mold.

公开(公告)号：US10029081B2

公开(公告)日：2018-07-24

申请号：US14709640

申请日：2015-05-12

Applicant: FUJIFILM Corporation

Inventor： Yanlong Che ,  Takayoshi Oyamada ,  Junya Yoshida ,  Shotaro Ogawa

IPC: B32B3/30 ,  A61M37/00 ,  A61K9/00 ,  B32B37/10 ,  B32B37/00 ,  B32B25/20 ,  B32B27/26 ,  B32B27/28 ,  B29C33/38 ,  B29C33/40 ,  B29C33/42 ,  B29L31/00

Abstract: A molding compact for forming a transdermal absorption sheet on which a needle-shaped protruding part is arranged is a molding compact that is a laminate of: a first member having a needle-shaped recessed part formed on a front surface thereof, the needle-shaped recessed part being an inverse of the needle-shaped protruding part; a second member provided on a back surface of the first member, the second member being composed of a waterproof and moisture-permeable material; and a third member provided on a back surface of the second member, the third member being composed of a rigid body. Provided are a molding compact that makes it possible to prevent leakage of a drug-containing solution filled into the needle-shaped recessed part, and a manufacturing method for a transdermal absorption sheet using the molding compact.

公开(公告)号：US10166182B2

公开(公告)日：2019-01-01

申请号：US15281325

申请日：2016-09-30

Applicant: FUJIFILM Corporation ,  NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY

Inventor： Koji Kuruma ,  Takayoshi Oyamada ,  Toshio Shimada ,  Yoshihiro Sakoda ,  Hiroshi Kida

IPC: A61K39/12 ,  A61K39/145 ,  A61K9/00 ,  A61K39/00

Abstract: Provided is a microneedle. The microneedle array includes a needle portion, which contains an inactivated whole virion influenza vaccine, and a sheet portion. Also provided is an administration method in which the microneedle array is administered and then administered secondly after an interval of equal to or greater than 24 hours and less than 2 months.

公开(公告)号：US09987236B2

公开(公告)日：2018-06-05

申请号：US15403588

申请日：2017-01-11

Applicant: FUJIFILM Corporation

Inventor： Junya Yoshida ,  Seiji Kasahara ,  Takayoshi Oyamada ,  Yanlong Che

IPC: A61K9/70 ,  A61M37/00 ,  A61K8/73 ,  A61Q19/08 ,  A61K8/02 ,  A61K9/00 ,  A61K38/27 ,  A61K38/38 ,  B29C41/22 ,  B29C59/00 ,  B29C59/02 ,  B29L31/00

CPC classification number: A61K9/703 ,  A61K8/0204 ,  A61K8/732 ,  A61K8/735 ,  A61K9/0021 ,  A61K38/27 ,  A61K38/385 ,  A61K2800/91 ,  A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0046 ,  A61M2037/0053 ,  A61Q19/08 ,  B29C41/22 ,  B29C59/005 ,  B29C59/022 ,  B29C2059/023 ,  B29K2995/0056 ,  B29K2995/0065 ,  B29L2031/7544

Abstract: A transdermal absorption sheet and a manufacturing method for the transdermal absorption sheet includes a laminating step of forming a multilayer film with a viscosity difference by forming, on a support, a lower layer containing a first transdermal absorption material and an upper layer containing a drug and a second transdermal absorption material and having a lower viscosity than the lower layer, a filling step of filling needle-like recessed portions corresponding to inverted needle-like protruding portions with a solution of the transdermal absorption material by pressing a mold in which the needle-like recessed portions are arranged in a two-dimensional array, against a surface of the multilayer film supported by the support to allow the multilayer film to flow, a solidifying step of solidifying the multilayer film with the mold pressed against the surface of the multilayer film, and a peeling-off step of peeling the solidified multilayer film from the mold.