公开(公告)号：US20240229015A1

公开(公告)日：2024-07-11

申请号：US18611981

申请日：2024-03-21

Applicant: FUJIFILM Corporation

Inventor： Yukiko ISHII ,  Jo TOMINAGA ,  Shiori KIHARA ,  Takahiro HOHSAKA ,  Takayoshi WATANABE

IPC: C12N15/10 ,  C12N15/113

CPC classification number: C12N15/1062 ,  C12N15/1044 ,  C12N15/1096 ,  C12N15/113

Abstract: Provided are a tRNA obtained by modifying a tRNA for tryptophan of Mycoplasma pneumoniae, the tRNA including a UUA as an anticodon to pair with a UAA codon, and an application of the tRNA.

公开(公告)号：US20210213040A1

公开(公告)日：2021-07-15

申请号：US17213567

申请日：2021-03-26

Applicant: FUJIFILM Corporation

Inventor： Satoshi KITAZAWA ,  Yukiko ISHII ,  Koichi SAITO ,  Shun MATSUDA

IPC: A61K31/7068 ,  A61K45/06 ,  A61K31/455

Abstract: An object of the present invention is to provide a combination drug containing cytarabine and a DHODH inhibitor, as a new anti-tumor agent, and to provide an anti-tumor effect enhancing agent which is used in combination with cytarabine, an anti-tumor kit, and an anti-tumor agent which is used in combination with cytarabine. According to the present invention, an anti-tumor agent and an anti-tumor kit containing cytarabine and a dihydroorotate dehydrogenase inhibitor compound are provided.