公开(公告)号：US06867011B1

公开(公告)日：2005-03-15

申请号：US09308671

申请日：1997-12-04

申请人： Fabienne Noelle Babin ,  Charles Didier Calzolari ,  Odile Suzanne Helene Flecheux ,  Claude Granier ,  Catherine Christiane Marie Larue ,  Bernard Christian Pau ,  Francois Yves Rieunier ,  Sylvie Marie-France Trinquier

发明人： Fabienne Noelle Babin ,  Charles Didier Calzolari ,  Odile Suzanne Helene Flecheux ,  Claude Granier ,  Catherine Christiane Marie Larue ,  Bernard Christian Pau ,  Francois Yves Rieunier ,  Sylvie Marie-France Trinquier

IPC分类号： G01N33/53 ,  C07K14/47 ,  G01N33/535 ,  C07K1/13

CPC分类号： C07K14/4716 ,  G01N2333/4712 ,  Y10S435/967 ,  Y10T436/10 ,  Y10T436/105831

摘要： The invention relates to synthetic biepitope compounds which can be used as standards in immunoassays, for the assay of troponin I, method for preparing them, compositions and kits containing such compounds as well as the immunoassay methods using such compounds.

摘要翻译： 本发明涉及可用作免疫测定中的标准物，肌钙蛋白I的测定法，其制备方法，含有这些化合物的组合物和试剂盒以及使用这些化合物的免疫测定方法的合成生物表皮化合物。

公开(公告)号：US08013115B1

公开(公告)日：2011-09-06

申请号：US10048978

申请日：2000-08-14

申请人： Isabelle Nathalie Garric ,  Isabelle Karine Giuliani ,  Catherine Christiane Marie Larue ,  François Yves Rieunier ,  Sylvie Marie-France Trinquier

发明人： Isabelle Nathalie Garric ,  Isabelle Karine Giuliani ,  Catherine Christiane Marie Larue ,  François Yves Rieunier ,  Sylvie Marie-France Trinquier

IPC分类号： C07K7/50 ,  G01N33/68

CPC分类号： G01N33/531 ,  G01N33/6887 ,  G01N2333/4712

摘要： The invention concerns the use of at least a synthetic compound comprising: a carrier molecule having at least a hydrocarbon chain comprising at least 10, advantageously at least 12, preferably at least 14 and not more than 300, advantageously not more than 100, preferably not more than 50, selected'among C, N, O, S, P and Si, and comprising at least two reactive functions, or capable of reacting, for grafting lateral arms on said chain, and at least two different epitopes carried by said lateral arms grafted on said carrier molecule, as standard or control for immunoassay of said biological molecules, in particular of polypeptides or proteins.

摘要翻译： 本发明涉及使用至少一种合成化合物，其包括：载体分子，其具有至少包含至少10个，有利地至少12个，优选至少14个，且不多于300个，有利地不多于100个，优选不大于100个的烃链 超过50个，选择的C，N，O，S，P和Si，并且包含至少两个反应性函数，或能够反应，用于接枝所述链上的侧臂，以及至少两个不同的表位， 作为标准的移植在所述载体分子上的臂，所述生物分子尤其是多肽或蛋白质的免疫测定的对照。