公开(公告)号：US06591124B2

公开(公告)日：2003-07-08

申请号：US09853442

申请日：2001-05-11

申请人： Faiz Feisal Sherman ,  Francisco Arias ,  Vladimir Gartstein ,  Grover David Owens ,  Milan Marcel Jevtitch ,  Chow Chi Huang

发明人： Faiz Feisal Sherman ,  Francisco Arias ,  Vladimir Gartstein ,  Grover David Owens ,  Milan Marcel Jevtitch ,  Chow Chi Huang

IPC分类号： A61B505

CPC分类号： A61B5/1486 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/150022 ,  A61B5/150076 ,  A61B5/150099 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150358 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150938 ,  A61B5/150969 ,  A61B5/150984 ,  A61B5/15105 ,  A61B5/15113 ,  A61B5/15125 ,  A61B5/15142 ,  A61B5/15153 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15178 ,  A61B5/15186 ,  A61B5/155 ,  A61B5/157 ,  A61B2560/04 ,  A61B2562/0295 ,  A61M37/0015 ,  A61M2230/201

摘要： A strip-like microneedle device is provided that includes an array of hollow microneedles, a diaphragm pump to extract interstitial fluid from skin, and a sensor that detects the concentration of the fluid. The microneedle device can be interfaced to an external sensor to produce a reading, or can be self-contained. One version uses an attachable/detachable microneedle array as a single-use, disposable unit. The device is portable, and is used by placing one finger on the microneedle array, and actuating the diaphragm pump with another finger, thereby obtaining the fluid sample. Solid coated or transparent microneedles could instead be used as an in-situ sensor, with either electrodes or an optical sensor.