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801 条记录 (耗时 0.023 秒)

    Device for sampling one or more analytes
    1.
    发明授权
    Device for sampling one or more analytes 有权

    公开(公告)号：US12102304B2

    公开(公告)日：2024-10-01

    申请号：US17440662

    申请日：2020-02-04

    申请人： GLUCOMODICUM OY

    发明人： Alejandro Garcia Perez

    IPC分类号： A61B10/00 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1477

    CPC分类号： A61B10/0045 ,  A61B5/002 ,  A61B5/14514 ,  A61B5/14546 ,  A61B5/1477 ,  A61B5/6832 ,  A61B5/746 ,  A61B2010/008 ,  A61B2560/0425

    摘要： Disclosed is a device for non-invasively sampling interstitial fluid including one or more analytes from dermis to the skin surface by employing the magneto-hydrodynamic effect and/or reverse iontophoresis. According to a preferable embodiment the device includes a first frame including a first electrode and a second frame including a second electrode, power source and preferably also a first magnet. The first frame is connected to the second frame by a formable connector adapted to provide mechanical connection between the first frame and the second frame and electrical connection between the power source and the first electrode. The direction of the magnetic field and the direction of the electric current produced by the magnet and the power source is such that the Lorenz force drives the fluid from the dermis towards the skin surface.

    Aptamer based portable diagnostic medical device and methods of use
    5.
    发明授权
    Aptamer based portable diagnostic medical device and methods of use 有权

    公开(公告)号：US11896369B2

    公开(公告)日：2024-02-13

    申请号：US16699534

    申请日：2019-11-29

    申请人： Ismael Marvin Voltaire

    发明人： Ismael Marvin Voltaire

    IPC分类号： A61B5/145 ,  A61B5/00 ,  A61B5/1455

    CPC分类号： A61B5/14514 ,  A61B5/0024 ,  A61B5/14503 ,  A61B5/14546 ,  A61B5/14556 ,  A61B5/6824 ,  A61B5/6828

    摘要： The present invention is directed to a cuff-like medical device that may analyze and report the concentrations of various biomarkers in a subject's bodily fluids, samples of which may be extracted by the device in the field and analyzed on the spot using the cuff-like medical device. For example, extracellular fluid (commonly known as “tissue fluid”) of a patient may be analyzed by the present invention, and in particular, the constituent interstitial fluid—the known main component of extracellular fluid—may be analyzed for concentrations of one or more specific types of proteins. A sensor component within the device may include one or more aptamers that permit chemical binding of at least one biomarker of interest. When the aptamer-protein binding complex is complete, an electronic component of the device may employ nanoscale weighing using frequency differential analysis through quartz crystal microbalances to determine the presence and concentration of biomarkers.

    Fault detection for microneedle array based continuous analyte monitoring device
    6.
    发明授权
    Fault detection for microneedle array based continuous analyte monitoring device 有权

    公开(公告)号：US11857344B2

    公开(公告)日：2024-01-02

    申请号：US17738990

    申请日：2022-05-06

    申请人： Biolinq Incorporated

    发明人： Joshua Ray Windmiller ,  Alan Steven Campbell ,  Jared Rylan Tangney

    IPC分类号： A61B5/145 ,  A61B5/00

    CPC分类号： A61B5/685 ,  A61B5/14514 ,  A61B5/14532

    摘要： Fault detection and diagnostics for a microneedle array based continuous analyte monitoring device are provided. The electrochemical sensors, including the electrodes of the analyte monitoring device configured for measuring one or more target analytes, may experience various faults during use of the analyte monitoring device. By modeling the sensors as an electrical network, measurements of the electrical network may be correlated with operational parameters of the sensor. The voltage at the counter electrode provides an indication of the resistance or impedance between the working electrode and the counter electrode and is used to identify the occurrence of faults occurring at the continuous analyte monitoring device.