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公开(公告)号：US08644652B2
公开(公告)日：2014-02-04
申请号：US13510925
申请日：2011-06-29
申请人： Fei Xu , Junlong Kou , Yanqing Lu , Wei Hu
发明人： Fei Xu , Junlong Kou , Yanqing Lu , Wei Hu
CPC分类号： G02B6/10 , G01N21/255 , G01N21/7703 , G01N21/7746 , G02B6/032
摘要： The present application relates to optical fibers having at least one slot. The optical fiber may be used, for example, in various sensing application. In some embodiments, a cross-section of the optical fiber perpendicular to the longitudinal axis has a largest dimension less than or equal to about 4 μm, and the slot has a width of about 5 nm to about 500 nm and a depth of at least about 10 nm. Also disclosed herein are methods of using the optical fibers and apparatuses including the optical fibers.
摘要翻译： 本申请涉及具有至少一个槽的光纤。 光纤可以用于例如各种传感应用中。 在一些实施例中，垂直于纵向轴线的光纤的横截面具有小于或等于约4μm的最大尺寸，并且狭槽具有约5nm至约500nm的宽度和至少的深度 约10nm。 本文还公开了使用包括光纤的光纤和设备的方法。
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公开(公告)号：US20130114923A1
公开(公告)日：2013-05-09
申请号：US13510925
申请日：2011-06-29
申请人： Fei Xu , Junlong Kou , Yanqing Lu , Wei Hu
发明人： Fei Xu , Junlong Kou , Yanqing Lu , Wei Hu
CPC分类号： G02B6/10 , G01N21/255 , G01N21/7703 , G01N21/7746 , G02B6/032
摘要： The present application relates to optical fibers having at least one slot. The optical fiber may be used, for example, in various sensing application. In some embodiments, a cross-section of the optical fiber perpendicular to the longitudinal axis has a largest dimension less than or equal to about 4 μm, and the slot has a width of about 5 nm to about 500 nm and a depth of at least about 10 nm. Also disclosed herein are methods of using the optical fibers and apparatuses including the optical fibers.
摘要翻译： 本申请涉及具有至少一个槽的光纤。 光纤可以用于例如各种传感应用中。 在一些实施例中，垂直于纵向轴线的光纤的横截面具有小于或等于约4μm的最大尺寸，并且狭槽具有约5nm至约500nm的宽度和至少的深度 约10nm。 本文还公开了使用包括光纤的光纤和设备的方法。
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公开(公告)号：US09116300B2
公开(公告)日：2015-08-25
申请号：US13146308
申请日：2010-06-25
申请人： Yanqing Lu , Shuyi Zhang , Qi Zhong , Fei Xu , Xiaowen Lin , Wei Hu
发明人： Yanqing Lu , Shuyi Zhang , Qi Zhong , Fei Xu , Xiaowen Lin , Wei Hu
CPC分类号： G02B6/29344 , G01J2009/004 , G01N21/45 , G02B6/02295 , G02B6/14 , G02B6/2551 , G02B6/262
摘要： Technologies are generally described for techniques useful in an interferometer system. In some examples, a system may include a first waveguide effective to propagate a first wave in a first mode. In some examples, the system may include a second waveguide effective to, in response to the first wave, propagate second and third waves in second and third modes, respectively. In some examples, the second waveguide may be effective to reflect the second and third waves off a reflection surface to produce first, second, third and fourth reflected waves. In some examples, the second waveguide may be effective to propagate the first and third reflected waves in the second mode and propagate the second and fourth reflected waves in the third mode.
摘要翻译： 技术通常描述用于干涉仪系统中的技术。 在一些示例中，系统可以包括有效地在第一模式中传播第一波的第一波导。 在一些示例中，系统可以包括有效响应于第一波的第二波导，其分别在第二和第三模式中传播第二和第三波。 在一些示例中，第二波导可以有效地将第二和第三波从反射表面反射以产生第一，第二，第三和第四反射波。 在一些示例中，第二波导可以有效地在第二模式中传播第一和第三反射波，并且在第三模式中传播第二和第四反射波。
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公开(公告)号：US09796002B2
公开(公告)日：2017-10-24
申请号：US13817357
申请日：2012-03-05
申请人： Yanqing Lu , Xikui Hu , Fei Xu , Wei Hu
发明人： Yanqing Lu , Xikui Hu , Fei Xu , Wei Hu
CPC分类号： B08B7/026
摘要： Technologies are generally described for systems and methods effective to implement particle removal. In one example, a method for at least partially removing particles from a region is generally described. In some examples, the method includes applying an electric field to a material to produce an acoustic wave from the material. The material may have a periodic piezoelectric coefficient. The method may include applying the acoustic wave to the region to produce an agglomeration. The agglomeration may include at least two of the particles. The method may further include at least partially removing the agglomeration from the region.
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公开(公告)号：US20130239989A1
公开(公告)日：2013-09-19
申请号：US13817357
申请日：2012-03-05
申请人： Yanqing Lu , Xikui Hu , Fei Xu , Wei Hu
发明人： Yanqing Lu , Xikui Hu , Fei Xu , Wei Hu
IPC分类号： B08B7/02
CPC分类号： B08B7/026
摘要： Technologies are generally described for systems and methods effective to implement particle removal. In one example, a method for at least partially removing particles from a region is generally described. In some examples, the method includes applying an electric field to a material to produce an acoustic wave from the material. The material may have a periodic piezoelectric coefficient. The method may include applying the acoustic wave to the region to produce an agglomeration. The agglomeration may include at least two of the particles. The method may further include at least partially removing the agglomeration from the region.
摘要翻译： 通常描述了有效实现颗粒去除的系统和方法的技术。 在一个实例中，通常描述从区域至少部分去除颗粒的方法。 在一些示例中，该方法包括向材料施加电场以从该材料产生声波。 该材料可以具有周期性的压电系数。 该方法可以包括将声波施加到该区域以产生聚集。 团聚可以包括至少两个颗粒。 所述方法还可以包括至少部分地从该区域除去附聚物。
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公开(公告)号：US20120224806A1
公开(公告)日：2012-09-06
申请号：US13146308
申请日：2010-06-25
申请人： Yanqing Lu , Shuyi Zhang , Qi Zhong , Fei Xu , Xiaowen Lin , Wei Hu
发明人： Yanqing Lu , Shuyi Zhang , Qi Zhong , Fei Xu , Xiaowen Lin , Wei Hu
IPC分类号： G02B6/14
CPC分类号： G02B6/29344 , G01J2009/004 , G01N21/45 , G02B6/02295 , G02B6/14 , G02B6/2551 , G02B6/262
摘要： Technologies are generally described for techniques useful in an interferometer system. In some examples, a system may include a first waveguide effective to propagate a first wave in a first mode. In some examples, the system may include a second waveguide effective to, in response to the first wave, propagate second and third waves in second and third modes, respectively. In some examples, the second waveguide may be effective to reflect the second and third waves off a reflection surface to produce first, second, third and fourth reflected waves. In some examples, the second waveguide may be effective to propagate the first and third reflected waves in the second mode and propagate the second and fourth reflected waves in the third mode.
摘要翻译： 技术通常描述用于干涉仪系统中的技术。 在一些示例中，系统可以包括有效地在第一模式中传播第一波的第一波导。 在一些示例中，系统可以包括有效响应于第一波的第二波导，其分别在第二和第三模式中传播第二和第三波。 在一些示例中，第二波导可以有效地将第二和第三波从反射表面反射以产生第一，第二，第三和第四反射波。 在一些示例中，第二波导可以有效地在第二模式中传播第一和第三反射波，并且在第三模式中传播第二和第四反射波。
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公开(公告)号：US08137736B2
公开(公告)日：2012-03-20
申请号：US12348589
申请日：2009-01-05
申请人： Mingwei Zhu , Yanfeng Chen , Zhenlin Wang , Yanqing Lu , Haixiong Ge , Yuefeng Tang
发明人： Mingwei Zhu , Yanfeng Chen , Zhenlin Wang , Yanqing Lu , Haixiong Ge , Yuefeng Tang
IPC分类号： B05D3/12
CPC分类号： B81C1/00476 , A61M37/0015 , A61M2037/003 , A61M2037/0053 , B81B2201/055 , B81B2203/0338 , B81B2203/0361 , B81C2201/0108
摘要： A novel method suitable for commercially mass production of hollow microneedle with high quality for delivery of drugs across or into biological tissue is provided. It typically includes the following processes: (1) coating an elongated template of a first material with a second material to form a cover; (2) removing tips of the template and cover to form an opening in the cover; and (3) removing the template of the first material to obtain hollow microneedles of the second material. This simple, efficient and cost-effective fabrication method can mass produce hollow microneedle arrays involving no complicated and expensive equipments or techniques, which can be used in commercial fabrication of hollow needles for delivering drugs or genes across or into skin or other tissue barriers with advantages of minimal damage, painless, long-term and continuous usages.
摘要翻译： 提供了一种适用于商业上大规模生产用于将药物跨越或进入生物组织的高品质的中空微针的新方法。 它通常包括以下过程：（1）用第二材料涂覆第一材料的细长模板以形成盖子; （2）去除模板和盖子的尖端以在盖子上形成开口; 和（3）去除第一材料的模板以获得第二材料的中空微针。 这种简单，高效和成本有效的制造方法可以大规模生产中空微针阵列，其不涉及复杂而昂贵的设备或技术，其可用于商业制造用于将药物或基因跨越或进入皮肤或其它组织屏障的中空针 最小的伤害，无痛，长期和持续的使用。
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公开(公告)号：US20100062142A1
公开(公告)日：2010-03-11
申请号：US12348589
申请日：2009-01-05
申请人： Mingwei Zhu , Yanfeng Chen , Zhenlin Wang , Yanqing Lu , Haixiong Ge , Yuefeng Tang
发明人： Mingwei Zhu , Yanfeng Chen , Zhenlin Wang , Yanqing Lu , Haixiong Ge , Yuefeng Tang
IPC分类号： B05D3/00
CPC分类号： B81C1/00476 , A61M37/0015 , A61M2037/003 , A61M2037/0053 , B81B2201/055 , B81B2203/0338 , B81B2203/0361 , B81C2201/0108
摘要： A novel method suitable for commercially mass production of hollow microneedle with high quality for delivery of drugs across or into biological tissue is provided. It typically includes the following processes: (1) coating an elongated template of a first material with a second material to form a cover; (2) removing tips of the template and cover to form an opening in the cover; and (3) removing the template of the first material to obtain hollow microneedles of the second material. This simple, efficient and cost-effective fabrication method can mass produce hollow microneedle arrays involving no complicated and expensive equipments or techniques, which can be used in commercial fabrication of hollow needles for delivering drugs or genes across or into skin or other tissue barriers with advantages of minimal damage, painless, long-term and continuous usages.
摘要翻译： 提供了一种适用于商业上大规模生产用于将药物跨越或进入生物组织的高品质的中空微针的新方法。 它通常包括以下过程：（1）用第二材料涂覆第一材料的细长模板以形成盖子; （2）去除模板和盖子的尖端以在盖子上形成开口; 和（3）去除第一材料的模板以获得第二材料的中空微针。 这种简单，高效和成本有效的制造方法可以大规模生产中空微针阵列，其不涉及复杂而昂贵的设备或技术，其可用于商业制造用于将药物或基因跨越或进入皮肤或其它组织屏障的中空针 最小的伤害，无痛，长期和持续的使用。
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